Featured Research

from universities, journals, and other organizations

Mystery of healthy fat people: Why some obese people go on to become diabetic while others do not

Date:
July 29, 2010
Source:
The Biochemical Society
Summary:
It is common to find obese people – even morbidly obese people – who are healthier than their condition would normally allow. Working with subjects with a body mass index of about 56, a team of researchers investigated the inflammatory and insulin signaling pathways in the patients’ visceral adipose tissue.

It is common to find obese people -- even morbidly obese people -- who are healthier than their condition would normally allow.

Working with subjects with a body mass index of about 56, a team of researchers in Spain and Cambridge investigated the inflammatory and insulin signalling pathways in the patients' visceral adipose tissue and have published their findings in the Disease Knowledge Environment of the Biochemical Journal.

Barbarroja et al. found that the 'healthy' obese lacked an inflammatory response that was found in the unhealthy, insulin-resistant, obese.

The reason, they suggest is that there are pathways common to obesity yet unrelated to insulin resistance and pathways that lead to insulin resistance for a similar degree of obesity. It is the inflammation response that effects insulin resistance, through the expression of the cytokines interleukin 1β and interleukin 16.

Professor Peter Shepherd, Chair of the Editorial Board of the Biochemical Journal, said: "This is a very interesting finding and provides important clues as to why some obese people go on to become diabetic while others do not. It will be interesting to see if similar correlations exist with other diseases associated with obesity, such as cancer and heart disease."


Story Source:

The above story is based on materials provided by The Biochemical Society. Note: Materials may be edited for content and length.


Journal Reference:

  1. Nuria Barbarroja, Rosario Lopez-Pedrera, Maria Dolores Mayas, Eduardo Garcia-Fuentes, Lourdes Garrido-Sanchez, M Macias-Gonzalez, Rajaa El Bekay, Antonio Vidal-Puig, Francisco Tinahones. The obese healthy paradox: is inflammation the answer? Biochemical Journal, 2010; DOI: 10.1042/BJ20100285

Cite This Page:

The Biochemical Society. "Mystery of healthy fat people: Why some obese people go on to become diabetic while others do not." ScienceDaily. ScienceDaily, 29 July 2010. <www.sciencedaily.com/releases/2010/07/100729075011.htm>.
The Biochemical Society. (2010, July 29). Mystery of healthy fat people: Why some obese people go on to become diabetic while others do not. ScienceDaily. Retrieved October 20, 2014 from www.sciencedaily.com/releases/2010/07/100729075011.htm
The Biochemical Society. "Mystery of healthy fat people: Why some obese people go on to become diabetic while others do not." ScienceDaily. www.sciencedaily.com/releases/2010/07/100729075011.htm (accessed October 20, 2014).

Share This



More Health & Medicine News

Monday, October 20, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

How Nigeria Beat Its Ebola Outbreak

How Nigeria Beat Its Ebola Outbreak

Newsy (Oct. 20, 2014) The World Health Organization has declared Nigeria free of Ebola. Health experts credit a bit of luck and the government's initial response. Video provided by Newsy
Powered by NewsLook.com
Another Study Suggests Viagra Is Good For The Heart

Another Study Suggests Viagra Is Good For The Heart

Newsy (Oct. 20, 2014) An ingredient in erectile-dysfunction medications such as Viagra could improve heart function. Perhaps not surprising, given Viagra's history. Video provided by Newsy
Powered by NewsLook.com
Ebola Worries End for Dozens on U.S. Watch Lists

Ebola Worries End for Dozens on U.S. Watch Lists

Reuters - US Online Video (Oct. 20, 2014) Forty-three people who had contact with Thomas Eric Duncan, the first person diagnosed with Ebola in the U.S., were cleared overnight of twice-daily monitoring after 21 days of showing no symptoms. Rough Cut (no reporter narration). Video provided by Reuters
Powered by NewsLook.com
Fauci: Ebola Protocols to Focus on Training

Fauci: Ebola Protocols to Focus on Training

AP (Oct. 20, 2014) Dr. Anthony Fauci, head of the National Institute of Allergy and Infectious Diseases, says he expects revised CDC protocols on Ebola to focus on training, observation and ensuring health care workers are more protected. (Oct. 20) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins