Featured Research

from universities, journals, and other organizations

Hair dye and smoking linked to progressive liver disease

Date:
March 24, 2010
Source:
BMJ-British Medical Journal
Summary:
Hair dye and smoking both increase the risk of progressive liver disease, suggests new research. Primary biliary cirrhosis, which is an early form of liver cirrhosis, is a long term progressive autoimmune disease, in which environmental factors are thought to play a part.

Hair dye and smoking both increase the risk of progressive liver disease, suggests research involving around 5000 people published in the journal Gut.

Primary biliary cirrhosis (PBC), which is an early form of liver cirrhosis, is a long term progressive autoimmune disease, in which environmental factors are thought to play a part.

It causes the liver's plumbing system of bile ducts to become inflamed, scarred, and blocked, leading to extensive tissue damage and irreversible, and ultimately fatal, liver cirrhosis.

The authors base their findings on two series of patients, one of which included 318 out of 381 new cases of PBC arising between 1997 and 2003 in the North East of England. The other series included 2258 out of 3217 members of the United Kingdom PBC Foundation, a national support group for people with the condition.

Finally, 2438 out of 3933 people randomly selected from the electoral roll, and matched for age and sex, were used as a comparison group.

All three groups were sent detailed questionnaires on potential environmental and genetic risk factors associated with PBC.

As expected, autoimmune diseases, such as rheumatoid arthritis, thyroid and coeliac diseases were all more common among those with PBC. And those with a family history of autoimmune disease were more likely to have PBC.

The skin condition psoriasis, urinary infections, and shingles also significantly increased the likelihood of a PBC diagnosis.

Compared to those selected from the electoral roll, both series of patients were 63% more likely to have smoked at some point in their lives, and to have started smoking before their diagnosis.

But patients with PBC were less likely to drink alcohol regularly, although this finding was not statistically significant. Previous research has indicated that alcohol is very unlikely to be a causative factor in PBC.

Less than 1% of male respondents used hair dye, whereas half of all the women surveyed did. When this was investigated among women only, those in the PBC support group were 37% more likely to develop PBC than women in the comparison group.

Respondents were not asked how often they dyed their hair, and it is not clear which component of hair dye might be responsible for this finding, say the authors.

But previous research has indicated an association between PBC and chemicals found in cosmetics, particularly octynoic acid, which is used in hair dye and nail polish, they add.


Story Source:

The above story is based on materials provided by BMJ-British Medical Journal. Note: Materials may be edited for content and length.


Journal Reference:

  1. M I Prince, S J Ducker, O F W James. Case%u2013control studies of risk factors for primary biliary cirrhosis in two United Kingdom populations. Gut, 2010; 59: 508-512 DOI: 10.1136/gut.2009.184218

Cite This Page:

BMJ-British Medical Journal. "Hair dye and smoking linked to progressive liver disease." ScienceDaily. ScienceDaily, 24 March 2010. <www.sciencedaily.com/releases/2010/03/100323212148.htm>.
BMJ-British Medical Journal. (2010, March 24). Hair dye and smoking linked to progressive liver disease. ScienceDaily. Retrieved September 16, 2014 from www.sciencedaily.com/releases/2010/03/100323212148.htm
BMJ-British Medical Journal. "Hair dye and smoking linked to progressive liver disease." ScienceDaily. www.sciencedaily.com/releases/2010/03/100323212148.htm (accessed September 16, 2014).

Share This



More Health & Medicine News

Tuesday, September 16, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

President To Send 3,000 Military Personnel To Fight Ebola

President To Send 3,000 Military Personnel To Fight Ebola

Newsy (Sep. 16, 2014) President Obama is expected to send 3,000 troops to West Africa as part of the effort to contain Ebola's spread. Video provided by Newsy
Powered by NewsLook.com
Man Floats for 31 Hours in Gulf Waters

Man Floats for 31 Hours in Gulf Waters

AP (Sep. 16, 2014) A Texas man is lucky to be alive after he and three others floated for more than a day in the Gulf of Mexico when their boat sank during a fishing trip. (Sept. 16) Video provided by AP
Powered by NewsLook.com
EU Ministers and Experts Meet to Discuss Ebola Reponse

EU Ministers and Experts Meet to Discuss Ebola Reponse

AFP (Sep. 15, 2014) The European Commission met on Monday to coordinate aid that the EU can offer to African countries affected by the Ebola outbreak. Duration: 00:58 Video provided by AFP
Powered by NewsLook.com
Despite The Risks, Antibiotics Still Overprescribed For Kids

Despite The Risks, Antibiotics Still Overprescribed For Kids

Newsy (Sep. 15, 2014) A new study finds children are prescribed antibiotics twice as often as is necessary. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins