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Cardiologists discover 'pouch' in heart that may raise stroke risk

Date:
January 20, 2010
Source:
University of California - Irvine
Summary:
Cardiologists have found a pouchlike structure inside the heart's left atrial chamber that may be a potent source of stroke-causing blood clots.

UCI's Dr. Subramaniam Krishnan says a heart pouch may be present in 30 percent to 35 percent of individuals.
Credit: Photo by UC Irvine Health Affairs

UC Irvine cardiologists have found a pouchlike structure inside the heart's left atrial chamber that may be a potent source of stroke-causing blood clots.

About 80 percent of the 700,000-plus strokes that occur annually in the U.S. are due to blood clots blocking a brain artery. In up to a third of these cases, the clots' origin cannot be determined. Study co-author Dr. Subramaniam Krishnan said the discovery of this left atrial pouch could provide answers and inform neurologists' efforts to prevent stroke recurrences.

Krishnan and Dr. Miguel Salazar of UCI first spotted the pouch during autopsy research. Subsequent ultrasound and CT scans of patients' hearts confirmed the finding. The researchers estimate that the anatomical feature, which Krishnan likened to a kangaroo pouch, is present in 30 percent to 35 percent of individuals. Study results appear in the January issue of Journal of the American College of Cardiology: Cardiovascular Interventions.

"The cul-de-sac nature of the heart pouch can promote stagnation of the blood, forming clots that can travel into the brain and cause a stroke," Krishnan said. "It was thought that the body of the left atrium was largely smooth and unlikely to be a source of blood clots, but we have found that not to be true for roughly one in three people."

Krishnan and UCI neurologist Dr. Mark Fisher are currently studying the prevalence of the left atrial pouch in patients who have already had strokes. "This finding points to a potentially important cause of strokes," Fisher said. "The presence of this pouch could change how neurologists treat these patients and lead to new therapeutic strategies for preventing strokes."


Story Source:

The above story is based on materials provided by University of California - Irvine. Note: Materials may be edited for content and length.


Journal Reference:

  1. Subramaniam C. Krishnan, Miguel Salazar. Septal Pouch in the Left Atrium: A New Anatomical Entity With Potential for Embolic Complications. J Am Coll Cardiol Intv, 2010; 3: 98-104 DOI: 10.1016/j.jcin.2009.07.017

Cite This Page:

University of California - Irvine. "Cardiologists discover 'pouch' in heart that may raise stroke risk." ScienceDaily. ScienceDaily, 20 January 2010. <www.sciencedaily.com/releases/2010/01/100119154715.htm>.
University of California - Irvine. (2010, January 20). Cardiologists discover 'pouch' in heart that may raise stroke risk. ScienceDaily. Retrieved July 25, 2014 from www.sciencedaily.com/releases/2010/01/100119154715.htm
University of California - Irvine. "Cardiologists discover 'pouch' in heart that may raise stroke risk." ScienceDaily. www.sciencedaily.com/releases/2010/01/100119154715.htm (accessed July 25, 2014).

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