Featured Research

from universities, journals, and other organizations

New biomarkers for predicting the spread of colon cancer

Date:
January 18, 2010
Source:
American Chemical Society
Summary:
Scientists in China are reporting discovery of two proteins present in the blood of people with colon cancer that may serve as the potential biomarkers for accurately predicting whether the disease will spread.

Scientists in China are reporting discovery of two proteins present in the blood of people with colon cancer that may serve as the potential biomarkers for accurately predicting whether the disease will spread.

Their study is in the American Chemical Society's Journal of Proteome Research.

Maode Lai and colleagues note that in 2008, 150,000 new cases of colon cancer and over 50,000 deaths from the disease occurred in the United States alone. Surgery is the main method of treating the disease. However, half of colon cancer patients undergoing surgery develop a recurrence of the disease within 5 years due to its spread, or metastasis, to other parts of the body. The spread of colon cancer can be difficult to detect and there are currently no reliable chemical markers in the body for predicting its spread, the scientists say.

In an effort to identify useful biomarkers for tracking the spread of colon cancer, the scientists compared proteins produced by primary, or original, tumor cells to those of metastasized cells came from a single individual with colon cancer. They identified two proteins that occurred at significantly higher levels in the metastatic cells than in the primary cancer cells. The two proteins could serve as potential biomarkers in a blood test for predicting the spread of colon cancer, allowing earlier intervention and treatment, the scientists say.


Story Source:

The above story is based on materials provided by American Chemical Society. Note: Materials may be edited for content and length.


Journal Reference:

  1. Xue et al. Identification of Serum Biomarkers for Colorectal Cancer Metastasis Using a Differential Secretome Approach. Journal of Proteome Research, 2010; 9 (1): 545 DOI: 10.1021/pr9008817

Cite This Page:

American Chemical Society. "New biomarkers for predicting the spread of colon cancer." ScienceDaily. ScienceDaily, 18 January 2010. <www.sciencedaily.com/releases/2010/01/100113172258.htm>.
American Chemical Society. (2010, January 18). New biomarkers for predicting the spread of colon cancer. ScienceDaily. Retrieved October 1, 2014 from www.sciencedaily.com/releases/2010/01/100113172258.htm
American Chemical Society. "New biomarkers for predicting the spread of colon cancer." ScienceDaily. www.sciencedaily.com/releases/2010/01/100113172258.htm (accessed October 1, 2014).

Share This



More Health & Medicine News

Wednesday, October 1, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Some Positive Ebola News: Outbreak 'Contained' In Nigeria

Some Positive Ebola News: Outbreak 'Contained' In Nigeria

Newsy (Sep. 30, 2014) The CDC says a new case of Ebola has not been reported in Nigeria for more than 21 days, leading to hopes the outbreak might be nearing its end. Video provided by Newsy
Powered by NewsLook.com
UN Ebola Mission Head: Immediate Action Is Crucial

UN Ebola Mission Head: Immediate Action Is Crucial

AFP (Sep. 30, 2014) The newly appointed head of the United Nations Mission for Ebola Emergency Response (UNMEER), Anthony Banbury, outlines operations to tackle the virus. Duration: 00:39 Video provided by AFP
Powered by NewsLook.com
CDC Confirms First Case of Ebola in US

CDC Confirms First Case of Ebola in US

AP (Sep. 30, 2014) The CDC has confirmed the first diagnosed case of Ebola in the United States. The patient is being treated at a Dallas hospital after traveling earlier this month from Liberia. (Sept. 30) Video provided by AP
Powered by NewsLook.com
New Breast Cancer Drug Extends Lives In Clinical Trial

New Breast Cancer Drug Extends Lives In Clinical Trial

Newsy (Sep. 30, 2014) In a clinical trial, breast cancer patients lived an average of 15 months longer when they received new drug Perjeta along with Herceptin. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins