Featured Research

from universities, journals, and other organizations

What Is The Etiology Of Cardiac Syndrome X?

Date:
December 1, 2008
Source:
World Journal of Gastroenterology
Summary:
Cardiac syndrome X, a special subform of non-cardiac chest pain with abnormal electrocardiographic but normal coronary angiogram, originates mostly from disorders of the esophagus and stomach. A research group in Germany investigate the frequency of gastroenterological diseases in the etiology and the efficacy of proton pump inhibitors in the treatment of CSX as a subform of non-cardiac chest pain.

Non-cardiac chest pain remains a widespread symptom especially in western countries with a significant economic burden. Patients with chest pain and abnormal electrocardiographic (ECG) but normal coronary angiogram (i.e. exclusion of coronary heart disease) is termed Cardiac syndrome X (CSX) and represents a specific subform of non-cardiac chest pain. While etiology of non-cardiac chest pain has been studied in several projects, it is unclear in what extent CSX is based on disorders of the upper gastrointestinal disorder (GI) tract.

A research group in Aachen, Germany, interviewed 119 patients with abnormal ECG findings after having received a normal coronary angiogram.

Their result will be published on November 14, 2008 in the World Journal of Gastroenterology. The research team led by Dr. Christoph. Dietrich from Medizinische Klinik II in Germany interviewed 119 patients with abnormal ECG findings after having received a normal coronary angiogram. Surprisingly, almost 30% of patients did not exhibit typical chest pain anymore as they had before the diagnostic procedure.

On the other hand, 97% of still symptomatic patients undergoing gastroenterological workup, had signs of acid-related disorders of the upper GI tract including reflux esophagitis and gastritis. Unlike in many patients with general non-cardiac chest pain, motility disorders of the esophagus do not seem to play a role in CSX. Treatment with proton pump inhibitors led to a significant improvement of symptoms with a considerable amount of symptom-free patients.

They concluded that in patients with CSX, acid-related disorders are frequent and respond very well to a long-term therapy with pantoprazole. This study emphasizes the need of further diagnostic work up for this special patient group which suffers from serious pain attacks mostly over a period of several years.


Story Source:

The above story is based on materials provided by World Journal of Gastroenterology. Note: Materials may be edited for content and length.


Journal Reference:

  1. Dietrich CG, Laupichler S, Stanzel S, Winograd R, Al-Taie O, Gartung C, Geier A. Origin of and therapeutic approach to cardiac syndrome X: Results of the proton pump inhibitor therapy for angina-like lingering pain trial (PITFALL trial). World J Gastroenterol, 2008; 14 (42): 6506-6512 [link]

Cite This Page:

World Journal of Gastroenterology. "What Is The Etiology Of Cardiac Syndrome X?." ScienceDaily. ScienceDaily, 1 December 2008. <www.sciencedaily.com/releases/2008/12/081201100830.htm>.
World Journal of Gastroenterology. (2008, December 1). What Is The Etiology Of Cardiac Syndrome X?. ScienceDaily. Retrieved September 23, 2014 from www.sciencedaily.com/releases/2008/12/081201100830.htm
World Journal of Gastroenterology. "What Is The Etiology Of Cardiac Syndrome X?." ScienceDaily. www.sciencedaily.com/releases/2008/12/081201100830.htm (accessed September 23, 2014).

Share This



More Health & Medicine News

Tuesday, September 23, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Ebola Costs Keep Mounting

Ebola Costs Keep Mounting

Reuters - Business Video Online (Sep. 23, 2014) The WHO has warned up to 20,000 people could be infected with Ebola over the next few weeks. As Sonia Legg reports, the implications for the West African countries suffering from the disease are huge. Video provided by Reuters
Powered by NewsLook.com
Ebola Cases Could Reach 1.4 Million Within 4 Months

Ebola Cases Could Reach 1.4 Million Within 4 Months

Newsy (Sep. 23, 2014) Health officials warn that without further intervention, the number of Ebola cases in Liberia and Sierra Leone could reach 1.4 million by January. Video provided by Newsy
Powered by NewsLook.com
WHO: Ebola Cases to Triple in Weeks Without Drastic Action

WHO: Ebola Cases to Triple in Weeks Without Drastic Action

AFP (Sep. 23, 2014) The number of Ebola infections will triple to 20,000 by November, soaring by thousands every week if efforts to stop the outbreak are not stepped up radically, the WHO warned in a study on Tuesday. Duration: 01:01 Video provided by AFP
Powered by NewsLook.com
5 Ways Men Can Prevent Most Heart Attacks

5 Ways Men Can Prevent Most Heart Attacks

Newsy (Sep. 23, 2014) No surprise here: A recent study says men can reduce their risk of heart attack by maintaining a healthy lifestyle, which includes daily exercise. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins