Featured Research

from universities, journals, and other organizations

Risk of blood clot after surgery higher and lasts longer than previously thought

Date:
December 5, 2009
Source:
BMJ-British Medical Journal
Summary:
The risk of having a potentially fatal blood clot after surgery is higher and lasts for longer than had previously been thought, concludes new research.

The risk of having a potentially fatal blood clot after surgery is higher and lasts for longer than had previously been thought, concludes new research published on the British Medical Journal website.

Related Articles


This has important implications as most patients receive preventive (anti-clotting) therapy only whilst in hospital, or for up to five weeks after certain high-risk operations. And those undergoing day surgery are unlikely to be considered for preventive therapy at all.

The risk of venous thromboembolism (a collective term for deep vein thrombosis and pulmonary embolism) is known to increase after surgery, particularly after major orthopaedic (joint) surgery. The risk is thought to be highest during the first few weeks after an operation but little is known about the exact pattern and scale of this increased risk.

So an international team of researchers set out to examine the pattern of increased risk of venous thromboembolism over time and after different types of surgery

Their findings are based on NHS hospital admission and death records for 947,454 middle aged UK women recruited in 1996-2001 as part of the Million Women Study. Each woman was tracked for an average of 6.2 years.

Compared to the risk without surgery, women were almost 70 times more likely to be admitted with venous thromboembolism during the first six weeks after an inpatient operation and almost 10 times more likely after a day case operation.

The risks were lower but still elevated 7-12 weeks after surgery, and in most cases the risk remained for at least one year. Risk also varied considerably by type of surgery, being highest after inpatient surgery for hip or knee replacement, cancer and fracture.

In real terms, this means that 1 in 140 middle aged women in the UK will be admitted to hospital with venous thromboembolism during the 12 weeks after any inpatient surgery, 1 in 45 after hip or knee replacement surgery, and 1 in 85 after surgery for cancer. This compares with 1 in 815 after day case procedure and only 1 in 6,200 women during a 12 week period without surgery.

These findings suggest that there is a substantially increased risk of venous thromboembolism after many different types of surgery that lasts for up to 12 weeks postoperatively, conclude the authors.

This study broadens our previous understanding of short term risk of venous thromboembolism in certain types of surgery, particularly for day case surgery, says Alexander (Ander) Cohen, a vascular physician at King's College Hospital, in an accompanying editorial.

He also suggests that the event rates derived from this study "are probably much lower than the true values, mainly because many deep vein thromboses and pulmonary embolisms are undiagnosed, untreated, and managed out of hospital."

These findings indicate that we should be investigating the rates of venous thromboembolism, the use of preventive anti-clotting therapy, and the length of therapy in a wider range of patients. They should also make us consider whether treatment should be extended for more than five weeks in any group of patients, he concludes.


Story Source:

The above story is based on materials provided by BMJ-British Medical Journal. Note: Materials may be edited for content and length.


Cite This Page:

BMJ-British Medical Journal. "Risk of blood clot after surgery higher and lasts longer than previously thought." ScienceDaily. ScienceDaily, 5 December 2009. <www.sciencedaily.com/releases/2009/12/091203222141.htm>.
BMJ-British Medical Journal. (2009, December 5). Risk of blood clot after surgery higher and lasts longer than previously thought. ScienceDaily. Retrieved October 25, 2014 from www.sciencedaily.com/releases/2009/12/091203222141.htm
BMJ-British Medical Journal. "Risk of blood clot after surgery higher and lasts longer than previously thought." ScienceDaily. www.sciencedaily.com/releases/2009/12/091203222141.htm (accessed October 25, 2014).

Share This



More Health & Medicine News

Saturday, October 25, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

IKEA Desk Converts From Standing to Sitting With One Button

IKEA Desk Converts From Standing to Sitting With One Button

Buzz60 (Oct. 24, 2014) IKEA is out with a new convertible desk that can convert from a sitting desk to a standing one with just the push of a button. Jen Markham explains. Video provided by Buzz60
Powered by NewsLook.com
Ebola Protective Suits Being Made in China

Ebola Protective Suits Being Made in China

AFP (Oct. 24, 2014) A factory in China is busy making Ebola protective suits for healthcare workers and others fighting the spread of the virus. Duration: 00:38 Video provided by AFP
Powered by NewsLook.com
WHO: Millions of Ebola Vaccine Doses by 2015

WHO: Millions of Ebola Vaccine Doses by 2015

AP (Oct. 24, 2014) The World Health Organization said on Friday that millions of doses of two experimental Ebola vaccines could be ready for use in 2015 and five more experimental vaccines would start being tested in March. (Oct. 24) Video provided by AP
Powered by NewsLook.com
Doctor in NYC Quarantined With Ebola

Doctor in NYC Quarantined With Ebola

AP (Oct. 24, 2014) An emergency room doctor who recently returned to the city after treating Ebola patients in West Africa has tested positive for the virus. He's quarantined in a hospital. (Oct. 24) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins