Featured Research

from universities, journals, and other organizations

Scientists Discover Why A Low GI Meal Makes You Feel Full

Date:
March 18, 2009
Source:
Society for Endocrinology
Summary:
Eating a meal with a low GI (glycemic index) increases gut hormone production which leads to suppression of appetite and the feeling of fullness. Researchers studied the effects of a low versus high GI meal on levels of gut hormones. This is the first study to provide clues as to how a low GI meal produces satiety.

Eating a meal with a low GI (glycaemic index) increases gut hormone production which leads to suppression of appetite and the feeling of fullness.

This is the finding of new research being presented at the annual Society for Endocrinology BES meeting in Harrogate.

Researchers from King’s College London studied the effects of a low versus high GI meal on levels of gut hormones.  This is the first study to provide clues as to how a low GI meal produces satiety.

GI is a ranking assigned to carbohydrates according to their effect on the body’s blood sugar levels. A low GI meal takes longer to digest and releases sugar into the bloodstream more slowly than a high GI meal.  High GI foods include white bread, croissants and cornflakes, whereas granary bread, milk and most fruit and vegetables are all classed as low GI foods.

A low GI diet is known to cause reduced appetite(1) but the mechanisms behind this have so far remained unknown.  To address this, Dr Reza Norouzy and colleagues at King’s College London looked at the effects of a single low versus high GI meal on gut hormone levels in twelve healthy volunteers.  Each participant ate an identical medium GI meal for dinner, fasted overnight, and was given either a low (46) or high (66) GI meal for breakfast.  Blood samples were then taken every 30 minutes for 150 minutes, and levels of the gut hormone glucagon-like peptide 1 (GLP-1) and insulin measured.  GLP-1 is a hormone produced by the gut that has been shown to cause a feeling of fullness and suppression of appetite(2). 

Volunteers who ate a low GI breakfast had 20% higher blood plasma levels of GLP-1 (area under curve = 4839±1831) and 38% lower levels of insulin (10088±4757), compared to those who had consumed a high GI breakfast (3865±1630 and 16245±7600 respectively).  These results show for the first time that eating a low GI meal increases GLP-1 production and suggest a physiological mechanism as to why a low GI meal makes you feel fuller than a high GI meal.

Researcher Dr Reza Norouzy said:

“Our results show for the first time the direct effect of a single GI meal on gut hormone levels.  We already know that the hormone GLP-1 and a low GI meal independently lead to suppression of appetite.  This study builds on these findings by providing a physiological mechanism to explain how a low GI meal makes you feel fuller than a high GI meal.  GLP-1 is one of the most potent hormones for suppressing appetite.  Our results suggest that low GI meals lead to a feeling of fullness because of increased levels of GLP-1 in the bloodstream.  This is an exciting result which provides further clues about how our appetite is regulated, and offers an insight into how a low GI diet produces satiety.  This is a preliminary study that only involved a small number of people.   We now need expand these findings and look at the effects of low versus high GI meals in a larger cohort of people.”


Story Source:

The above story is based on materials provided by Society for Endocrinology. Note: Materials may be edited for content and length.


Cite This Page:

Society for Endocrinology. "Scientists Discover Why A Low GI Meal Makes You Feel Full." ScienceDaily. ScienceDaily, 18 March 2009. <www.sciencedaily.com/releases/2009/03/090317201139.htm>.
Society for Endocrinology. (2009, March 18). Scientists Discover Why A Low GI Meal Makes You Feel Full. ScienceDaily. Retrieved July 25, 2014 from www.sciencedaily.com/releases/2009/03/090317201139.htm
Society for Endocrinology. "Scientists Discover Why A Low GI Meal Makes You Feel Full." ScienceDaily. www.sciencedaily.com/releases/2009/03/090317201139.htm (accessed July 25, 2014).

Share This




More Health & Medicine News

Friday, July 25, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Beatings and Addiction: Pakistan Drug 'clinic' Tortures Patients

Beatings and Addiction: Pakistan Drug 'clinic' Tortures Patients

AFP (July 24, 2014) — A so-called drugs rehab 'clinic' is closed down in Pakistan after police find scores of ‘patients’ chained up alleging serial abuse. Duration 03:05 Video provided by AFP
Powered by NewsLook.com
Too Few Teens Receiving HPV Vaccination, CDC Says

Too Few Teens Receiving HPV Vaccination, CDC Says

Newsy (July 24, 2014) — The Centers for Disease Control and Prevention is blaming doctors for the low number of children being vaccinated for HPV. Video provided by Newsy
Powered by NewsLook.com
New Painkiller Designed To Discourage Abuse: Will It Work?

New Painkiller Designed To Discourage Abuse: Will It Work?

Newsy (July 24, 2014) — The FDA approved Targiniq ER on Wednesday, a painkiller designed to keep users from abusing it. Like any new medication, however, it has doubters. Video provided by Newsy
Powered by NewsLook.com
Doctor At Forefront Of Fighting Ebola Outbreak Gets Ebola

Doctor At Forefront Of Fighting Ebola Outbreak Gets Ebola

Newsy (July 24, 2014) — Sheik Umar Khan has treated many of the people infected in the Ebola outbreak, and now he's become one of them. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

    Health News

      Environment News

        Technology News



          Save/Print:
          Share:  

          Free Subscriptions


          Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

          Get Social & Mobile


          Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

          Have Feedback?


          Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
          Mobile iPhone Android Web
          Follow Facebook Twitter Google+
          Subscribe RSS Feeds Email Newsletters
          Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins