Featured Research

from universities, journals, and other organizations

Dementia linked to high blood pressure years earlier

Date:
January 13, 2010
Source:
University of Pittsburgh Schools of the Health Sciences
Summary:
High blood pressure may put women at greater risk for dementia later in life by increasing white matter abnormalities in the brain, researchers report.

High blood pressure may put women at greater risk for dementia later in life by increasing white matter abnormalities in the brain, report researchers from the University of Pittsburgh Graduate School of Public Health in a study published online in the Journal of Clinical Hypertension.

"Hypertension is very common in the U.S. and many other countries, and can lead to serious health problems," said Lewis Kuller, M.D., Dr.P.H., professor of epidemiology, University of Pittsburgh Graduate School of Public Health. "Proper control of blood pressure, which remains generally poor, may be very important to prevent dementia as women age."

The study, part of the multisite and long-term Women's Health Initiative Memory Study (WHIMS), included 1,424 women 65 or older who had their blood pressure assessed annually and underwent magnetic resonance imaging (MRI) of the brain. Researchers assessed white matter lesions, which are associated with increased risks for dementia and stroke. White matter makes up 60 percent of the brain and contains nerve fibers responsible for communication among the brain's regions.

Women who, at the start of the study, were hypertensive, meaning a blood pressure of 140/90 or higher, had significantly more white matter lesions on their MRI scans eight years later than participants with normal blood pressure. Lesions were more common in the frontal lobe, the brain's emotional control center and home to personality, than in the occipital, parietal or temporal lobes.

"Women should be encouraged to control high blood pressure when they are young or in middle-age in order to prevent serious problems later on," said Dr. Kuller. "Prevention and control of elevated blood pressure and subsequent vascular disease in the brain may represent the best current preventive therapy for dementia."

Co-authors of the study include Karen L. Margolis, M.D., Health Partners Research Foundation, Minneapolis; Sarah A. Gaussoin, M.S., and Jeff Williamson, M.D., Wake Forest University School of Medicine; Nick R. Bryan, M.D., University of Pennsylvania; Diana Kerwin, M.D., Northwestern University; Marian Limacher, M.D., University of Florida; Sylvia Wassertheil-Smoller, Ph.D., Albert Einstein College of Medicine; and Jennifer G. Robinson, M.D., M.P.H., University of Iowa.

The research was funded by grants from the National Institutes of Health's National Heart, Lung, and Blood Institute and the U.S. Department of Health and Human Services.


Story Source:

The above story is based on materials provided by University of Pittsburgh Schools of the Health Sciences. Note: Materials may be edited for content and length.


Journal Reference:

  1. Kuller et al. Relationship of Hypertension, Blood Pressure, and Blood Pressure Control With White Matter Abnormalities in the Women's Health Initiative Memory Study (WHIMS) -- MRI Trial. Journal of Clinical Hypertension, 2009; no DOI: 10.1111/j.1751-7176.2009.00234.x

Cite This Page:

University of Pittsburgh Schools of the Health Sciences. "Dementia linked to high blood pressure years earlier." ScienceDaily. ScienceDaily, 13 January 2010. <www.sciencedaily.com/releases/2010/01/100112121942.htm>.
University of Pittsburgh Schools of the Health Sciences. (2010, January 13). Dementia linked to high blood pressure years earlier. ScienceDaily. Retrieved September 21, 2014 from www.sciencedaily.com/releases/2010/01/100112121942.htm
University of Pittsburgh Schools of the Health Sciences. "Dementia linked to high blood pressure years earlier." ScienceDaily. www.sciencedaily.com/releases/2010/01/100112121942.htm (accessed September 21, 2014).

Share This



More Health & Medicine News

Sunday, September 21, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Sierra Leone's Nationwide Ebola Curfew Underway

Sierra Leone's Nationwide Ebola Curfew Underway

Newsy (Sep. 20, 2014) Sierra Leone is locked down as aid workers and volunteers look for new cases of Ebola. Video provided by Newsy
Powered by NewsLook.com
Changes Found In Brain After One Dose Of Antidepressants

Changes Found In Brain After One Dose Of Antidepressants

Newsy (Sep. 19, 2014) A study suggest antidepressants can kick in much sooner than previously thought. Video provided by Newsy
Powered by NewsLook.com
Could Grief Affect The Immune Systems Of Senior Citizens?

Could Grief Affect The Immune Systems Of Senior Citizens?

Newsy (Sep. 19, 2014) The study found elderly people are much more likely to become susceptible to infection than younger adults going though a similar situation. Video provided by Newsy
Powered by NewsLook.com
Jury Delivers Verdict in Salmonella Trial

Jury Delivers Verdict in Salmonella Trial

AP (Sep. 19, 2014) A federal jury has convicted three people in connection with an outbreak of salmonella poisoning five years ago that sickened hundreds of people and was linked to a number of deaths. (Sept. 19) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins