Featured Research

from universities, journals, and other organizations

Eating Soy Early In Life May Reduce Breast Cancer Among Asian Women

Date:
March 27, 2009
Source:
American Association for Cancer Research
Summary:
Asian-American women who ate higher amounts of soy during childhood had a 58 percent reduced risk of breast cancer, according to a new study.

Asian-American women who ate higher amounts of soy during childhood had a 58 percent reduced risk of breast cancer, according to a study published in Cancer Epidemiology, Biomarkers and Prevention, a journal of the American Association for Cancer Research.

"Historically, breast cancer incidence rates have been four to seven times higher among white women in the U.S. than in women in China or Japan. However, when Asian women migrate to the U.S., their breast cancer risk rises over several generations and reaches that of U.S. white women, suggesting that modifiable factors, rather than genetics, are responsible for the international differences. These lifestyle or environmental factors remain elusive; our study was designed to identify them," said Regina Ziegler, Ph.D., M.P.H., a senior investigator in the NCI Division of Cancer Epidemiology and Genetics (DCEG).

The current study focused on women of Chinese, Japanese and Filipino descent who were living in San Francisco, Oakland, Los Angeles or Hawaii. Researchers interviewed 597 women with breast cancer and 966 healthy women. If the women had mothers living in the United States, researchers interviewed those mothers to determine the frequency of soy consumption in childhood.

Researchers divided soy intake into thirds and compared the highest and lowest groups. High intake of soy in childhood was associated with a 58 percent reduction in breast cancer. A high level of soy intake in the adolescent and adult years was associated with a 20 to 25 percent reduction. The childhood relationship held in all three races and all three study sites, and in women with and without a family history of breast cancer. "Since the effects of childhood soy intake could not be explained by measures other than Asian lifestyle during childhood or adult life, early soy intake might itself be protective," said the study's lead investigator, Larissa Korde, M.D., M.P.H., a staff clinician at the NCI's Clinical Genetics Branch.

"Childhood soy intake was significantly associated with reduced breast cancer risk in our study, suggesting that the timing of soy intake may be especially critical," said Korde. The underlying mechanism is not known. Korde said her study suggests that early soy intake may have a biological role in breast cancer prevention. "Soy isoflavones have estrogenic properties that may cause changes in breast tissue. Animal models suggest that ingestion of soy may result in earlier maturation of breast tissue and increased resistance to carcinogens."

As provocative as the findings are, Ziegler cautioned that it would be premature to recommend changes in childhood diet. "This is the first study to evaluate childhood soy intake and subsequent breast cancer risk, and this one result is not enough for a public health recommendation," she said. "The findings need to be replicated through additional research."


Story Source:

The above story is based on materials provided by American Association for Cancer Research. Note: Materials may be edited for content and length.


Journal Reference:

  1. Larissa A. Korde, Anna H. Wu, Thomas Fears, Abraham M.Y. Nomura, Dee W. West, Laurence N. Kolonel, Malcolm C. Pike, Robert N. Hoover, and Regina G. Ziegler. Childhood Soy Intake and Breast Cancer Risk in Asian American Women. Cancer Epidemiology, Biomarkers and Prevention, 2009; DOI: 10.1158/1055-9965.EPI-08-0405

Cite This Page:

American Association for Cancer Research. "Eating Soy Early In Life May Reduce Breast Cancer Among Asian Women." ScienceDaily. ScienceDaily, 27 March 2009. <www.sciencedaily.com/releases/2009/03/090324131442.htm>.
American Association for Cancer Research. (2009, March 27). Eating Soy Early In Life May Reduce Breast Cancer Among Asian Women. ScienceDaily. Retrieved September 21, 2014 from www.sciencedaily.com/releases/2009/03/090324131442.htm
American Association for Cancer Research. "Eating Soy Early In Life May Reduce Breast Cancer Among Asian Women." ScienceDaily. www.sciencedaily.com/releases/2009/03/090324131442.htm (accessed September 21, 2014).

Share This



More Health & Medicine News

Sunday, September 21, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Sierra Leone's Nationwide Ebola Curfew Underway

Sierra Leone's Nationwide Ebola Curfew Underway

Newsy (Sep. 20, 2014) Sierra Leone is locked down as aid workers and volunteers look for new cases of Ebola. Video provided by Newsy
Powered by NewsLook.com
Changes Found In Brain After One Dose Of Antidepressants

Changes Found In Brain After One Dose Of Antidepressants

Newsy (Sep. 19, 2014) A study suggest antidepressants can kick in much sooner than previously thought. Video provided by Newsy
Powered by NewsLook.com
Could Grief Affect The Immune Systems Of Senior Citizens?

Could Grief Affect The Immune Systems Of Senior Citizens?

Newsy (Sep. 19, 2014) The study found elderly people are much more likely to become susceptible to infection than younger adults going though a similar situation. Video provided by Newsy
Powered by NewsLook.com
Jury Delivers Verdict in Salmonella Trial

Jury Delivers Verdict in Salmonella Trial

AP (Sep. 19, 2014) A federal jury has convicted three people in connection with an outbreak of salmonella poisoning five years ago that sickened hundreds of people and was linked to a number of deaths. (Sept. 19) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins