Featured Research

from universities, journals, and other organizations

Physiological Response May Explain Why Some Severely Obese Patients Overeat

Date:
June 10, 2009
Source:
Lifespan
Summary:
Severely obese adults respond more slowly to repeated food exposure than normal weight individuals. Delayed response is linked to reduced rates of satiation, or fullness, during a meal. This study is first of its kind to compare severely obese patient and normal weight individuals.

Don't feel like you are getting full when eating a large meal? New research from The Miriam Hospital suggests that a physiological response may partially explain why severely obese individuals may not feel satisfied after eating and often have difficulty controlling the amount of food they consume during a meal.

Related Articles


Researchers led by Dale Bond, PhD, of The Miriam Hospital's Weight Control and Diabetes Research Center focused on habituation, or the idea that continual exposure to a specific food decreases one's physical response to that food. Habituation theory suggests that if one habituates, or adjusts, slowly to food cues, they are less likely to feel satisfied with that particular food and can consume more of it.

In the study, published online in Obesity Surgery, the research team looked at saliva production following repeated exposure to lemon juice. They compared the responses of two groups – severely obese patients preparing for bariatric surgery and normal weight individuals – and found that the bariatric surgery candidates continued to salivate at a consistent rate throughout the tastings, indicating that very little habituation occurred. Meanwhile, the salivation rate of the normal weight controls decreased with successive exposures to the lemon juice.

"The failure of bariatric surgery candidates to habituate suggests that satiation, or the feeling of fullness while eating, is impaired in this population. This could play a role in the inability of some severely obese individuals to regulate or control the amount of food that they eat during a meal," says Bond.

He adds that the findings make a case for the use of habituation as a model to study why some patients who have undergone bariatric surgery continue to engage in problematic behaviors, such as binge eating, which contributes to poorer weight loss outcomes.

The study included 34 severely obese bariatric surgery candidates and 18 individuals of normal weight. Saliva was collected from cotton balls positioned in each participant's mouth during two baseline water trials and ten lemon juice trials. Participants also completed questionnaires to assess the level of conscious control over eating as well as the frequency of binge eating episodes during the previous 28 days.

Although the study's findings support previous research comparing individuals with mild obesity and normal weight individuals, the researchers say this is the first study to test this model in a severely obese patient population.

"Bariatric surgery has been referred to as 'behavioral surgery,' given the importance of eating behavior in postoperative outcomes. Habituation may be a valuable tool for enhancing our understanding of eating regulation in severely obese individuals and how it is impacted by bariatric surgery," says Bond, who is also an assistant professor (research) in psychiatry (weight control) at The Warren Alpert Medical School of Brown University.

The authors add that further research is needed to determine whether habituation rates to food stimuli change after bariatric surgery and whether such changes are related to weight loss and/or mechanisms specific to different surgical procedures.

The research was funded by grants from Alpert Medical School's Center for Excellence in Women's Health and the American Diabetes Association. Study co-authors were Rena R. Wing, Harry C. Sax and Sivamainthan Vithiananthan, all from The Miriam Hospital and Alpert Medical School; G.D. Roye and Beth A. Ryder from Rhode Island Hospital and Alpert Medical School; Dieter Pohl from Roger Williams Hospital; and Hollie A. Raynor from the University of Tennessee.


Story Source:

The above story is based on materials provided by Lifespan. Note: Materials may be edited for content and length.


Cite This Page:

Lifespan. "Physiological Response May Explain Why Some Severely Obese Patients Overeat." ScienceDaily. ScienceDaily, 10 June 2009. <www.sciencedaily.com/releases/2009/06/090609130806.htm>.
Lifespan. (2009, June 10). Physiological Response May Explain Why Some Severely Obese Patients Overeat. ScienceDaily. Retrieved November 28, 2014 from www.sciencedaily.com/releases/2009/06/090609130806.htm
Lifespan. "Physiological Response May Explain Why Some Severely Obese Patients Overeat." ScienceDaily. www.sciencedaily.com/releases/2009/06/090609130806.htm (accessed November 28, 2014).

Share This


More From ScienceDaily



More Health & Medicine News

Friday, November 28, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Rural India's Low-Cost Sanitary Pad Revolution

Rural India's Low-Cost Sanitary Pad Revolution

AFP (Nov. 28, 2014) — One man hopes his invention -– a machine that produces cheap sanitary pads –- will help empower Indian women. Duration: 01:51 Video provided by AFP
Powered by NewsLook.com
Research on Bats Could Help Develop Drugs Against Ebola

Research on Bats Could Help Develop Drugs Against Ebola

AFP (Nov. 28, 2014) — In Africa's only biosafety level 4 laboratory, scientists have been carrying out experiments on bats to understand how virus like Ebola are being transmitted, and how some of them resist to it. Duration: 01:18 Video provided by AFP
Powered by NewsLook.com
Ebola Leaves Orphans Alone in Sierra Leone

Ebola Leaves Orphans Alone in Sierra Leone

AFP (Nov. 27, 2014) — The Ebola epidemic sweeping Sierra Leone is having a profound effect on the country's children, many of whom have been left without any family members to support them. Duration: 01:02 Video provided by AFP
Powered by NewsLook.com
Experimental Ebola Vaccine Shows Promise In Human Trial

Experimental Ebola Vaccine Shows Promise In Human Trial

Newsy (Nov. 27, 2014) — A recent test of a prototype Ebola vaccine generated an immune response to the disease in subjects. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:

Strange & Offbeat Stories

 

Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins