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Advance Toward First Saliva Test For Type 2 Diabetes

Date:
January 20, 2009
Source:
American Chemical Society
Summary:
Scientists in Oregon and India are reporting an advance toward developing the first saliva test to diagnose and monitor effectiveness of treatment for Type 2 diabetes. The number of cases of that disease (18 million in the United States alone) has doubled during the last 30 years in parallel with the epidemic of obesity.

Scientists in Oregon and India are reporting an advance toward developing the first saliva test to diagnose and monitor effectiveness of treatment for Type 2 diabetes. The number of cases of that disease (18 million in the United States alone) has doubled during the last 30 years in parallel with the epidemic of obesity.

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Researchers say their work represents the first comprehensive description of the proteins in the saliva of patients with Type 2 diabetes, also called non-insulin dependent diabetes.

In the study, Paturi V. Rao and colleagues note that early diagnosis and effective treatment is critical for preventing the disease's complications, including loss of vision, nerve damage, and kidney damage. One important barrier is the need for sometimes-painful needle sticks to draw blood for tests. The discomfort can discourage patients from properly monitoring their blood sugar levels, the scientists say.

The researchers analyzed saliva samples from individuals with and without Type 2 diabetes for protein biomarkers of diabetes. They identified 65 proteins that appeared twice as often in the diabetic samples than the non-diabetic samples. These newly identified proteins could lead to new, noninvasive tests for diabetes screening, detection, and monitoring, the researchers say.


Story Source:

The above story is based on materials provided by American Chemical Society. Note: Materials may be edited for content and length.


Journal Reference:

  1. Rao et al. Proteomic Identification of Salivary Biomarkers of Type-2 Diabetes. Journal of Proteome Research, 2009; 8 (1): 239 DOI: 10.1021/pr8003776

Cite This Page:

American Chemical Society. "Advance Toward First Saliva Test For Type 2 Diabetes." ScienceDaily. ScienceDaily, 20 January 2009. <www.sciencedaily.com/releases/2009/01/090119091615.htm>.
American Chemical Society. (2009, January 20). Advance Toward First Saliva Test For Type 2 Diabetes. ScienceDaily. Retrieved March 4, 2015 from www.sciencedaily.com/releases/2009/01/090119091615.htm
American Chemical Society. "Advance Toward First Saliva Test For Type 2 Diabetes." ScienceDaily. www.sciencedaily.com/releases/2009/01/090119091615.htm (accessed March 4, 2015).

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