Featured Research

from universities, journals, and other organizations

Allergy Patch Test: Children Tend To React To Different Allergens Than Adults

Date:
October 22, 2008
Source:
JAMA and Archives Journals
Summary:
Adults and children who are referred for patch testing of allergens appear equally likely to have allergic contact dermatitis, although they tend to react to different allergens, according to a new report.

Adults and children who are referred for patch testing of allergens appear equally likely to have allergic contact dermatitis, although they tend to react to different allergens, according to a new report.

Skin reactions to allergens are common among children, according to background information in the article. They can occur both on areas of the skin that come in direct contact with an allergen (contact dermatitis) and on areas that aren't directly affected (atopic dermatitis). Children suspected of contact dermatitis are often referred for patch testing, in which skin is exposed to various allergens affixed to a plaster tape to identify which cause a reaction.

Kathryn A. Zug, M.D., of Dartmouth-Hitchcock Medical Center, Lebanon, N.H., and colleagues analyzed results from 391 children age 18 and younger who underwent patch testing between 2001 and 2004. They compared results of the pediatric population to a group of 9,670 adults (age 19 and older) who were tested during the same time period.

Children and adults tested positive for at least one allergen at approximately the same rate (51.2 percent for children vs. 54.1 percent for adults). "Our study showed significant differences between the frequency of individual positive reactions to allergen patch tests in children and adults; children were more likely to have reactions to nickel, cobalt, thimerosal and lanolin, whereas adults were more likely to have positive reactions to neomycin, fragrance mix, M. pereirae (balsam of Peru [an extract from the balsam tree used as an alternative therapy]) and quaternium 15," the authors write.

The common positive reactions in children are expected given probable exposure patterns among this population. Some children reacted to supplemental allergens not included in common patch test series (15 percent) or in commercially available tests (39 percent). Children with a positive reaction were more likely to have atopic dermatitis included as one of their final diagnoses than were adults (34 percent vs. 11.2 percent).

"Patch testing in children suspected of having allergic contact dermatitis is a valuable endeavor. Despite their limited back size, an expanded allergen series helps to identify important positive relevant allergens. Allergen concentration does not need modification for testing in children," the authors conclude. "The top 45 allergens with the most frequent positive and relevant reactions reported in this study should serve as a guide to patch testing in children suspected of having allergic contact dermatitis in North America. Including supplemental allergens to the patch test materials based on clinical suspicion is also useful in some patients."

This study was supported by an American Contact Dermatitis Society Clinical Research Award the Nethercott Award for the study of epidemiology of contact dermatitis.


Story Source:

The above story is based on materials provided by JAMA and Archives Journals. Note: Materials may be edited for content and length.


Journal Reference:

  1. Kathryn A. Zug; Daniel McGinley-Smith; Erin M. Warshaw; James S. Taylor; Robert L. Rietschel; Howard I. Maibach; Donald V. Belsito; Joseph F. Fowler, Jr; Frances J. Storrs; Vincent A. DeLeo; James G. Marks, Jr; C. G. Toby Mathias; Melanie D. Pratt; Denis Sasseville. Contact Allergy in Children Referred for Patch Testing: North American Contact Dermatitis Group Data, 2001-2004. Arch Dermatol., 2008;144(10):1329-1336 [link]

Cite This Page:

JAMA and Archives Journals. "Allergy Patch Test: Children Tend To React To Different Allergens Than Adults." ScienceDaily. ScienceDaily, 22 October 2008. <www.sciencedaily.com/releases/2008/10/081020171331.htm>.
JAMA and Archives Journals. (2008, October 22). Allergy Patch Test: Children Tend To React To Different Allergens Than Adults. ScienceDaily. Retrieved July 23, 2014 from www.sciencedaily.com/releases/2008/10/081020171331.htm
JAMA and Archives Journals. "Allergy Patch Test: Children Tend To React To Different Allergens Than Adults." ScienceDaily. www.sciencedaily.com/releases/2008/10/081020171331.htm (accessed July 23, 2014).

Share This




More Health & Medicine News

Wednesday, July 23, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Idaho Boy Helps Brother With Disabilities Complete Triathlon

Idaho Boy Helps Brother With Disabilities Complete Triathlon

Newsy (July 23, 2014) An 8-year-old boy helped his younger brother, who has a rare genetic condition that's confined him to a wheelchair, finish a triathlon. Video provided by Newsy
Powered by NewsLook.com
Thousands Who Can't Afford Medical Care Flock to Free US Clinic

Thousands Who Can't Afford Medical Care Flock to Free US Clinic

AFP (July 23, 2014) America may be the world’s richest country, but in terms of healthcare, the World Health Organisation ranks it 37th. Thousands turned out for a free clinic run by "Remote Area Medical" with a visit from the Governor of Virginia. Duration: 2:40 Video provided by AFP
Powered by NewsLook.com
Stone Fruit Listeria Scare Causes Sweeping Recall

Stone Fruit Listeria Scare Causes Sweeping Recall

Newsy (July 22, 2014) The Wawona Packing Company has issued a voluntary recall on the stone fruit it distributes due to a possible Listeria outbreak. Video provided by Newsy
Powered by NewsLook.com
Huge Schizophrenia Study Finds Dozens Of New Genetic Causes

Huge Schizophrenia Study Finds Dozens Of New Genetic Causes

Newsy (July 22, 2014) The 83 new genetic markers could open dozens of new avenues for schizophrenia treatment research. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins