Featured Research

from universities, journals, and other organizations

Antibodies attack immune proteins

Date:
February 1, 2010
Source:
Rockefeller University Press
Summary:
Two new studies reveal that patients with a rare autoimmune disease produce antibodies that attack microbe-fighting immune proteins called cytokines. These findings may help explain why these patients suffer recurrent yeast infections.

Two studies published online on February 1 in the Journal of Experimental Medicine reveal that patients with a rare autoimmune disease produce antibodies that attack microbe-fighting immune proteins called cytokines. These findings may help explain why these patients suffer recurrent yeast infections.

Related Articles


Autoimmune polyendocrine syndrome, or APS-I, afflicts one in 100,000 people and is characterized by disrupted thyroid and adrenal gland function and recurrent skin infections with one type of yeast. Normally, the immune system produces cytokines that help protect the body against airborne yeast and other environmental pathogens.

Two teams of researchers -- one led by Anthony Meager at the National Institute for Biological Standards and Control (UK), and the other led by Desa Lilic at Newcastle University (UK) and Jean-Laurent Casanova at Rockefeller University (New York) -- found that patients with APS-I produce autoantibodies that bind to and disarm these yeast-fighting cytokines.

It is not yet clear why these patients are prone to infection with only one type of yeast. But these studies suggest that cytokine replacement therapy might be considered in the treatment of APS-I patients.

Kisand, K., et al. 2010. J. Exp. Med. doi:10.1084/jem.20091669.

Puel, A., et al. 2010. J. Exp. Med. doi:10.1084/jem.20091983.


Story Source:

The above story is based on materials provided by Rockefeller University Press. Note: Materials may be edited for content and length.


Cite This Page:

Rockefeller University Press. "Antibodies attack immune proteins." ScienceDaily. ScienceDaily, 1 February 2010. <www.sciencedaily.com/releases/2010/02/100201093033.htm>.
Rockefeller University Press. (2010, February 1). Antibodies attack immune proteins. ScienceDaily. Retrieved November 28, 2014 from www.sciencedaily.com/releases/2010/02/100201093033.htm
Rockefeller University Press. "Antibodies attack immune proteins." ScienceDaily. www.sciencedaily.com/releases/2010/02/100201093033.htm (accessed November 28, 2014).

Share This


More From ScienceDaily



More Health & Medicine News

Friday, November 28, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Ebola Leaves Orphans Alone in Sierra Leone

Ebola Leaves Orphans Alone in Sierra Leone

AFP (Nov. 27, 2014) — The Ebola epidemic sweeping Sierra Leone is having a profound effect on the country's children, many of whom have been left without any family members to support them. Duration: 01:02 Video provided by AFP
Powered by NewsLook.com
Experimental Ebola Vaccine Shows Promise In Human Trial

Experimental Ebola Vaccine Shows Promise In Human Trial

Newsy (Nov. 27, 2014) — A recent test of a prototype Ebola vaccine generated an immune response to the disease in subjects. Video provided by Newsy
Powered by NewsLook.com
Pet Dogs to Be Used in Anti-Ageing Trial

Pet Dogs to Be Used in Anti-Ageing Trial

Reuters - Innovations Video Online (Nov. 26, 2014) — Researchers in the United States are preparing to discover whether a drug commonly used in human organ transplants can extend the lifespan and health quality of pet dogs. Video provided by Reuters
Powered by NewsLook.com
Today's Prostheses Are More Capable Than Ever

Today's Prostheses Are More Capable Than Ever

Newsy (Nov. 26, 2014) — Advances in prosthetics are making replacement body parts stronger and more lifelike than they’ve ever been. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:

Strange & Offbeat Stories

 

Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins