Featured Research

from universities, journals, and other organizations

New Studies Highlight The Importance Of Bowel Prep And Effectiveness Of Colonoscopy

Date:
October 6, 2008
Source:
American College of Gastroenterology
Summary:
New research emphasizes the importance of adequate bowel preparation prior to colonoscopy, and highlights the remarkable effectiveness of colonoscopy in detecting and removing pre-cancerous polyps, particularly tiny, flat, potentially pre-cancerous growths in the colon known as "sessile serrated adenomas."

New research presented at the American College of Gastroenterology's 73rd Annual Scientific Meeting in Orlando emphasizes the importance of adequate bowel preparation prior to colonoscopy, and highlights the remarkable effectiveness of colonoscopy in detecting and removing pre-cancerous polyps, particularly tiny, flat, potentially pre-cancerous growths in the colon known as "sessile serrated adenomas."

Dr. Brindusa Truta and Francisco C. Ramirez of the Carl T. Hayden VA Medical Center in Phoenix analyzed data of 21,600 colonoscopies performed at their institution from January 1998 to December 2007.

Researchers analyzed findings from 280 patients who underwent more than one colonoscopy in the last ten years, and had at least one positive fecal occult blood test (FOBT). Twenty two percent (57 patients) of these patients had a 'cleared' exam, but underwent repeat colonoscopy after receiving a positive FOBT result. Researchers found 5 percent of patients had colon cancer, 33 percent had adenomatous polyps, and 26 percent of patients with adenomas had advanced neoplasia. The average time interval between the first colonoscopy and the repeat colonoscopy for a positive FOBT was 39 months. Poor quality bowel preparation at the initial colonoscopy was associated with more missed cancers and undetected polyps.

According to lead investigator Dr. Truta, "A positive fecal occult blood test after a 'cleared' colonoscopy should trigger a repeat colonoscopy, especially if a suboptimal bowel preparation was encountered at the initial exam."

Not All Small Polyps Are Innocent

In a separate study, Dr. Suryakanth R. Gurudu and his colleagues at Mayo Clinic in Scottsdale, Arizona examined medical records from the Clinic's pathology database of patients who had sessile serrated adenomas removed with colonoscopy between 2005 and 2007.

Sessile serrated adenomas are a sub-class of tiny, flat pre-cancerous polyps, often found on the right side of the colon. "While small polyps are generally considered less dangerous than large polyps, not all small polyps are innocent," said lead investigator Dr. Gurudu.

Of the 5,991 patients who were found to have polyps, sessile serrated adenomas comprised 2.9 percent of all polyps removed. The sessile serrated adenomas were small and 42 percent were less than or equal to 5mm in size, while 69 percent were less than or equal to 9 mm in size. Ninety-seven percent of polyps were removed by colonoscopy and 2.7 percent required surgical excision.

According to Dr. Gurudu, "Many of these polyps due to their size and shape might have gone undetected or not reported on an x-ray exam of the colon known as CT colonography. The effectiveness of cancer prevention comes from removing all precancerous lesions with colonoscopy, regardless of size."


Story Source:

The above story is based on materials provided by American College of Gastroenterology. Note: Materials may be edited for content and length.


Cite This Page:

American College of Gastroenterology. "New Studies Highlight The Importance Of Bowel Prep And Effectiveness Of Colonoscopy." ScienceDaily. ScienceDaily, 6 October 2008. <www.sciencedaily.com/releases/2008/10/081006102531.htm>.
American College of Gastroenterology. (2008, October 6). New Studies Highlight The Importance Of Bowel Prep And Effectiveness Of Colonoscopy. ScienceDaily. Retrieved September 19, 2014 from www.sciencedaily.com/releases/2008/10/081006102531.htm
American College of Gastroenterology. "New Studies Highlight The Importance Of Bowel Prep And Effectiveness Of Colonoscopy." ScienceDaily. www.sciencedaily.com/releases/2008/10/081006102531.htm (accessed September 19, 2014).

Share This



More Health & Medicine News

Friday, September 19, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Could Grief Affect The Immune Systems Of Senior Citizens?

Could Grief Affect The Immune Systems Of Senior Citizens?

Newsy (Sep. 19, 2014) The study found elderly people are much more likely to become susceptible to infection than younger adults going though a similar situation. Video provided by Newsy
Powered by NewsLook.com
Jury Delivers Verdict in Salmonella Trial

Jury Delivers Verdict in Salmonella Trial

AP (Sep. 19, 2014) A federal jury has convicted three people in connection with an outbreak of salmonella poisoning five years ago that sickened hundreds of people and was linked to a number of deaths. (Sept. 19) Video provided by AP
Powered by NewsLook.com
How The 'Angelina Jolie Effect' Increased Cancer Screenings

How The 'Angelina Jolie Effect' Increased Cancer Screenings

Newsy (Sep. 19, 2014) Angelina's Jolie's decision to undergo a preventative mastectomy in 2013 inspired many women to seek early screenings for the disease. Video provided by Newsy
Powered by NewsLook.com
The Cost of Ebola

The Cost of Ebola

Reuters - Business Video Online (Sep. 18, 2014) As Sierra Leone prepares for a three-day "lockdown" in its latest bid to stem the spread of Ebola, Ciara Lee looks at the financial implications of fighting the largest ever outbreak of the disease. Video provided by Reuters
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins