Featured Research

from universities, journals, and other organizations

Shrinking In Hippocampus Area Of Brain Precedes Alzheimer's Disease

Date:
March 17, 2009
Source:
American Academy of Neurology
Summary:
People who have lost brain cells in the hippocampus area of the brain are more likely to develop dementia, according to a study in the journal Neurology.

People who have lost brain cells in the hippocampus area of the brain are more likely to develop dementia, according to a study published in the March 17, 2009, print issue of Neurology®, the medical journal of the American Academy of Neurology.

The study involved 64 people with Alzheimer's disease, 44 people with mild cognitive impairment, which is the stage of memory problems that precedes Alzheimer's disease, and 34 people with no memory or thinking problems.

MRI scans were performed on all of the participants at the beginning of the study and again an average of a year and a half later. During that time, 23 of the people with mild cognitive impairment had developed Alzheimer's disease, along with three of the healthy participants.

The researchers measured the volume of the whole brain and the hippocampus area, which is affected by Alzheimer's disease, at the beginning and end of the study, and calculated the rate of shrinkage in the brain over that time.

For the people who did not have dementia at the beginning of the study, those with smaller hippocampal volumes and higher rates of shrinkage were two to four times as likely to develop dementia as those with larger volumes and a slower rate of atrophy.

"This finding seems to reflect that at the stage of mild cognitive impairment, considerable atrophy has already occurred in the hippocampus," said study author Wouter Henneman, MD, of VU University Medical Center in Amsterdam, The Netherlands. "In people who already have Alzheimer's disease, the loss of nerve cells is more widespread throughout the brain."


Story Source:

The above story is based on materials provided by American Academy of Neurology. Note: Materials may be edited for content and length.


Cite This Page:

American Academy of Neurology. "Shrinking In Hippocampus Area Of Brain Precedes Alzheimer's Disease." ScienceDaily. ScienceDaily, 17 March 2009. <www.sciencedaily.com/releases/2009/03/090316173214.htm>.
American Academy of Neurology. (2009, March 17). Shrinking In Hippocampus Area Of Brain Precedes Alzheimer's Disease. ScienceDaily. Retrieved July 24, 2014 from www.sciencedaily.com/releases/2009/03/090316173214.htm
American Academy of Neurology. "Shrinking In Hippocampus Area Of Brain Precedes Alzheimer's Disease." ScienceDaily. www.sciencedaily.com/releases/2009/03/090316173214.htm (accessed July 24, 2014).

Share This




More Mind & Brain News

Thursday, July 24, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

New Painkiller Designed To Discourage Abuse: Will It Work?

New Painkiller Designed To Discourage Abuse: Will It Work?

Newsy (July 24, 2014) — The FDA approved Targiniq ER on Wednesday, a painkiller designed to keep users from abusing it. Like any new medication, however, it has doubters. Video provided by Newsy
Powered by NewsLook.com
China's Ageing Millions Look Forward to Bleak Future

China's Ageing Millions Look Forward to Bleak Future

AFP (July 24, 2014) — China's elderly population is expanding so quickly that children struggle to look after them, pushing them to do something unexpected in Chinese society- move their parents into a nursing home. Duration: 02:07 Video provided by AFP
Powered by NewsLook.com
Idaho Boy Helps Brother With Disabilities Complete Triathlon

Idaho Boy Helps Brother With Disabilities Complete Triathlon

Newsy (July 23, 2014) — An 8-year-old boy helped his younger brother, who has a rare genetic condition that's confined him to a wheelchair, finish a triathlon. Video provided by Newsy
Powered by NewsLook.com
Huge Schizophrenia Study Finds Dozens Of New Genetic Causes

Huge Schizophrenia Study Finds Dozens Of New Genetic Causes

Newsy (July 22, 2014) — The 83 new genetic markers could open dozens of new avenues for schizophrenia treatment research. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins