Featured Research

from universities, journals, and other organizations

Three-day Course Of Antibiotics May Be Sufficient Following Tonsillectomy

Date:
October 20, 2009
Source:
JAMA and Archives Journals
Summary:
Children who receive a three-day course of antibiotics following tonsillectomy rather than a seven-day course appear to have no differences in pain or how quickly they return to a normal diet and activity level, according to a new report.

Children who receive a three-day course of antibiotics following tonsillectomy rather than a seven-day course appear to have no differences in pain or how quickly they return to a normal diet and activity level, according to a report in the October issue of Archives of Otolaryngology-Head & Neck Surgery, one of the JAMA/Archives journals.

About 45.6 of every 10,000 children younger than 15 undergo tonsillectomies, most often as a treatment for sleep-related breathing disorders and recurrent tonsillitis, according to background information in the article. Tonsillectomy is a relatively safe procedure with a low death rate, but complications such as pain, bleeding, lethargy and bad breath often occur, particularly in the week following surgery.

"Pain can lead to decreased oral intake and ultimately dehydration," the authors write. "The use of postoperative antibiotics to relieve pain following pediatric tonsillectomy was first reported more than 50 years ago. It is thought that the normal oral bacterial flora colonize the denuded tonsilar fossae [cavity] and release inflammatory mediators that cause pain. Antibiotic use after tonsillectomy may quantitatively lessen the bacterial content and thus reduce pain."

Paul E. Johnson, M.D., of New York-Presbyterian Hospital/Weill Cornell Medical Center, New York, and colleagues studied 49 patients scheduled to undergo tonsillectomy with or without adenoidectomy (removal of glands in the back of the throat). Twenty-six of the patients were randomly assigned to receive seven days of postoperative antibiotics, and 23 received three days of antibiotics followed by four days of placebo. Parents were asked to record how much pain medication the child took for the first seven days after surgery, as well as when the child resumed a normal diet and activity level and whether he or she required treatment for bleeding or dehydration.

A total of 47 patients (96 percent) completed the study. No statistically significant difference was observed between the two groups in postoperative pain or in the amount of time it took children to resume their normal diet and activity level.

One adverse effect from the antibiotics -- diarrhea -- was reported in one patient in each study group. "A potential disadvantage [of a shorter course of antibiotics], outside of the study measures, would be increased postoperative fever and infection," the authors write. Both patients with this problem, and one patient with postoperative bleeding, were in the seven-day antibiotic group.

"Based on our results, a three-day course of antibiotics is as effective as a seven-day course," the authors write. "A shorter course of antibiotics carries other potential advantages, including decreased cost, increased patient compliance with medications and a decrease in antibiotic-associated complications and bacterial resistance."


Story Source:

The above story is based on materials provided by JAMA and Archives Journals. Note: Materials may be edited for content and length.


Journal Reference:

  1. Paul E. Johnson; Scott M. Rickert; Jacqueline Jones. Duration-Related Efficacy of Postoperative Antibiotics Following Pediatric Tonsillectomy: A Prospective, Randomized, Placebo-Controlled Trial. Archives of Otolaryngology - Head and Neck Surgery, 2009; 135 (10): 984 DOI: 10.1001/archoto.2009.146

Cite This Page:

JAMA and Archives Journals. "Three-day Course Of Antibiotics May Be Sufficient Following Tonsillectomy." ScienceDaily. ScienceDaily, 20 October 2009. <www.sciencedaily.com/releases/2009/10/091019172335.htm>.
JAMA and Archives Journals. (2009, October 20). Three-day Course Of Antibiotics May Be Sufficient Following Tonsillectomy. ScienceDaily. Retrieved September 21, 2014 from www.sciencedaily.com/releases/2009/10/091019172335.htm
JAMA and Archives Journals. "Three-day Course Of Antibiotics May Be Sufficient Following Tonsillectomy." ScienceDaily. www.sciencedaily.com/releases/2009/10/091019172335.htm (accessed September 21, 2014).

Share This



More Health & Medicine News

Sunday, September 21, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Sierra Leone in Lockdown to Control Ebola

Sierra Leone in Lockdown to Control Ebola

AP (Sep. 21, 2014) Sierra Leone residents remained in lockdown on Saturday as part of a massive effort to confine millions of people to their homes in a bid to stem the biggest Ebola outbreak in history. (Sept. 20) Video provided by AP
Powered by NewsLook.com
Sierra Leone's Nationwide Ebola Curfew Underway

Sierra Leone's Nationwide Ebola Curfew Underway

Newsy (Sep. 20, 2014) Sierra Leone is locked down as aid workers and volunteers look for new cases of Ebola. Video provided by Newsy
Powered by NewsLook.com
Changes Found In Brain After One Dose Of Antidepressants

Changes Found In Brain After One Dose Of Antidepressants

Newsy (Sep. 19, 2014) A study suggest antidepressants can kick in much sooner than previously thought. Video provided by Newsy
Powered by NewsLook.com
Could Grief Affect The Immune Systems Of Senior Citizens?

Could Grief Affect The Immune Systems Of Senior Citizens?

Newsy (Sep. 19, 2014) The study found elderly people are much more likely to become susceptible to infection than younger adults going though a similar situation. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins