Featured Research

from universities, journals, and other organizations

Hair color, socioeconomic status among risk factors for recurring basal cell carcinoma

Date:
August 30, 2010
Source:
JAMA and Archives Journals
Summary:
Patients who receive a diagnosis of the skin cancer basal cell carcinoma at a younger age -- along with those who have red hair, a higher socioeconomic status and a cancerous lesion on their upper extremities -- appear to be at higher risk of developing multiple cancers and require closer follow-up, according to a new study.

Patients who receive a diagnosis of the skin cancer basal cell carcinoma at a younger age -- along with those who have red hair, a higher socioeconomic status and a cancerous lesion on their upper extremities -- appear to be at higher risk of developing multiple cancers and require closer follow-up, according to a report in the August issue of Archives of Dermatology, one of the JAMA/Archives journals.

"Basal cell carcinoma is the most common type of cancer in people with European ancestry, and its incidence continues to increase steeply," the authors write as background information in the article. "Although basal cell carcinoma therapy is relatively straightforward and basal cell carcinoma mortality rates are extremely low, the high incidence of basal cell carcinoma and the high risk of developing multiple lesions put a major burden on limited health care resources, placing basal cell carcinoma in fifth place on the list of most expensive cancers to treat in the United States."

Risk factors for the disease include older age, being male, race and genetic predisposition, which may interact with UV light exposure or other environmental hazards. To investigate the incidence of and risk factors for single vs. multiple basal cell carcinoma lesions, Ville Kiiski, M.D., and colleagues at Erasmus Medical Center, Rotterdam, the Netherlands, studied two cohorts of 10,994 Dutch adults 55 or older, one in 1990 and one in 1999. Patients with basal cell carcinoma lesions were identified from Dutch national records and potential risk factors -- including sex, age, hair color, eye color, educational level and other demographic and health characteristics -- were determined when individuals entered the study.

A total of 524 (4.8 percent) individuals in both cohorts had basal cell carcinoma, of whom 361 had single lesions and 163 (31.1 percent) had multiple lesions. Individuals who developed their first lesion after age 75 were significantly less likely to develop multiple lesions, whereas red hair and a first lesion located on the upper extremities was associated with a significantly increased risk of developing multiple lesions.

"In contrast to developing a first lesion, high educational level was significantly positively associated with developing multiple lesions," the authors write. "This finding may be explained by the probability that people with higher levels of education (which correlates strongly with socioeconomic status) have different lifestyles (e.g., more frequent exposure to UV rays for intermittent periods)." It may also be that these individuals were more likely to develop cancer in places other than the face and neck, or because they tend to live longer and thus have more time to develop lesions, the authors note.

Known risk factors for basal cell carcinoma, including having blue eyes and fair or blond hair, were not associated with the risk for additional lesions. "The observed discrepancy among risk factor profiles of developing single or multiple basal cell carcinoma lesions may suggest that once cumulative environmental-genetic interaction has surpassed a certain threshold and resulted in a lesion, the phenotypic characteristics of patients seem less important. The clinical relevance of this finding is that physicians' risk assessment efforts should differentiate between patients at risk for a first lesion and those who have a history of basal cell carcinoma."


Story Source:

The above story is based on materials provided by JAMA and Archives Journals. Note: Materials may be edited for content and length.


Journal Reference:

  1. Ville Kiiski; Esther de Vries; Sophie C. Flohil; Monique J. Bijl; Albert Hofman; Bruno H. C. Stricker; Tamar Nijsten. Risk Factors for Single and Multiple Basal Cell Carcinomas. Arch Dermatol, 2010; 146 (8): 848-855 [link]

Cite This Page:

JAMA and Archives Journals. "Hair color, socioeconomic status among risk factors for recurring basal cell carcinoma." ScienceDaily. ScienceDaily, 30 August 2010. <www.sciencedaily.com/releases/2010/08/100816162639.htm>.
JAMA and Archives Journals. (2010, August 30). Hair color, socioeconomic status among risk factors for recurring basal cell carcinoma. ScienceDaily. Retrieved September 2, 2014 from www.sciencedaily.com/releases/2010/08/100816162639.htm
JAMA and Archives Journals. "Hair color, socioeconomic status among risk factors for recurring basal cell carcinoma." ScienceDaily. www.sciencedaily.com/releases/2010/08/100816162639.htm (accessed September 2, 2014).

Share This




More Health & Medicine News

Tuesday, September 2, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Get on Your Bike! London Cycling Popularity Soars Despite Danger

Get on Your Bike! London Cycling Popularity Soars Despite Danger

AFP (Sep. 1, 2014) Wedged between buses, lorries and cars, cycling in London isn't for the faint hearted. Nevertheless the number of people choosing to bike in the British capital has doubled over the past 15 years. Duration: 02:27 Video provided by AFP
Powered by NewsLook.com
Can You Train Your Brain To Eat Healthy?

Can You Train Your Brain To Eat Healthy?

Newsy (Sep. 1, 2014) New research says if you condition yourself to eat healthy foods, eventually you'll crave them instead of junk food. Video provided by Newsy
Powered by NewsLook.com
We've Got Mites Living In Our Faces And So Do You

We've Got Mites Living In Our Faces And So Do You

Newsy (Aug. 30, 2014) A new study suggests 100 percent of adult humans (those over 18 years of age) have Demodex mites living in their faces. Video provided by Newsy
Powered by NewsLook.com
Liberia Continues Fight Against Ebola

Liberia Continues Fight Against Ebola

AFP (Aug. 30, 2014) Authorities in Liberia try to stem the spread of the Ebola epidemic by raising awareness and setting up sanitation units for people to wash their hands. Duration: 00:41 Video provided by AFP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins