Featured Research

from universities, journals, and other organizations

Elevated biomarkers lead to diminished quality of life in heart attack patients post-discharge

Date:
November 15, 2009
Source:
Henry Ford Health System
Summary:
Many heart attack patients have high levels of cardiac biomarkers in the blood for several months after leaving the hospital, with more shortness of breath and chest pain, according to new study.

Many heart attack patients have high levels of cardiac biomarkers in the blood for several months after leaving the hospital, with more shortness of breath and chest pain, according to a Henry Ford Hospital study.

The study examined a subset of patients in a 4,500-patient heart attack registry from 24 24 U.S. hospitals and found:

  • 9 percent had elevated levels of the biomarker troponin (TnT) after six months.
  • 33 percent had elevated level of the biomarker N-terminal pro-B-type Natriuretic Peptide (NTBNP) after six months.

Both TnT and NTBNP are associated with shortness of breath; NTBNP is associated with angina. A biomarker is a protein measured in the blood whose concentration can indicate the presence or severity of disease.

The study is being presented at the American Heart Association's annual scientific conference Nov. 14-18 in Orlando.

"These elevated biomarkers are definitely associated with a reduced quality of life for patients and may signal even worse outcomes," says David Lanfear, M.D., a heart failure physician at Henry Ford and lead author of the study.

"This data raises two important issues. The first is whether the biomarkers are a sign of ongoing problems or a reflection of the past heart attack itself. The second is whether closer monitoring of patients post heart attack can help target our treatment to those who need it most."

For the study, researchers assessed the biomarker levels in patients one month and six months following their discharge from the hospital. At one and six months, 14 percent and 9 percent of patients had elevated levels of TnT; at one and six months, 55 percent and 33 percent of patients had elevated levels of NTBNP.

The study was funded by the National Institutes of Health's National Heart, Lung and Blood Institute (P50HL077113).


Story Source:

The above story is based on materials provided by Henry Ford Health System. Note: Materials may be edited for content and length.


Cite This Page:

Henry Ford Health System. "Elevated biomarkers lead to diminished quality of life in heart attack patients post-discharge." ScienceDaily. ScienceDaily, 15 November 2009. <www.sciencedaily.com/releases/2009/11/091115191017.htm>.
Henry Ford Health System. (2009, November 15). Elevated biomarkers lead to diminished quality of life in heart attack patients post-discharge. ScienceDaily. Retrieved September 20, 2014 from www.sciencedaily.com/releases/2009/11/091115191017.htm
Henry Ford Health System. "Elevated biomarkers lead to diminished quality of life in heart attack patients post-discharge." ScienceDaily. www.sciencedaily.com/releases/2009/11/091115191017.htm (accessed September 20, 2014).

Share This



More Health & Medicine News

Saturday, September 20, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Sierra Leone's Nationwide Ebola Curfew Underway

Sierra Leone's Nationwide Ebola Curfew Underway

Newsy (Sep. 20, 2014) Sierra Leone is locked down as aid workers and volunteers look for new cases of Ebola. Video provided by Newsy
Powered by NewsLook.com
Changes Found In Brain After One Dose Of Antidepressants

Changes Found In Brain After One Dose Of Antidepressants

Newsy (Sep. 19, 2014) A study suggest antidepressants can kick in much sooner than previously thought. Video provided by Newsy
Powered by NewsLook.com
Could Grief Affect The Immune Systems Of Senior Citizens?

Could Grief Affect The Immune Systems Of Senior Citizens?

Newsy (Sep. 19, 2014) The study found elderly people are much more likely to become susceptible to infection than younger adults going though a similar situation. Video provided by Newsy
Powered by NewsLook.com
Jury Delivers Verdict in Salmonella Trial

Jury Delivers Verdict in Salmonella Trial

AP (Sep. 19, 2014) A federal jury has convicted three people in connection with an outbreak of salmonella poisoning five years ago that sickened hundreds of people and was linked to a number of deaths. (Sept. 19) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins