Featured Research

from universities, journals, and other organizations

Surgery Remains An Option For Advanced Lung Cancer

Date:
July 28, 2009
Source:
Loyola University Health System
Summary:
Oncologists have debated whether patients with a certain type of advanced lung cancer would benefit from surgery. Now a major study has found that surgery can significantly prolong survival without progression of the cancer, but does not dramatically improve overall survival.

In recent years, oncologists have debated whether patients with a certain type of advanced lung cancer would benefit from surgery.

Now a major study published in the journal The Lancet has found that surgery after standard chemotherapy and radiation can be an option for patients. Surgery significantly prolongs survival without progression of the lung cancer, but does not dramatically improve overall survival compared to a control group treated with conventional chemotherapy and radiation alone.

The patients who did appear to have a major benefit from surgery were those in whom a section of the lung (lobe) was removed, rather than the entire lung, lead author Dr. Kathy Albain and colleagues reported. Albain is a lung and breast cancer specialist at Loyola University Health System's Cardinal Bernardin Cancer Center.

"This the first study conducted in this group of patients where the only difference in the two groups of patients was the use of surgery," Albain said.

In an accompanying editorial, German researcher Dr. Wilfried Eberhardt and colleagues wrote that as a result of the new study, "We now have clear arguments in favor of surgery in well-selected patient subsets."

The study included patients with non-small cell cancer, which accounts for about 80 percent of all lung cancers. Patients had stage 3 cancer, in which the cancer had spread to lymph nodes in the center of the chest. This type of stage 3 cancer accounts for about 30 percent of all non-small cell lung cancer cases. Patients were treated at multiple academic and community hospitals in the United States and Canada.

One group of 202 patients was randomly assigned to receive surgery plus chemotherapy and radiation, while a second group of 194 patients received just chemotherapy and radiation.

Median overall survival was similar between the two groups: 23.6 months in the surgery group and 22.2 months in the non-surgery group. After five years, 37 patients in the surgical group and 24 patients in the non-surgery group were still alive. The median length of time it took before the cancer began to progress again after treatment was 12.8 months in the surgery group and 10.5 months in the non-surgery group.

"Another important finding of our study is that both groups of patients lived longer than previously reporter for this stage of the disease," Albain said. "This highlights the importance of multidisciplinary evaluation and treatment -- which all patients deserve."

Albain is a professor in the Department of Medicine, Division of Hematology/Oncology, Loyola University Chicago Stritch School of Medicine.


Story Source:

The above story is based on materials provided by Loyola University Health System. Note: Materials may be edited for content and length.


Cite This Page:

Loyola University Health System. "Surgery Remains An Option For Advanced Lung Cancer." ScienceDaily. ScienceDaily, 28 July 2009. <www.sciencedaily.com/releases/2009/07/090727080557.htm>.
Loyola University Health System. (2009, July 28). Surgery Remains An Option For Advanced Lung Cancer. ScienceDaily. Retrieved July 29, 2014 from www.sciencedaily.com/releases/2009/07/090727080557.htm
Loyola University Health System. "Surgery Remains An Option For Advanced Lung Cancer." ScienceDaily. www.sciencedaily.com/releases/2009/07/090727080557.htm (accessed July 29, 2014).

Share This




More Health & Medicine News

Tuesday, July 29, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Deadly Ebola Virus Threatens West Africa

Deadly Ebola Virus Threatens West Africa

AP (July 28, 2014) West African nations and international health organizations are working to contain the largest Ebola outbreak in history. It's one of the deadliest diseases known to man, but the CDC says it's unlikely to spread in the U.S. (July 28) Video provided by AP
Powered by NewsLook.com
$15B Deal on Vets' Health Care Reached

$15B Deal on Vets' Health Care Reached

AP (July 28, 2014) A bipartisan deal to improve veterans health care would authorize at least $15 billion in emergency spending to fix a veterans program scandalized by long patient wait times and falsified records. (July 28) Video provided by AP
Powered by NewsLook.com
Two Americans Contract Ebola in Liberia

Two Americans Contract Ebola in Liberia

Reuters - US Online Video (July 28, 2014) Two American aid workers in Liberia test positive for Ebola while working to combat the deadliest outbreak of the virus ever. Linda So reports. Video provided by Reuters
Powered by NewsLook.com
Traditional African Dishes Teach Healthy Eating

Traditional African Dishes Teach Healthy Eating

AP (July 28, 2014) Classes are being offered nationwide to encourage African Americans to learn about cooking fresh foods based on traditional African cuisine. The program is trying to combat obesity, heart disease and other ailments often linked to diet. (July 28) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins