Featured Research

from universities, journals, and other organizations

Protein linked to problems with executive thinking skills

Date:
March 30, 2010
Source:
American Academy of Neurology
Summary:
New research shows that a high level of C-reactive protein (CRP), a marker for inflammation in the blood, is associated with brain changes that are linked to problems with executive thinking skills.

New research shows that a high level of C-reactive protein (CRP), a marker for inflammation in the blood, is associated with brain changes that are linked to problems with executive thinking skills. The study is published in the March 30, 2010, issue of Neurology®, the medical journal of the American Academy of Neurology.

Related Articles


For the study, scientists examined 447 stroke and dementia-free people with an average age of 63.

Participants underwent MRI brain scans such as diffusion tensor imaging (DTI), a technique that measures water molecule movements in the brain. They also completed tests that measured verbal memory, word fluency and executive function, the process in the brain that allows for planning, decision making and selection of appropriate behavior.

The study found that higher levels of CRP led to worse performance in executive function. Higher levels of the protein also affected the frontal lobe of the brain, where some motor functions take place. Motor skills, however, were not measured in the study. Other areas of cognition, such as memory and language skills, showed no association with CRP.

Overall, the average time to complete a test of executive function was 85 seconds. Those with the highest levels of CRP took an average of seven seconds longer to complete the test than those with the lowest levels of the protein. The brain changes measured with DTI were equivalent to 12 years of aging for those with the highest levels of CRP compared to those with the lowest levels.

"The use of aspirin and statin drugs as well as physical activity and controlling weight can help lower CRP levels in the body, but our analyses did not consider whether therapy would be effective or not," said study author Heike Wersching, MD, with the University of Münster in Germany.

The study was supported by the German Research Foundation (DFG), the Volkswagen Foundation, the Marie Curie Research and Training Network-funded by the European Commission, the BMBF-Competence Network Mednet Atrial Fibrillation, BMBF-Research Consortium and the Neuromedical Foundation Münster.


Story Source:

The above story is based on materials provided by American Academy of Neurology. Note: Materials may be edited for content and length.


Cite This Page:

American Academy of Neurology. "Protein linked to problems with executive thinking skills." ScienceDaily. ScienceDaily, 30 March 2010. <www.sciencedaily.com/releases/2010/03/100329162926.htm>.
American Academy of Neurology. (2010, March 30). Protein linked to problems with executive thinking skills. ScienceDaily. Retrieved March 4, 2015 from www.sciencedaily.com/releases/2010/03/100329162926.htm
American Academy of Neurology. "Protein linked to problems with executive thinking skills." ScienceDaily. www.sciencedaily.com/releases/2010/03/100329162926.htm (accessed March 4, 2015).

Share This


More From ScienceDaily



More Mind & Brain News

Wednesday, March 4, 2015

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Former NFL Players Donate Brains to Science

Former NFL Players Donate Brains to Science

Reuters - US Online Video (Mar. 3, 2015) — Super Bowl champions Sidney Rice and Steve Weatherford donate their brains, post-mortem, to scientific research into repetitive brain trauma. Jillian Kitchener reports. Video provided by Reuters
Powered by NewsLook.com
Alzheimer's Protein Plaque Found In 20-Year-Olds

Alzheimer's Protein Plaque Found In 20-Year-Olds

Newsy (Mar. 3, 2015) — Researchers found an abnormal protein associated with Alzheimer&apos;s disease in the brains of 20-year-olds. Video provided by Newsy
Powered by NewsLook.com
This Nasal Treatment Could Help Ease Migraine Pain

This Nasal Treatment Could Help Ease Migraine Pain

Newsy (Mar. 2, 2015) — Researchers gave lidocaine to 112 patients, and about 88 percent of the subjects said they needed less migraine-relief medicine the next day. Video provided by Newsy
Powered by NewsLook.com
How Facebook Use Can Lead To Depression

How Facebook Use Can Lead To Depression

Newsy (Mar. 1, 2015) — Margaret Duffy of the University of Missouri talks about her study on the social network and the envy and depression that Facebook use can cause. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:

Strange & Offbeat Stories

 

Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins