Featured Research

from universities, journals, and other organizations

Injections Of Licorice Ingredient Show Promise As Treatment For Cocaine Addiction

Date:
February 20, 2009
Source:
American Chemical Society
Summary:
An ingredient in licorice shows promise as an antidote for the toxic effects of cocaine abuse, including deadly overdoses of the highly addictive drug, researchers are reporting.

An ingredient in licorice shows promise as an antidote for the toxic effects of cocaine abuse.
Credit: American Chemical Society

An ingredient in licorice shows promise as an antidote for the toxic effects of cocaine abuse, including deadly overdoses of the highly addictive drug, researchers in Korea and Pennsylvania are reporting.

Related Articles


In the new study, Meeyul Hwang, Chae Ha Yang, and colleagues note that there is currently no effective medicine for treating cocaine abuse or addiction. Recent animal studies conducted by the researchers show that a licorice ingredient called isoliquiritigenin (ISL) can block the nervous system’s production of dopamine. That neurotransmitter is involved in emotion, movement, and other brain activities.

Cocaine and other addictive drugs stimulate dopamine and help produce the pleasurable and addictive effects. Drugs that block dopamine block this response. The scientists used rats as model animals to show that rats injected with ISL just prior to cocaine-administration showed 50 percent less of the behavioral effects associated with the illicit drug.

They also showed that ISL injections protected nerve cells in the brain from cocaine-associated damage.


Story Source:

The above story is based on materials provided by American Chemical Society. Note: Materials may be edited for content and length.


Journal Reference:

  1. Jeon et al. Proteomic and Behavioral Analysis of Response to Isoliquiritigenin in Brains of Acute Cocaine Treated Rats. Journal of Proteome Research, 2008; 7 (12): 5094 DOI: 10.1021/pr800237s

Cite This Page:

American Chemical Society. "Injections Of Licorice Ingredient Show Promise As Treatment For Cocaine Addiction." ScienceDaily. ScienceDaily, 20 February 2009. <www.sciencedaily.com/releases/2009/02/090218223504.htm>.
American Chemical Society. (2009, February 20). Injections Of Licorice Ingredient Show Promise As Treatment For Cocaine Addiction. ScienceDaily. Retrieved October 24, 2014 from www.sciencedaily.com/releases/2009/02/090218223504.htm
American Chemical Society. "Injections Of Licorice Ingredient Show Promise As Treatment For Cocaine Addiction." ScienceDaily. www.sciencedaily.com/releases/2009/02/090218223504.htm (accessed October 24, 2014).

Share This



More Mind & Brain News

Friday, October 24, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Academic Scandal Shocks UNC

Academic Scandal Shocks UNC

AP (Oct. 23, 2014) A scandal involving bogus classes and inflated grades at the University of North Carolina was bigger than previously reported, a new investigation found. (Oct. 23) Video provided by AP
Powered by NewsLook.com
Working Mother Getaway: Beaches Turks & Caicos

Working Mother Getaway: Beaches Turks & Caicos

Working Mother (Oct. 22, 2014) Feast your eyes on this gorgeous family-friendly resort. Video provided by Working Mother
Powered by NewsLook.com
What Your Favorite Color Says About You

What Your Favorite Color Says About You

Buzz60 (Oct. 22, 2014) We all have one color we love to wear, and believe it or not, your color preference may reveal some of your character traits. In celebration of National Color Day, Krystin Goodwin (@kyrstingoodwin) highlights what your favorite colors may say about you. Video provided by Buzz60
Powered by NewsLook.com
First-Of-Its-Kind Treatment Gives Man Ability To Walk Again

First-Of-Its-Kind Treatment Gives Man Ability To Walk Again

Newsy (Oct. 21, 2014) A medical team has for the first time given a man the ability to walk again after transplanting cells from his brain onto his severed spinal cord. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins