Featured Research

from universities, journals, and other organizations

Early, Aggressive Treatment Recommended For Critically Ill Patients With Hematological Malignancy

Date:
September 2, 2009
Source:
BioMed Central
Summary:
A study of 7,689 admissions from 178 adult intensive care units in England, Wales and Northern Ireland has revealed the factors associated with a higher mortality rate in hematological malignancy. Researchers found that certain factors have a significant impact on the risk of death.

A study of 7,689 admissions from 178 adult intensive care units in England, Wales and Northern Ireland has revealed the factors associated with a higher mortality rate in haematological malignancy. Researchers writing in the journal Critical Care found that certain factors have a significant impact on the risk of death.

Haematological malignancy refers to a range of conditions resulting from the malignant transformation of bone marrow cells. Dr. Peter Hampshire, from Glan Clwyd Hospital, North Wales, worked with a team of researchers from the UK Intensive Care National Audit and Research Centre (ICNARC) Case Mix Programme Database to analyse high quality data from a 12-year period, relating admission characteristics to outcome in critically ill patients with haematological malignancy.

Intensive care unit mortality was 43.1% (3312 deaths) and acute hospital mortality was 59.2% (4239 deaths). Mortality increased with the number of organ failures on admission. Factors associated with an increased risk of death included bone marrow transplantation, Hodgkin's lymphoma, severe sepsis, age, a low haematocrit and length of hospital stay before intensive care admission. Artificial ventilation, however, was not associated with increased mortality, in contrast to previous studies.

Dr Hampshire said, "Historically these patients have had a very high mortality if they become sick enough to need intensive care. We conclude that, if appropriate, such patients should be treated aggressively with early intensive care unit admission".


Story Source:

The above story is based on materials provided by BioMed Central. Note: Materials may be edited for content and length.


Journal Reference:

  1. Peter A Hampshire, Catherine A Welch, Lawrence A McCrossan, Katharine Francis and David A Harrison. Admission factors associated with hospital mortality in patients with haematological malignancy admitted to UK adult, general Critical Care units: a secondary analysis of the ICNARC Case Mix Programme Database. Critical Care, (in press)

Cite This Page:

BioMed Central. "Early, Aggressive Treatment Recommended For Critically Ill Patients With Hematological Malignancy." ScienceDaily. ScienceDaily, 2 September 2009. <www.sciencedaily.com/releases/2009/08/090824204116.htm>.
BioMed Central. (2009, September 2). Early, Aggressive Treatment Recommended For Critically Ill Patients With Hematological Malignancy. ScienceDaily. Retrieved April 19, 2014 from www.sciencedaily.com/releases/2009/08/090824204116.htm
BioMed Central. "Early, Aggressive Treatment Recommended For Critically Ill Patients With Hematological Malignancy." ScienceDaily. www.sciencedaily.com/releases/2009/08/090824204116.htm (accessed April 19, 2014).

Share This



More Health & Medicine News

Saturday, April 19, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

'Holy Grail' Of Weight Loss? New Find Could Be It

'Holy Grail' Of Weight Loss? New Find Could Be It

Newsy (Apr. 18, 2014) In a potential breakthrough for future obesity treatments, scientists have used MRI scans to pinpoint brown fat in a living adult for the first time. Video provided by Newsy
Powered by NewsLook.com
Little Progress Made In Fighting Food Poisoning, CDC Says

Little Progress Made In Fighting Food Poisoning, CDC Says

Newsy (Apr. 18, 2014) A new report shows rates of two foodborne infections increased in the U.S. in recent years, while salmonella actually dropped 9 percent. Video provided by Newsy
Powered by NewsLook.com
Scientists Create Stem Cells From Adult Skin Cells

Scientists Create Stem Cells From Adult Skin Cells

Newsy (Apr. 17, 2014) The breakthrough could mean a cure for some serious diseases and even the possibility of human cloning, but it's all still a way off. Video provided by Newsy
Powered by NewsLook.com
Obama: 8 Million Healthcare Signups

Obama: 8 Million Healthcare Signups

AP (Apr. 17, 2014) President Barack Obama gave a briefing Thursday announcing 8 million people have signed up under the Affordable Care Act. He blasted continued Republican efforts to repeal the law. (April 17) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins