Featured Research

from universities, journals, and other organizations

Protein linked to problems with executive thinking skills

Date:
March 30, 2010
Source:
American Academy of Neurology
Summary:
New research shows that a high level of C-reactive protein (CRP), a marker for inflammation in the blood, is associated with brain changes that are linked to problems with executive thinking skills.

New research shows that a high level of C-reactive protein (CRP), a marker for inflammation in the blood, is associated with brain changes that are linked to problems with executive thinking skills. The study is published in the March 30, 2010, issue of Neurology®, the medical journal of the American Academy of Neurology.

Related Articles


For the study, scientists examined 447 stroke and dementia-free people with an average age of 63.

Participants underwent MRI brain scans such as diffusion tensor imaging (DTI), a technique that measures water molecule movements in the brain. They also completed tests that measured verbal memory, word fluency and executive function, the process in the brain that allows for planning, decision making and selection of appropriate behavior.

The study found that higher levels of CRP led to worse performance in executive function. Higher levels of the protein also affected the frontal lobe of the brain, where some motor functions take place. Motor skills, however, were not measured in the study. Other areas of cognition, such as memory and language skills, showed no association with CRP.

Overall, the average time to complete a test of executive function was 85 seconds. Those with the highest levels of CRP took an average of seven seconds longer to complete the test than those with the lowest levels of the protein. The brain changes measured with DTI were equivalent to 12 years of aging for those with the highest levels of CRP compared to those with the lowest levels.

"The use of aspirin and statin drugs as well as physical activity and controlling weight can help lower CRP levels in the body, but our analyses did not consider whether therapy would be effective or not," said study author Heike Wersching, MD, with the University of Münster in Germany.

The study was supported by the German Research Foundation (DFG), the Volkswagen Foundation, the Marie Curie Research and Training Network-funded by the European Commission, the BMBF-Competence Network Mednet Atrial Fibrillation, BMBF-Research Consortium and the Neuromedical Foundation Münster.


Story Source:

The above story is based on materials provided by American Academy of Neurology. Note: Materials may be edited for content and length.


Cite This Page:

American Academy of Neurology. "Protein linked to problems with executive thinking skills." ScienceDaily. ScienceDaily, 30 March 2010. <www.sciencedaily.com/releases/2010/03/100329162926.htm>.
American Academy of Neurology. (2010, March 30). Protein linked to problems with executive thinking skills. ScienceDaily. Retrieved November 25, 2014 from www.sciencedaily.com/releases/2010/03/100329162926.htm
American Academy of Neurology. "Protein linked to problems with executive thinking skills." ScienceDaily. www.sciencedaily.com/releases/2010/03/100329162926.htm (accessed November 25, 2014).

Share This


More From ScienceDaily



More Mind & Brain News

Tuesday, November 25, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Are Female Bosses More Likely To Be Depressed?

Are Female Bosses More Likely To Be Depressed?

Newsy (Nov. 24, 2014) — A new study links greater authority with increased depressive symptoms among women in the workplace. Video provided by Newsy
Powered by NewsLook.com
Winter Can Cause Depression — Here's How To Combat It

Winter Can Cause Depression — Here's How To Combat It

Newsy (Nov. 23, 2014) — Millions of American suffer from seasonal depression every year. It can lead to adverse health effects, but there are ways to ease symptoms. Video provided by Newsy
Powered by NewsLook.com
Could Your Genes Be The Reason You're Single?

Could Your Genes Be The Reason You're Single?

Newsy (Nov. 21, 2014) — Researchers in Beijing discovered a gene called 5-HTA1, and carriers are reportedly 20 percent more likely to be single. Video provided by Newsy
Powered by NewsLook.com
Milestone Birthdays Can Bring Existential Crisis, Study Says

Milestone Birthdays Can Bring Existential Crisis, Study Says

Newsy (Nov. 21, 2014) — Researchers find that as people approach new decades in their lives they make bigger life decisions. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:

Strange & Offbeat Stories

 

Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins