Featured Research

from universities, journals, and other organizations

Chemists create DNA assembly line

Date:
May 14, 2010
Source:
New York University
Summary:
Chemists have created a DNA assembly line that has the potential to create novel materials efficiently on the nanoscale.

Chemists at New York University and China's Nanjing University have created a DNA assembly line that has the potential to create novel materials efficiently on the nanoscale.

Their work is reported in the latest issue of the journal Nature.

"An industrial assembly line includes a factory, workers, and a conveyor system," said NYU Chemistry Professor Nadrian Seeman, the study's senior author. "We have emulated each of those features using DNA components."

The assembly line relies on three DNA-based components.

The first is DNA origami, a composition that uses a few hundred short DNA strands to direct a very long DNA strand to form structures to any desired shape. These shapes are approximately 100 x 100 nanometers in area, and about 2 nm thick (a nanometer is one billionth of a meter). DNA origami serves as the assembly line's framework and also houses its track.

The second are three DNA machines, or cassettes, that serve as programmable cargo-donating devices. The cargo species the researchers used are gold nanoparticles, which measure 5 to 10 nanometers in diameter. Changing the cassette's control sequences allows the researchers to enable or prevent the donation of the cargoes to the growing construct.

The third is a DNA "walker," which is analogous to the chassis of a car being assembled. It moves along the assembly line's track, stopping at the DNA machines to collect and carry the DNA "cargo."

As the walker moves along the pathway prescribed by the origami tile track, it encounters sequentially the three DNA devices. These devices can be switched between an "on" state, allowing its cargo to be transferred to the walker, and an "off" state, in which no transfer occurs. In this way, the DNA product at the end of the assembly line may include cargo picked up from one, two, or three of the DNA machines.

"A key feature of the assembly line is the programmability of the cargo-donating DNA machines, which allows the generation of eight different products," explained Seeman.


Story Source:

The above story is based on materials provided by New York University. Note: Materials may be edited for content and length.


Journal Reference:

  1. Hongzhou Gu, Jie Chao, Shou-Jun Xiao, Nadrian C. Seeman. A proximity-based programmable DNA nanoscale assembly line. Nature, 2010; 465 (7295): 202 DOI: 10.1038/nature09026

Cite This Page:

New York University. "Chemists create DNA assembly line." ScienceDaily. ScienceDaily, 14 May 2010. <www.sciencedaily.com/releases/2010/05/100512131509.htm>.
New York University. (2010, May 14). Chemists create DNA assembly line. ScienceDaily. Retrieved September 21, 2014 from www.sciencedaily.com/releases/2010/05/100512131509.htm
New York University. "Chemists create DNA assembly line." ScienceDaily. www.sciencedaily.com/releases/2010/05/100512131509.htm (accessed September 21, 2014).

Share This



More Matter & Energy News

Sunday, September 21, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

What This MIT Sensor Could Mean For The Future Of Robotics

What This MIT Sensor Could Mean For The Future Of Robotics

Newsy (Sep. 20, 2014) MIT researchers developed a light-based sensor that gives robots 100 times the sensitivity of a human finger, allowing for "unprecedented dexterity." Video provided by Newsy
Powered by NewsLook.com
MIT BioSuit A New Take On Traditional Spacesuits

MIT BioSuit A New Take On Traditional Spacesuits

Newsy (Sep. 19, 2014) The MIT BioSuit could be an alternative to big, bulky traditional spacesuits, but the concept needs some work. Video provided by Newsy
Powered by NewsLook.com
New Music With Recycled Instruments at Colombia Fest

New Music With Recycled Instruments at Colombia Fest

AFP (Sep. 19, 2014) Jars, bottles, caps and even a pizza box, recovered from the trash, were the elements used by four musical groups at the "RSFEST2014 Sonorities Recycling Festival", in Colombian city of Cali. Duration: 00:49 Video provided by AFP
Powered by NewsLook.com
Virtual Reality Headsets Unveiled at Tokyo Game Show

Virtual Reality Headsets Unveiled at Tokyo Game Show

AFP (Sep. 18, 2014) Several companies unveiled virtual reality headsets at the Tokyo Game Show, Asia's largest digital entertainment exhibition. Duration: 00:48 Video provided by AFP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins