Featured Research

from universities, journals, and other organizations

'Milk drops' under the tongue appear to treat milk allergies

Date:
March 1, 2010
Source:
Johns Hopkins Medical Institutions
Summary:
Placing small amounts of milk protein under the tongues of children who are allergic to milk can help them overcome their allergies, according to the findings of a small study.

Placing small amounts of milk protein under the tongues of children who are allergic to milk can help them overcome their allergies, according to the findings of a small study at Johns Hopkins Children's Center and Duke University.

Related Articles


The findings were presented Feb. 28 at the annual meeting of the American Academy of Allergy, Asthma & Immunology .

The approach, known as SLIT (sublingual immune therapy), involves giving children small but increasingly higher doses of the food they are allergic to until their immune systems "learn" to tolerate the food without triggering an allergic reaction or triggering only mild symptoms. Previous research from Hopkins Children's showed that a similar approach known as oral immunotherapy can successfully treat children with milk allergies. Unlike SLIT, oral immunotherapy involves consuming milk protein rather than merely placing it under the tongue.

The current study suggests that both approaches could be effective in treating milk allergies in most patients, authors say, but that oral immunotherapy appears to be slightly more effective than SLIT. The investigators caution that the results are preliminary and that the two approaches must be compared in larger groups before their equal efficacy can be confirmed.

While both approaches work by exposing the patient to progressively higher doses of the allergenic food, SLIT is done with lower doses -- and therefore with lower risk for a severe allergic reaction. Researchers caution that both therapies can lead to violent allergic reactions in some patients, and should be always done under a doctor's supervision.

"We are very excited to see that both approaches can achieve significant improvement in children with milk allergies, but we continue to see slightly better tolerance in children on oral immunotherapy," says lead investigator Robert Wood, M.D., director of Allergy & Immunology at Hopkins Children's. "Nonetheless, SLIT emerges as a new, if slightly less powerful, weapon in our arsenal."

In the study, all 30 children ages 6 to 17 were treated with milk drops under the tongue (SLIT) for several weeks until they built up their tolerance. Once minimum tolerance was achieved, the children were divided into two groups. Ten children continued their SLIT treatment while the other 20 consumed milk powder by mouth (OIT). After three months of treatment with increasingly higher doses of milk protein, all children underwent a food challenge, which involved drinking milk under a doctor's supervision.

All children in the "by mouth" group were able to drink on average seven times more milk without an allergic reaction or with mild symptoms compared to their baseline milk challenge before the treatment. Nine of the 10 children treated with milk drops under the tongue, were able to do so.

Children in both groups experienced allergic symptoms equally often during the treatment. In the "under the tongue" group, 33 percent of the 3,619 doses of milk administered caused symptoms, compared to 35 percent of the 3,773 doses in the "by mouth" group. Most symptoms were mild, with the most common ones being mouth and throat itching and irritation. Abdominal and respiratory symptoms occurred very infrequently, the researchers report.


Story Source:

The above story is based on materials provided by Johns Hopkins Medical Institutions. Note: Materials may be edited for content and length.


Cite This Page:

Johns Hopkins Medical Institutions. "'Milk drops' under the tongue appear to treat milk allergies." ScienceDaily. ScienceDaily, 1 March 2010. <www.sciencedaily.com/releases/2010/02/100228203213.htm>.
Johns Hopkins Medical Institutions. (2010, March 1). 'Milk drops' under the tongue appear to treat milk allergies. ScienceDaily. Retrieved February 27, 2015 from www.sciencedaily.com/releases/2010/02/100228203213.htm
Johns Hopkins Medical Institutions. "'Milk drops' under the tongue appear to treat milk allergies." ScienceDaily. www.sciencedaily.com/releases/2010/02/100228203213.htm (accessed February 27, 2015).

Share This


More From ScienceDaily



More Health & Medicine News

Friday, February 27, 2015

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Sleeping Too Much Or Too Little Might Increase Stroke Risk

Sleeping Too Much Or Too Little Might Increase Stroke Risk

Newsy (Feb. 26, 2015) People who sleep more than eight hours per night are 45 percent more likely to have a stroke, according to a University of Cambridge study. Video provided by Newsy
Powered by NewsLook.com
London Show Dissects History of Forensic Science

London Show Dissects History of Forensic Science

AFP (Feb. 25, 2015) Forensic science, which has fascinated generations with its unravelling of gruesome crime mysteries, is being put under the microscope in an exhibition of real criminal investigations in London. Duration: 00:53 Video provided by AFP
Powered by NewsLook.com
Michigan Couple Celebrates Identical Triplets

Michigan Couple Celebrates Identical Triplets

AP (Feb. 25, 2015) A suburban Detroit couple who have two older children are adjusting to life after becoming parents to identical triplets _ a multiple birth a doctor calls rare. (Feb. 25) Video provided by AP
Powered by NewsLook.com
Mayor Says District of Columbia to Go Ahead With Pot Legalization

Mayor Says District of Columbia to Go Ahead With Pot Legalization

Reuters - News Video Online (Feb. 25, 2015) Washington&apos;s mayor says the District of Columbia will move forward with marijuana legalization, despite pushback from Congress. Rough Cut (no reporter narration). Video provided by Reuters
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins