Featured Research

from universities, journals, and other organizations

Can Kidney Disease Cause Cancer?

Date:
May 6, 2009
Source:
American Society of Nephrology
Summary:
Moderate kidney disease increases an older man's risk of developing certain cancers, according to a new study. Given that chronic kidney disease affects about a third of older men, maintaining kidney function could help prevent cancer in the general population.

Moderate kidney disease increases an older man's risk of developing certain cancers, according to a new study. Given that chronic kidney disease (CKD) affects about a third of older men, maintaining kidney function could help prevent cancer in the general population.

People with end-stage renal disease (ESRD) and kidney transplant recipients are at increased risk of developing cancer, but little is known about the cancer risks of individuals with milder kidney dysfunction. To investigate, Germaine Wong, MD (Children's Hospital at Westmead, Australia), and her colleagues studied data from 3654 Australians aged 49 to 97 years who were followed for an average of 10 years. They observed individuals who had decreased kidney function for an increased risk of developing cancer.

The researchers discovered that men with moderate kidney dysfunction had a 39% increased risk of developing cancer over the risk seen in men with normal kidney function. Risk increased as kidney function declined, and men with significant kidney dysfunction had a three-fold increased risk above normal. The risk for lung and urinary tract cancers, but not prostate cancer, was higher among men with kidney disease.

Some evidence suggests that inflammation caused by CKD may contribute to the development of cancer. Other studies have found an association between Vitamin D deficiency, which is highly prevalent among people with moderately reduced kidney function, and increased cancer risk. Additional research is needed to uncover the underlying mechanisms involved in the cancer-kidney disease link found in this study and to explain why a link was not found in women.

According to Dr. Wong, "Men with CKD should be aware of cancer prevention and screening for early detection," she said. "CKD prevention may be a worthwhile strategy for preventing and reducing cancer risk in the general population."

Dr. Wong reports no financial disclosures.


Story Source:

The above story is based on materials provided by American Society of Nephrology. Note: Materials may be edited for content and length.


Journal Reference:

  1. Association of CKD and Cancer Risk in Older People. Journal of the American Society Nephrology, April 30, 2009 DOI: 10.1681/ASN.2008090998

Cite This Page:

American Society of Nephrology. "Can Kidney Disease Cause Cancer?." ScienceDaily. ScienceDaily, 6 May 2009. <www.sciencedaily.com/releases/2009/04/090430172938.htm>.
American Society of Nephrology. (2009, May 6). Can Kidney Disease Cause Cancer?. ScienceDaily. Retrieved September 17, 2014 from www.sciencedaily.com/releases/2009/04/090430172938.htm
American Society of Nephrology. "Can Kidney Disease Cause Cancer?." ScienceDaily. www.sciencedaily.com/releases/2009/04/090430172938.htm (accessed September 17, 2014).

Share This



More Health & Medicine News

Wednesday, September 17, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Obesity Rates Steady Even As Americans' Waistlines Expand

Obesity Rates Steady Even As Americans' Waistlines Expand

Newsy (Sep. 17, 2014) Researchers are puzzled as to why obesity rates remain relatively stable as average waistlines continue to expand. Video provided by Newsy
Powered by NewsLook.com
President To Send 3,000 Military Personnel To Fight Ebola

President To Send 3,000 Military Personnel To Fight Ebola

Newsy (Sep. 16, 2014) President Obama is expected to send 3,000 troops to West Africa as part of the effort to contain Ebola's spread. Video provided by Newsy
Powered by NewsLook.com
Obama Orders Military Response to Ebola

Obama Orders Military Response to Ebola

AP (Sep. 16, 2014) Calling the Ebola outbreak in West Africa a potential threat to global security, President Barack Obama is ordering 3,000 U.S. military personnel to the stricken region amid worries that the outbreak is spiraling out of control. (Sept. 16) Video provided by AP
Powered by NewsLook.com
UN: 20,000 Could Be Infected With Ebola by Year End

UN: 20,000 Could Be Infected With Ebola by Year End

AFP (Sep. 16, 2014) Nearly $1.0 billion dollars is needed to fight the Ebola outbreak raging in west Africa, the United Nations say, warning that 20,000 could be infected by year end. Duration: 00:40 Video provided by AFP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins