Featured Research

from universities, journals, and other organizations

New Chemistry Techniques Improve Hybrid Scanner Performance

Date:
June 15, 2009
Source:
Society of Nuclear Medicine
Summary:
A new PET/MR imaging system has been developed that can successfully provide whole-body images of rats and other small animals, according to researchers.

A new PET/MR imaging system has been developed that can successfully provide whole-body images of rats and other small animals, according to researchers at SNM's 56th Annual Meeting in Toronto. The new system could greatly improve imaging capabilities and advance research in many areas.

Related Articles


"Our system shows great promise because it is able to simultaneously provide the complementary strengths of PET and MRI in imaging rats and small animals," said Mitsuaki Tatsumi, associate professor of radiology at Osaka University Graduate School of Medicine and Medical Hospital, Osaka, Japan. "This ability opens up exciting new opportunities in research in terms of increased understanding of kinetics, biodistribution of radiopharmaceuticals and, eventually, disease characteristics and physiological processes. Next steps include imaging body tumors in rats or mice and developing PET/MRI systems that can image people."

A combined PET/MRI system delivers specific molecular information related to cell surface reactors, enzymes and gene expression that PET provides as well as important anatomical data, soft-tissue contrast and information about perfusion and permeability shown in MRI—at the same time.

The new combined PET/MRI system is a step forward from previous combined systems because it can image the bodies of rats and mice rather than just the brains. The system consists of depth-of-interaction block detectors and a permanent magnet for MRI.

In the study, researchers injected rats with the radionuclide C-11 methionine for PET imaging and with Gadoxetate for contrast MRI imaging. Simultaneous PET and MR imaging was performed from head to abdomen. PET, MR and co-registered fusion images were then evaluated for image quality.

The simultaneous PET/MRI system provided quality images in spite of the short half-life of C-11. The images showed excellent mapping of the liver and kidneys. C-11 methionine is known to accumulate in the pancreas, but it would have been difficult to image without clear mapping MR images. The use of Gadoextate as a contrast agent enhanced the power of the integrated PET/MRI system.


Story Source:

The above story is based on materials provided by Society of Nuclear Medicine. Note: Materials may be edited for content and length.


Cite This Page:

Society of Nuclear Medicine. "New Chemistry Techniques Improve Hybrid Scanner Performance." ScienceDaily. ScienceDaily, 15 June 2009. <www.sciencedaily.com/releases/2009/06/090615144331.htm>.
Society of Nuclear Medicine. (2009, June 15). New Chemistry Techniques Improve Hybrid Scanner Performance. ScienceDaily. Retrieved October 31, 2014 from www.sciencedaily.com/releases/2009/06/090615144331.htm
Society of Nuclear Medicine. "New Chemistry Techniques Improve Hybrid Scanner Performance." ScienceDaily. www.sciencedaily.com/releases/2009/06/090615144331.htm (accessed October 31, 2014).

Share This



More Health & Medicine News

Friday, October 31, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

U.S. Ebola Response Measures Demonstrated

U.S. Ebola Response Measures Demonstrated

AP (Oct. 31, 2014) Officials in the Washington area showed off Ebola response measures being taken at Dulles International Airport and the National Institutes of Health. (Oct. 31) Video provided by AP
Powered by NewsLook.com
Fauci Says Ebola Risk in US "essentially Zero"

Fauci Says Ebola Risk in US "essentially Zero"

AP (Oct. 30, 2014) NIAID Director Anthony Fauci said the risk of Ebola becoming an epidemic in the U.S. is essentially zero Thursday at the Washington Ideas Forum. He also said an Ebola vaccine will be tested in West Africa in the next few months. (Oct. 30) Video provided by AP
Powered by NewsLook.com
Nurse Defies Ebola Quarantine With Bike Ride

Nurse Defies Ebola Quarantine With Bike Ride

AP (Oct. 30, 2014) A nurse who vowed to defy Maine's voluntary quarantine for health care workers who treated Ebola patients followed through on her promise Thursday, leaving her home for an hour-long bike ride. (Oct. 30) Video provided by AP
Powered by NewsLook.com
Pot-Infused Edibles Raise Concerns in Colorado

Pot-Infused Edibles Raise Concerns in Colorado

AFP (Oct. 30, 2014) Colorado may have legalized marijuana for recreational use, but the debate around the decision still continues, with a recent - failed - attempt to ban cannabis-infused edibles. Duration: 01:53 Video provided by AFP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins