Featured Research

from universities, journals, and other organizations

Rise In Weight-loss Drugs Prescribed To Combat Childhood Obesity

Date:
September 3, 2009
Source:
Wiley-Blackwell
Summary:
Thousands of children and adolescents are using anti-obesity drugs that in the UK are only licensed for use by adults. The number of young people receiving prescriptions for these drugs has increased 15-fold since 1999, but most stop using them before they could expect to see any benefit, according to a new study.

Thousands of children and adolescents are using anti-obesity drugs that in the UK are only licensed for use by adults. The number of young people receiving prescriptions for these drugs has increased 15-fold since 1999, but most stop using them before they could expect to see any benefit, according to a new study.

The study, published in the British Journal of Clinical Pharmacology, focuses on prescriptions in the UK, where the drugs are not licensed for use under the age of 18. Extrapolated across the whole population, the results indicate that around 1,300 young people are now being prescribed off-licence anti-obesity drugs each year.

More than three quarters of those included in the study received prescriptions for orlistat, also known as Xenical or Alli. Orlistat has been approved for children as young as 12 in the US, but only for adults in the UK. Most patients given orlistat stopped using it very quickly, on average after just three months, and therefore would have been unlikely to see any benefit.

"It's possible that the drugs are being given inappropriately, or that they have excessive side effects that make young people discontinue their use. On the other hand they could be expecting the drugs to deliver a miracle "quick fix" and stop using them when sudden, rapid weight loss does not occur," said Russell Viner, one of the authors of the study based at the General & Adolescent Paediatrics Unit at University College London.

As anti-obesity medications are expensive, not sticking to drug programmes wastes valuable resources. Study author Ian Wong says that children who are prescribed orlistat may need more support and should be made fully aware of the potential side effects, which include loose, oily stools if fat intake is not reduced.

"You have to tell them that, yes, it is healthier not to absorb the fat, but if they continue to eat as much as they used to then it will be really unpleasant. The key thing is that the drug itself is not the answer. Kids should only be using it as part of a comprehensive weight-loss programme," said Wong.

The researchers used data from the General Practice Research Database, which covers around 5% of the UK population. 452 children and adolescents were prescribed anti-obesity drugs between 1999 and 2006. Over eight years, the number of young people receiving prescriptions rose 15-fold from 0.006 per 1,000 to 0.091 per 1,000.

According to the researchers, it is highly unlikely that the drugs are doing any damage, as well-conducted short-term clinical trials did not report life-threatening side-effects in young people. But they say further research into the safety and efficacy of anti-obesity drugs in children and adolescents in clinical practice is warranted, particularly considering the dramatic increase in prescriptions and likely further increases due to childhood obesity globally.


Story Source:

The above story is based on materials provided by Wiley-Blackwell. Note: Materials may be edited for content and length.


Journal Reference:

  1. Viner, R.M., Hsia, Y., Neubert., and Wong, I.C.K. Rise in anti-obesity drug prescribing for children and adolescents in the UK: a population-based study. British Journal of Clinical Pharmacology, 2009; DOI: 10.1111/j.1365-2125.2009.03528.x

Cite This Page:

Wiley-Blackwell. "Rise In Weight-loss Drugs Prescribed To Combat Childhood Obesity." ScienceDaily. ScienceDaily, 3 September 2009. <www.sciencedaily.com/releases/2009/09/090902195238.htm>.
Wiley-Blackwell. (2009, September 3). Rise In Weight-loss Drugs Prescribed To Combat Childhood Obesity. ScienceDaily. Retrieved April 17, 2014 from www.sciencedaily.com/releases/2009/09/090902195238.htm
Wiley-Blackwell. "Rise In Weight-loss Drugs Prescribed To Combat Childhood Obesity." ScienceDaily. www.sciencedaily.com/releases/2009/09/090902195238.htm (accessed April 17, 2014).

Share This



More Health & Medicine News

Thursday, April 17, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Could Even Casual Marijuana Use Alter Your Brain?

Could Even Casual Marijuana Use Alter Your Brain?

Newsy (Apr. 16, 2014) A new study conducted by researchers at Northwestern and Harvard suggests even casual marijuana use can alter your brain. Video provided by Newsy
Powered by NewsLook.com
Thousands Of Vials Of SARS Virus Go Missing

Thousands Of Vials Of SARS Virus Go Missing

Newsy (Apr. 16, 2014) A research institute in Paris somehow misplaced more than 2,000 vials of the deadly SARS virus. Video provided by Newsy
Powered by NewsLook.com
Formerly Conjoined Twins Released From Dallas Hospital

Formerly Conjoined Twins Released From Dallas Hospital

Newsy (Apr. 16, 2014) Conjoined twins Emmett and Owen Ezell were separated by doctors in August. Now, nearly nine months later, they're being released from the hospital. Video provided by Newsy
Powered by NewsLook.com
Ebola Outbreak Now Linked To 121 Deaths

Ebola Outbreak Now Linked To 121 Deaths

Newsy (Apr. 15, 2014) The ebola virus outbreak in West Africa is now linked to 121 deaths. Health officials fear the virus will continue to spread in urban areas. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins