Featured Research

from universities, journals, and other organizations

Image-guided Radiation Therapy May Improve Outcomes For Obese Prostate Cancer Patients

Date:
September 3, 2009
Source:
American Society for Radiation Oncology
Summary:
Moderately to severely obese prostate cancer patients may have improved treatment outcomes when treated with image-guided radiation therapy (IGRT) over traditional external beam radiation therapy (EBRT) because IGRT corrects for prostate shifts, which, if not planned for, can lead to incorrect doses of radiation to the disease site, according to a new study.

Moderately to severely obese prostate cancer patients may have improved treatment outcomes when treated with image-guided radiation therapy (IGRT) over traditional external beam radiation therapy (EBRT) because IGRT corrects for prostate shifts, which, if not planned for, can lead to incorrect doses of radiation to the disease site, according to a study in the September 1 issue of the International Journal of Radiation Oncology*Biology*Physics, the official journal of the American Society for Radiation Oncology (ASTRO).

Several studies have suggested that obesity can lead to higher rates of clinical recurrence or biochemical failure rates in prostate cancer patients receiving EBRT. Researchers at the Carol G. Simon Cancer Center, Morristown Memorial Hospital in Morristown, N.J., and the Uematsu-Atsuchi-Serendipity Oncology Center in Terukuni, Kagoshima, Japan, sought to determine if these failure rates were caused by the treatment modality used rather than strictly the fact that the patients were obese.

Researchers found that moderately to severely obese prostate cancer patients (i.e., with a body mass index of greater than 35) do have larger prostate shifts during treatment, which can lead to radiation treatments not being delivered to the same spot every day, potentially compromising the treatment. The percentage of moderately to severely obese patients with a left to right shift of greater than 10 millimeters was 21.2 percent compared to only 1.3 percent for patients of a normal weight.

IGRT is a new type of radiation therapy that uses normal EBRT guided by imaging, such as CT scans, ultrasound or X-rays taken in the treatment room just before the patient is given radiation on a daily basis. All patients receive imaging scans as part of the planning process. However with IGRT, doctors are able to compare the earlier images with those taken before each treatment to adjust the dose if necessary.

Researchers determined that the radiation treatment modality used does impact outcomes. IGRT allows for correction of target displacements from the planned position before radiation delivery begins, so shifts may be corrected easily and thus may lead to improved control rates for obese prostate cancer patients.

“All patients deserve the treatment that is going to give them the best chance at cure and survival,” James R. Wong, M.D., lead author of the study and chair of radiation oncology at Morristown Memorial Hospital, said. “With the results of this study, we now know that obese patients have a unique complication when it comes to planning their treatment but that we can try to correct it simply by using IGRT instead of EBRT. I encourage overweight men and their families to talk to their doctors about IGRT when considering their treatment options.”


Story Source:

The above story is based on materials provided by American Society for Radiation Oncology. Note: Materials may be edited for content and length.


Cite This Page:

American Society for Radiation Oncology. "Image-guided Radiation Therapy May Improve Outcomes For Obese Prostate Cancer Patients." ScienceDaily. ScienceDaily, 3 September 2009. <www.sciencedaily.com/releases/2009/09/090902151119.htm>.
American Society for Radiation Oncology. (2009, September 3). Image-guided Radiation Therapy May Improve Outcomes For Obese Prostate Cancer Patients. ScienceDaily. Retrieved April 18, 2014 from www.sciencedaily.com/releases/2009/09/090902151119.htm
American Society for Radiation Oncology. "Image-guided Radiation Therapy May Improve Outcomes For Obese Prostate Cancer Patients." ScienceDaily. www.sciencedaily.com/releases/2009/09/090902151119.htm (accessed April 18, 2014).

Share This



More Health & Medicine News

Friday, April 18, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Scientists Create Stem Cells From Adult Skin Cells

Scientists Create Stem Cells From Adult Skin Cells

Newsy (Apr. 17, 2014) The breakthrough could mean a cure for some serious diseases and even the possibility of human cloning, but it's all still a way off. Video provided by Newsy
Powered by NewsLook.com
Obama: 8 Million Healthcare Signups

Obama: 8 Million Healthcare Signups

AP (Apr. 17, 2014) President Barack Obama gave a briefing Thursday announcing 8 million people have signed up under the Affordable Care Act. He blasted continued Republican efforts to repeal the law. (April 17) Video provided by AP
Powered by NewsLook.com
Is Apathy A Sign Of A Shrinking Brain?

Is Apathy A Sign Of A Shrinking Brain?

Newsy (Apr. 17, 2014) A recent study links apathetic feelings to a smaller brain. Researchers say the results indicate a need for apathy screening for at-risk seniors. Video provided by Newsy
Powered by NewsLook.com
Could Even Casual Marijuana Use Alter Your Brain?

Could Even Casual Marijuana Use Alter Your Brain?

Newsy (Apr. 16, 2014) A new study conducted by researchers at Northwestern and Harvard suggests even casual marijuana use can alter your brain. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins