Featured Research

from universities, journals, and other organizations

Statins decrease risk of clot-related diseases, study finds

Date:
May 17, 2010
Source:
American Thoracic Society
Summary:
Individuals at risk for clot-related diseases may benefit from taking common cholesterol-lowering drugs known as statins, according to a new study.

Individuals at risk for clot-related diseases may benefit from taking common cholesterol-lowering drugs known as statins, according to a study conducted by researchers at the University of Connecticut.

Related Articles


The results of the study were presented at the ATS 2010 International Conference in New Orleans.

"Previous clinical studies have indicated statins may play a role in lowering the risk of these conditions, but these studies have yielded variable estimates of the effect of statin therapy," said lead author Vanjul Agarwal, M.B.B.S. "In our study, we aimed to analyze and evaluate the effect of these drugs in patients with specific conditions related to vessel blockages."

While other studies have focused on the effects of specific statin drugs, Dr. Agarwal said the current analysis sought to evaluate the effect of statins as a whole. Researchers reviewed the results of 10 studies of more than 900,000 men and women evaluating the effect of statins in preventing venous thromboembolism (VTE), clots formed in the deep veins which pose a serious risk for heart attack and stroke. Dr. Agarwal noted that the current study included all types of VTE, with a focus on deep vein thrombosis (DVT), most commonly involving clots in the lower legs, and pulmonary embolism (PE), clots that form in the primary vessels of the lungs after migrating from other areas of the body, usually the legs, pelvis or, rarely, arms. According to study results, statin use benefited patients with all types of VTE, including DVT and PE.

Both PE and DVT can be asymptomatic and therefore difficult to detect, or easy to misdiagnose. According to the Centers for Disease Control, about 200,000 to 400,000 people in the U.S. have DVT and about 100,000 to 200,000 people have a PE. Nearly one-third of individuals with a PE die as a result of the condition.

Dr. Agarwal said statins are believed to decrease the risk of VTE by reducing inflammation, one of the factors involved in clot formation. "Statins have been found to have anti-inflammatory properties. Since thrombus formation involves inflammation, statins may reduce venous thrombus formation and thus, lower the odds of developing PE/DVT," she said.

Dr. Agarwal noted future randomized, controlled trials may help determine a course of statin therapy for patients most at risk for developing VTE.

"Patients at high risk for developing PE or DVT may be prescribed statins prophylactically," she said. "In these patients, regular use of statins could significantly reduce the incidence of PE and DVT."


Story Source:

The above story is based on materials provided by American Thoracic Society. Note: Materials may be edited for content and length.


Cite This Page:

American Thoracic Society. "Statins decrease risk of clot-related diseases, study finds." ScienceDaily. ScienceDaily, 17 May 2010. <www.sciencedaily.com/releases/2010/05/100516195649.htm>.
American Thoracic Society. (2010, May 17). Statins decrease risk of clot-related diseases, study finds. ScienceDaily. Retrieved March 30, 2015 from www.sciencedaily.com/releases/2010/05/100516195649.htm
American Thoracic Society. "Statins decrease risk of clot-related diseases, study finds." ScienceDaily. www.sciencedaily.com/releases/2010/05/100516195649.htm (accessed March 30, 2015).

Share This


More From ScienceDaily



More Health & Medicine News

Monday, March 30, 2015

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

S. Leone in New Anti-Ebola Lockdown

S. Leone in New Anti-Ebola Lockdown

AFP (Mar. 28, 2015) Sierra Leone imposed a three-day nationwide lockdown Friday for the second time in six months in a bid to prevent a resurgence of the deadly Ebola virus. Duration: 01:17 Video provided by AFP
Powered by NewsLook.com
These Popular Antibiotics Can Cause Permanent Nerve Damage

These Popular Antibiotics Can Cause Permanent Nerve Damage

Newsy (Mar. 27, 2015) A popular class of antibiotic can leave patients in severe pain and even result in permanent nerve damage. Video provided by Newsy
Powered by NewsLook.com
WH Plan to Fight Antibiotic-Resistant Germs

WH Plan to Fight Antibiotic-Resistant Germs

AP (Mar. 27, 2015) The White House on Friday announced a five-year plan to fight the threat posed by antibiotic-resistant bacteria amid fears that once-treatable germs could become deadly. (March 27) Video provided by AP
Powered by NewsLook.com
House Ready to Pass Medicare Doc Bill

House Ready to Pass Medicare Doc Bill

AP (Mar. 26, 2015) In rare bipartisan harmony, congressional leaders pushed a $214 billion bill permanently blocking physician Medicare cuts toward House passage Thursday, moving lawmakers closer to resolving a problem that has plagued them for years. (March 26) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins