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Inappropriate uses of frozen plasma, experts argue

Date:
April 6, 2010
Source:
Canadian Medical Association Journal
Summary:
Large amounts of frozen plasma are being used inappropriately, according to two Canadian medical experts.
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Large amounts of frozen plasma are being used inappropriately, states a commentary in CMAJ (Canadian Medical Association Journal).

There has been increased attention given to the clinical use of red blood cells and platelets but not enough has been paid to the use of frozen plasma.

"Two recent studies in Canada found that 45% and 48% of audited frozen plasma transfusions represented inappropriate use, according to published guidelines," write Dr. Peter Pinkerton, Department of Clinical Pathology, Sunnybrook Health Sciences Centre, and coauthor. "The most common inappropriate use was in patients for whom there was no bleeding and laboratory coagulation test results were abnormal."

A list of appropriate and inappropriate reasons for the use of frozen plasma has been compiled from critical reviews and various published guidelines.

The authors conclude that measures should be introduced to improve practice, including promoting the use of available alternatives and prospective screening of orders for transfusion of frozen plasma against practice guidelines. Also, large retrospective audits could identify hospitals in particular need of assistance in improving practice.


Story Source:

The above post is reprinted from materials provided by Canadian Medical Association Journal. Note: Materials may be edited for content and length.


Journal Reference:

  1. Pinkerton, Peter H, Callum, Jeannie L. Rationalizing the clinical use of frozen plasma. CMAJ, 2010; 0: cmaj.081933 [link]

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Canadian Medical Association Journal. "Inappropriate uses of frozen plasma, experts argue." ScienceDaily. ScienceDaily, 6 April 2010. <www.sciencedaily.com/releases/2010/03/100315125547.htm>.
Canadian Medical Association Journal. (2010, April 6). Inappropriate uses of frozen plasma, experts argue. ScienceDaily. Retrieved July 29, 2015 from www.sciencedaily.com/releases/2010/03/100315125547.htm
Canadian Medical Association Journal. "Inappropriate uses of frozen plasma, experts argue." ScienceDaily. www.sciencedaily.com/releases/2010/03/100315125547.htm (accessed July 29, 2015).

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