Featured Research

from universities, journals, and other organizations

Insulin research points way to better diabetes treatments

Date:
January 31, 2010
Source:
University of York
Summary:
New research significantly improves our understanding of how insulin interacts with cells in the human body with implications for the treatments of diabetes.

New research that significantly improves our understanding of how insulin interacts with cells in the human body is being published in the Proceedings of the National Academy of Sciences.

The study could have major implications for the development of treatments for Type I diabetes.

By developing and analysing a range of super active insulins, scientists from the York Structural Biology Laboratory at the University of York have been able to identify common features that point to the likely molecular structure of human insulin when it is active in the body.

The research also offers new insight into how insulin binds to insulin receptors on cells.

The research was conducted with colleagues at the Institute of Organic Chemistry and Biochemistry of the Academy of Sciences of the Czech Republic.

Dr Marek Brzozowski, from the York Structural Biology Laboratory, said: "The structures of inactive forms of insulin and the insulin receptor are reasonably well known, but documenting how they interact has proven to be a considerable scientific challenge.

"Improving our understanding of this interaction holds the key to developing far more sophisticated treatments for Type I diabetes and this research represents an important step forward."

The research could help the development of insulin treatments that can be more carefully controlled or that could be delivered without the need for injections.


Story Source:

The above story is based on materials provided by University of York. Note: Materials may be edited for content and length.


Journal Reference:

  1. Implications for the active form of human insulin based on the structural convergence of highly active hormone analogues. Proceedings of the National Academy of Sciences, 2010 (in press)

Cite This Page:

University of York. "Insulin research points way to better diabetes treatments." ScienceDaily. ScienceDaily, 31 January 2010. <www.sciencedaily.com/releases/2010/01/100125173246.htm>.
University of York. (2010, January 31). Insulin research points way to better diabetes treatments. ScienceDaily. Retrieved September 18, 2014 from www.sciencedaily.com/releases/2010/01/100125173246.htm
University of York. "Insulin research points way to better diabetes treatments." ScienceDaily. www.sciencedaily.com/releases/2010/01/100125173246.htm (accessed September 18, 2014).

Share This



More Health & Medicine News

Thursday, September 18, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

The Cost of Ebola

The Cost of Ebola

Reuters - Business Video Online (Sep. 18, 2014) As Sierra Leone prepares for a three-day "lockdown" in its latest bid to stem the spread of Ebola, Ciara Lee looks at the financial implications of fighting the largest ever outbreak of the disease. Video provided by Reuters
Powered by NewsLook.com
What HealthKit Bug Means For Your iOS Fitness Apps

What HealthKit Bug Means For Your iOS Fitness Apps

Newsy (Sep. 18, 2014) Apple has delayed the launch of the HealthKit app platform, citing a bug. Video provided by Newsy
Powered by NewsLook.com
Residents Vaccinated as Haiti Fights Cholera Epidemic

Residents Vaccinated as Haiti Fights Cholera Epidemic

AFP (Sep. 18, 2014) Haitians receive the second dose of the vaccine against cholera as part of the UN's vaccination campaign. Duration: 00:34 Video provided by AFP
Powered by NewsLook.com
Artificial Sweetener Could Promote Diabetes

Artificial Sweetener Could Promote Diabetes

Newsy (Sep. 17, 2014) Doctors once thought artificial sweeteners lacked the health risks of sugar, but a new study says they can impact blood sugar levels the same way. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins