Featured Research

from universities, journals, and other organizations

Bioluminescence Imaging Used For Eye Cancer Detection

Date:
October 14, 2009
Source:
Association for Research in Vision and Ophthalmology
Summary:
At the moment, doctors rely on biopsy analysis to determine the progression of eye cancer. However, researchers now believe that a new technology, bioluminescence imaging, will allow doctors to detect tumors earlier and quickly choose a method of treatment that doesn't necessarily involve eye surgery.

At the moment, doctors rely on biopsy analysis to determine the progression of eye cancer. However, researchers now believe that a new technology, bioluminescence imaging (BLI), will allow doctors to detect tumors earlier and quickly choose a method of treatment that doesn't necessarily involve eye surgery.

Related Articles


BLI is a new technology that uses the making and giving off of light by an organism to map diseases in a non-invasive way. Scientists have harnessed this technology to delicately detect and monitor various diseases, including eye cancer. BLI has several advantages over biopsy analysis, including in vivo monitoring, higher sensitivity, easier use and an overall more accurate correlation between cell numbers detected and tumor growth.

A study detailed in the Association for Research in Vision and Ophthalmology's peer-reviewed Investigative Ophthalmology & Visual Science ("Non-invasive visualization of retinoblastoma growth and metastasis via bioluminescence imaging") shows how the researchers, led by Qian Huang, MD, PhD, of the First People's Hospital in Shanghai, China, were able to effectively create human eye tumors in mice using particular genes to label eye cancer.

BLI was then performed on the mice using the NightOwl LB 981 Molecular Imaging System to monitor the growth and succession of these created tumors.

"BLI allowed sensitive and quantitative localization and monitoring of intraocular and metastatic tumor growth in vivo and thus might be a useful tool to study cancer biology as well as anti-cancer therapies," said Huang.

Eye cancer is the most common and aggressive form of cancer found in children under the age of 5. As with most cancers, locating the tumors during the early stages of the disease is key. "Eye removal is usually performed for larger tumors. Small tumors are treated using therapeutic approaches such as chemotherapy. Because of the fast progression, early detection is important for preservation of vision, eye retention and even survival," says Huang.


Story Source:

The above story is based on materials provided by Association for Research in Vision and Ophthalmology. Note: Materials may be edited for content and length.


Cite This Page:

Association for Research in Vision and Ophthalmology. "Bioluminescence Imaging Used For Eye Cancer Detection." ScienceDaily. ScienceDaily, 14 October 2009. <www.sciencedaily.com/releases/2009/10/091013112516.htm>.
Association for Research in Vision and Ophthalmology. (2009, October 14). Bioluminescence Imaging Used For Eye Cancer Detection. ScienceDaily. Retrieved November 28, 2014 from www.sciencedaily.com/releases/2009/10/091013112516.htm
Association for Research in Vision and Ophthalmology. "Bioluminescence Imaging Used For Eye Cancer Detection." ScienceDaily. www.sciencedaily.com/releases/2009/10/091013112516.htm (accessed November 28, 2014).

Share This


More From ScienceDaily



More Health & Medicine News

Friday, November 28, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Ebola Leaves Orphans Alone in Sierra Leone

Ebola Leaves Orphans Alone in Sierra Leone

AFP (Nov. 27, 2014) — The Ebola epidemic sweeping Sierra Leone is having a profound effect on the country's children, many of whom have been left without any family members to support them. Duration: 01:02 Video provided by AFP
Powered by NewsLook.com
Experimental Ebola Vaccine Shows Promise In Human Trial

Experimental Ebola Vaccine Shows Promise In Human Trial

Newsy (Nov. 27, 2014) — A recent test of a prototype Ebola vaccine generated an immune response to the disease in subjects. Video provided by Newsy
Powered by NewsLook.com
Pet Dogs to Be Used in Anti-Ageing Trial

Pet Dogs to Be Used in Anti-Ageing Trial

Reuters - Innovations Video Online (Nov. 26, 2014) — Researchers in the United States are preparing to discover whether a drug commonly used in human organ transplants can extend the lifespan and health quality of pet dogs. Video provided by Reuters
Powered by NewsLook.com
Today's Prostheses Are More Capable Than Ever

Today's Prostheses Are More Capable Than Ever

Newsy (Nov. 26, 2014) — Advances in prosthetics are making replacement body parts stronger and more lifelike than they’ve ever been. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:

Strange & Offbeat Stories

 

Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins