Featured Research

from universities, journals, and other organizations

Easier To Produce Drugs Using New Biosensor

Date:
December 13, 2008
Source:
Vetenskapsrådet (The Swedish Research Council)
Summary:
Scientists have developed a biosensor with an artificial membrane, which means that membrane-bound proteins can retain their natural structure and function. The method facilitates the study of the function of the proteins, which could be of major significance in the search for new drugs.

Chalmers researcher Andreas Dahlin has developed a biosensor with an artificial membrane, which means that membrane-bound proteins can retain their natural structure and function. The method facilitates the study of the function of the proteins, which could be of major significance in the search for new drugs.

Related Articles


One-third of all our proteins have the cell membrane as their natural environment, where they perform several of the most basic life-preserving biological processes. Approximately half of the most common drugs today are directed at membrane receptor proteins. Understanding membrane proteins is therefore vital in modern drug development.

The new biosensor is based on nanostructures which comprise holes in thin metal films where different types of membrane with membrane proteins can be formed. This makes it possible to analyse the features of the proteins, which are normally sensitive and unstable outside their natural environment. On Friday, December 12, Andreas Dahlin will defend his thesis.

"All processes which are being developed are spontaneous under the right conditions and take place 'by themselves'. The thesis also shows how biochemical reactions that take place in the membrane can be studied by measuring the colours on the nanostructured surface," he states.

The colour changes can be attributed to the local chemical environment on the nanostructured metal surface and provide information about different processes in which the proteins being studied are involved.

"Greater knowledge of the reactions in membrane proteins will lead to a greater understanding of how a drug functions, which will ultimately contribute to our ability to develop several drugs more rapidly," says Andreas Dahlin.

The colour phenomenon arises due to what are known as plasmons - heat wave movement that arises when light induces electrons to move in a fixed rhythm on a metal surface. The strong colours generated by plasmons have been utilised by people for thousands of years.

The first alchemists in China made elixir containing gold nanoparticles with a clear red colour and it was claimed that they had life-prolonging features. This type of alternative medicine exists even today. Another common example of plasmons is the clear colours found in mediaeval church windows.

A great deal of the work was carried out at the Department of Solid State Physics at Lund University. There has also been collaboration with the Department of Clinical Chemistry at Sahlgrenska University Hospital and with Duke University in Durham, USA.

Report Abstract: Nanoplasmonic Biosensors compatible with Artificial Cell Membranes


Story Source:

The above story is based on materials provided by Vetenskapsrådet (The Swedish Research Council). Note: Materials may be edited for content and length.


Cite This Page:

Vetenskapsrådet (The Swedish Research Council). "Easier To Produce Drugs Using New Biosensor." ScienceDaily. ScienceDaily, 13 December 2008. <www.sciencedaily.com/releases/2008/12/081209085727.htm>.
Vetenskapsrådet (The Swedish Research Council). (2008, December 13). Easier To Produce Drugs Using New Biosensor. ScienceDaily. Retrieved October 31, 2014 from www.sciencedaily.com/releases/2008/12/081209085727.htm
Vetenskapsrådet (The Swedish Research Council). "Easier To Produce Drugs Using New Biosensor." ScienceDaily. www.sciencedaily.com/releases/2008/12/081209085727.htm (accessed October 31, 2014).

Share This



More Matter & Energy News

Friday, October 31, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Jaguar Land Rover Opens $800 Million Factory in Britain

Jaguar Land Rover Opens $800 Million Factory in Britain

AFP (Oct. 30, 2014) — British luxury car manufacturer Jaguar Land Rover opened a $800 million engine manufacturing centre in western England, creating 1,400 jobs. Duration: 00:45 Video provided by AFP
Powered by NewsLook.com
SkyCruiser Concept Claims to Solve Problem With Flying Cars

SkyCruiser Concept Claims to Solve Problem With Flying Cars

Buzz60 (Oct. 30, 2014) — A start-up company called Krossblade says its SkyCruiser concept flying car solves the problem with most flying car concepts. Mara Montalbano (@maramontalbano) explains. Video provided by Buzz60
Powered by NewsLook.com
Mind-Controlled Prosthetic Arm Restores Amputee Dexterity

Mind-Controlled Prosthetic Arm Restores Amputee Dexterity

Reuters - Innovations Video Online (Oct. 29, 2014) — A Swedish amputee who became the first person to ever receive a brain controlled prosthetic arm is able to manipulate and handle delicate objects with an unprecedented level of dexterity. The device is connected directly to his bone, nerves and muscles, giving him the ability to control it with his thoughts. Matthew Stock reports. Video provided by Reuters
Powered by NewsLook.com
Robots Get Funky on the Dance Floor

Robots Get Funky on the Dance Floor

AP (Oct. 29, 2014) — Dancing, spinning and fighting robots are showing off their agility at "Robocomp" in Krakow. (Oct. 29) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:

Strange & Offbeat Stories

 

Space & Time

Matter & Energy

Computers & Math

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins