Featured Research

from universities, journals, and other organizations

Genetic ancestry highly correlated with ethnic and linguistic groups in Asia

Date:
December 14, 2009
Source:
Agency for Science, Technology and Research (A*STAR), Singapore
Summary:
Several genome-wide studies of human genetic diversity have been conducted on European populations. Now, for the first time, these studies have been extended to 73 Southeast Asian (SEA) and East Asian (EA) populations. In a new paper, over 90 scientists from the Human Genome Organization's Pan-Asian SNP Consortium report that their study conducted within and between different populations in Asia continent showed that genetic ancestry was highly correlated with ethnic and linguistic groups.

Several genome-wide studies of human genetic diversity have been conducted on European populations. Now, for the first time, these studies have been extended to 73 Southeast Asian (SEA) and East Asian (EA) populations.

In a paper titled, "Mapping Human Genetic Diversity in Asia," published online Science on 10 Dec. 2009, over 90 scientists from the Human Genome Organisation's (HUGO's) Pan-Asian SNP Consortium report that their study conducted within and between the different populations in the Asia continent showed that genetic ancestry was highly correlated with ethnic and linguistic groups.

The scientists also reported a clear increase in genetic diversity from northern to southern latitudes. Their findings also suggest that there was one major inflow of human migration into Asia arising from Southeast Asia, rather than multiple inflows from both southern and northern routes as previously proposed. This indicates that Southeast Asia was the major geographic source of East Asian and North Asian populations.

According to the study, the PanAsia SNP Initiative, the most recent common ancestors of Asians arrived first in India and later, some of them migrated to Thailand, and South to the lands known today as Malaysia, Indonesia, and the Philippines. The first group of settlers must have gone very far south before they settled successfully. These included the Malay Negritos , Philippine Negritos , the East Indonesians, and early settlers of the Pacific Islands. Thereafter, one or several groups of people migrated North, mixed with previous settlers there and, finally, formed various populations we now refer to as Austronesian, Austro-Asiatic, Tai-Kadai, Hmong-Mien, and Altaic.

The researchers noted that the geographical and linguistic basis of genetic subgroups in Asia clarifies the need for genetic stratification when conducting genetic and pharmacogenomic studies in this continent, and that human genetic mapping of Asia has important implications for the study of genetics and disease and for research to understand migratory patterns in human history.

HUGO President Edison Liu, M.D., who is Executive Director of the Genome Institute of Singapore (GIS), said, "This study was a milestone not only in the science that emerged, but the consortium that was formed. Ten Asian countries came together in the spirit of solidarity to understand how we were related as a people, and we finished with a truly Asian scientific community. We overcame shortage of funds and diverse operational constraints through partnerships, good will, and cultural sensitivity.

"Our next goal is to expand this collaboration to all of Asia including Central Asia and the Polynesian Islands," said Dr. Liu, one of the corresponding authors of the paper. "We also aim to be more detailed in our genomic analysis and plan to include structural variations, as well as over a million single nucleotide polymorphisms in the next analysis."

While HUGO initiated and coordinated the research, Dr. Liu pointed out, "Affymetrix, led by Dr. Giulia C. Kennedy and based in the US, is our primary technology partner in this endeavour. We greatly appreciate their support."


Story Source:

The above story is based on materials provided by Agency for Science, Technology and Research (A*STAR), Singapore. Note: Materials may be edited for content and length.


Cite This Page:

Agency for Science, Technology and Research (A*STAR), Singapore. "Genetic ancestry highly correlated with ethnic and linguistic groups in Asia." ScienceDaily. ScienceDaily, 14 December 2009. <www.sciencedaily.com/releases/2009/12/091210153546.htm>.
Agency for Science, Technology and Research (A*STAR), Singapore. (2009, December 14). Genetic ancestry highly correlated with ethnic and linguistic groups in Asia. ScienceDaily. Retrieved October 21, 2014 from www.sciencedaily.com/releases/2009/12/091210153546.htm
Agency for Science, Technology and Research (A*STAR), Singapore. "Genetic ancestry highly correlated with ethnic and linguistic groups in Asia." ScienceDaily. www.sciencedaily.com/releases/2009/12/091210153546.htm (accessed October 21, 2014).

Share This



More Health & Medicine News

Tuesday, October 21, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

How Nigeria Beat Its Ebola Outbreak

How Nigeria Beat Its Ebola Outbreak

Newsy (Oct. 20, 2014) The World Health Organization has declared Nigeria free of Ebola. Health experts credit a bit of luck and the government's initial response. Video provided by Newsy
Powered by NewsLook.com
Another Study Suggests Viagra Is Good For The Heart

Another Study Suggests Viagra Is Good For The Heart

Newsy (Oct. 20, 2014) An ingredient in erectile-dysfunction medications such as Viagra could improve heart function. Perhaps not surprising, given Viagra's history. Video provided by Newsy
Powered by NewsLook.com
Ebola Worries End for Dozens on U.S. Watch Lists

Ebola Worries End for Dozens on U.S. Watch Lists

Reuters - US Online Video (Oct. 20, 2014) Forty-three people who had contact with Thomas Eric Duncan, the first person diagnosed with Ebola in the U.S., were cleared overnight of twice-daily monitoring after 21 days of showing no symptoms. Rough Cut (no reporter narration). Video provided by Reuters
Powered by NewsLook.com
CDC Calls for New Ebola Safety Guidelines

CDC Calls for New Ebola Safety Guidelines

AP (Oct. 20, 2014) Centers for Disease Control and Prevention Director Dr. Tom Frieden laid out new guidelines for health care workers when dealing with the deadly Ebola virus including new precautions when taking off personal protective equipment. (Oct. 20) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins