Featured Research

from universities, journals, and other organizations

Urine test for pediatric obstructive sleep apnea possible

Date:
December 14, 2009
Source:
American Thoracic Society
Summary:
Researchers have discovered a technique that is able to determine whether a child has obstructive sleep apnea or habitual snoring by screening their urine.

Researchers at the University of Chicago have discovered a technique that is able to determine whether a child has obstructive sleep apnea (OSA) or habitual snoring by screening their urine.

"These findings open up the possibility of developing a relatively simple urine test that could detect OSA in snoring children. This would alleviate the need for costly and inconvenient sleep studies in children who snore, only about 20 to 30 percent of whom actually have OSA," said lead author David Gozal, M.D., professor and chairman of the pediatrics department at the University of Chicago.

The study results are published in the December 15 issue of the American Thoracic Society's American Journal of Respiratory and Critical Care Medicine.

Dr. Gozal and researchers from University of Chicago and the University of Louisville studied 90 children who were referred to the sleep clinic to be evaluated for suspected sleep disordered breathing. They also recruited 30 healthy, non-snoring children from the community to serve as controls. The children all underwent standard overnight polysomnography and were categorized either as having OSA, habitual snoring or no sleep disordered breathing.

The children's first sample of urine was collected the morning after the sleep study. The researchers used a sophisticated electrophoresis technique to screen hundreds of proteins simultaneously and found that a number of the proteins were differently expressed in children with OSA compared to children with habitual snoring or healthy, non-snoring children.

"It was rather unexpected that the urine would provide us with the ability to identify OSA," said Dr. Gozal. "However, the field of biomarkers is one that is under marked expansion and this certainly opens the way for possible simple diagnostic screening methods in the future."

While it is estimated that one to three percent of all children up to the age of nine may suffer from OSA, many more (up to 12 percent) experience habitual snoring. Because OSA can lead to cognitive, behavioral, cardiovascular and metabolic consequences in children, differentiating it from habitual snoring is essential. The initial approach is surgical by removing the enlarged tonsils and adenoids, and some children may end up needing CPAP after their surgery.

"We wish to validate these findings in urine samples from many children from laboratories around the country and to develop a simple color-based test that can be done in the physician office or by the parents," said Dr. Gozal.


Story Source:

The above story is based on materials provided by American Thoracic Society. Note: Materials may be edited for content and length.


Cite This Page:

American Thoracic Society. "Urine test for pediatric obstructive sleep apnea possible." ScienceDaily. ScienceDaily, 14 December 2009. <www.sciencedaily.com/releases/2009/12/091207095505.htm>.
American Thoracic Society. (2009, December 14). Urine test for pediatric obstructive sleep apnea possible. ScienceDaily. Retrieved April 19, 2014 from www.sciencedaily.com/releases/2009/12/091207095505.htm
American Thoracic Society. "Urine test for pediatric obstructive sleep apnea possible." ScienceDaily. www.sciencedaily.com/releases/2009/12/091207095505.htm (accessed April 19, 2014).

Share This



More Health & Medicine News

Saturday, April 19, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

'Holy Grail' Of Weight Loss? New Find Could Be It

'Holy Grail' Of Weight Loss? New Find Could Be It

Newsy (Apr. 18, 2014) In a potential breakthrough for future obesity treatments, scientists have used MRI scans to pinpoint brown fat in a living adult for the first time. Video provided by Newsy
Powered by NewsLook.com
Little Progress Made In Fighting Food Poisoning, CDC Says

Little Progress Made In Fighting Food Poisoning, CDC Says

Newsy (Apr. 18, 2014) A new report shows rates of two foodborne infections increased in the U.S. in recent years, while salmonella actually dropped 9 percent. Video provided by Newsy
Powered by NewsLook.com
Scientists Create Stem Cells From Adult Skin Cells

Scientists Create Stem Cells From Adult Skin Cells

Newsy (Apr. 17, 2014) The breakthrough could mean a cure for some serious diseases and even the possibility of human cloning, but it's all still a way off. Video provided by Newsy
Powered by NewsLook.com
Obama: 8 Million Healthcare Signups

Obama: 8 Million Healthcare Signups

AP (Apr. 17, 2014) President Barack Obama gave a briefing Thursday announcing 8 million people have signed up under the Affordable Care Act. He blasted continued Republican efforts to repeal the law. (April 17) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins