Featured Research

from universities, journals, and other organizations

Less prep needed for colonoscopy, study finds

Date:
May 2, 2010
Source:
Henry Ford Health System
Summary:
Researchers may have found a better way to prep patients for colonoscopy procedures so they no longer need to drink a gallon of prescribed fluids prior to the procedure. The study found that patients who took a pill that is FDA-approved for chronic constipation as part of the colonoscopy prep only needed to drink half of the liquid previously required to cleanse the bowels.

Researchers at Henry Ford Hospital may have found a better way to prep patients for colonoscopy procedures so they no longer need to drink a gallon of prescribed fluids prior to the procedure.

Related Articles


The study found that patients who took a pill that is FDA-approved for chronic constipation as part of the colonoscopy prep only needed to drink half of the liquid previously required to cleanse the bowels.

While the combination did not improve polyp detection during the colonoscopy, researchers say it led to improved bowel preparation quality and was better tolerated by patients than the liquid mix of polyethylene glycol (PEG) and electrolytes alone.

"Most people say they don't want to have a colonoscopy because they find the preparation intolerable," says Chetan Pai, D.O., a Henry Ford Hospital gastroenterologist and lead author of the study.

"If physicians are able to offer a better way to prep, I think this will encourage more people to get the colonoscopies that may save their lives."

He explains that approximately 90 percent of colon cancer occurs in people over age 50, but these older adults tend to have difficulty drinking a gallon of electrolytes in preparation for the colonoscopy.

Study results were presented May 2 at Digestive Diseases Week in New Orleans.

According to the National Cancer Institute, in 2009, more than 146,000 new cases of colon and rectal cancer were diagnosed and nearly 50,000 people died from the disease. However, colon cancer is one of the most preventable forms of cancer because if it is found early through a colonoscopy screening test, it can be stopped before it has spread.

The constipation drug lubiprostone -- a chloride pump activator in tablet form -- has been used anecdotally in patients unable to tolerate drinking a full gallon of PEG and electrolytes as part of the bowel cleansing preparation for colonoscopy.

To test the effectiveness of lubiprostone as part of colonoscopy prep, Henry Ford conducted a randomized, double-blind and placebo-controlled study of 126 patients.

Researchers looked at the tolerability of the combination of lubiprostone and electrolytes, as well as electrolytes alone, and whether it was possible to reduce the volume of electrolytes required for colon cleansing.

The study was funded by Sucampo Pharmaceuticals, Inc., the manufacturer of lubiprostone.


Story Source:

The above story is based on materials provided by Henry Ford Health System. Note: Materials may be edited for content and length.


Cite This Page:

Henry Ford Health System. "Less prep needed for colonoscopy, study finds." ScienceDaily. ScienceDaily, 2 May 2010. <www.sciencedaily.com/releases/2010/05/100502173505.htm>.
Henry Ford Health System. (2010, May 2). Less prep needed for colonoscopy, study finds. ScienceDaily. Retrieved October 31, 2014 from www.sciencedaily.com/releases/2010/05/100502173505.htm
Henry Ford Health System. "Less prep needed for colonoscopy, study finds." ScienceDaily. www.sciencedaily.com/releases/2010/05/100502173505.htm (accessed October 31, 2014).

Share This



More Health & Medicine News

Friday, October 31, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Melafind: Spotting Melanoma Without a Biopsy

Melafind: Spotting Melanoma Without a Biopsy

Ivanhoe (Oct. 31, 2014) The MelaFind device is a pain-free way to check suspicious moles for melanoma, without the need for a biopsy. Video provided by Ivanhoe
Powered by NewsLook.com
Battling Multiple Myeloma

Battling Multiple Myeloma

Ivanhoe (Oct. 31, 2014) The answer isn’t always found in new drugs – repurposing an ‘old’ drug that could mean better multiple myeloma treatment, and hope. Video provided by Ivanhoe
Powered by NewsLook.com
Chronic Inflammation and Prostate Cancer

Chronic Inflammation and Prostate Cancer

Ivanhoe (Oct. 31, 2014) New information that is linking chronic inflammation in the prostate and prostate cancer, which may help doctors and patients prevent cancer in the future. Video provided by Ivanhoe
Powered by NewsLook.com
Sickle Cell: Stopping Kids’ Silent Strokes

Sickle Cell: Stopping Kids’ Silent Strokes

Ivanhoe (Oct. 31, 2014) Blood transfusions are proving crucial to young sickle cell patients by helping prevent strokes, even when there is no outward sign of brain injury. Video provided by Ivanhoe
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins