Featured Research

from universities, journals, and other organizations

Why proper nutrition is so vital in fighting infection

Date:
November 8, 2010
Source:
University of Alberta Faculty of Medicine & Dentistry
Summary:
Researchers in Canada may be able to explain why proper nutrition is so vital in fighting infection. They have discovered an amino acid, called arginine, is required to let the body know that it's being attacked by an infection.

Richard Lamb and his post doctoral fellow Virginie Mieulet, in the Faculty of Medicine & Dentistry, may be able to explain why proper nutrition is so vital in fighting infection.

Related Articles


They have discovered an amino acid, called arginine, is required to let the body know that it's being attacked by an infection.

It is still early in their work but this discovery could have implications for the millions of people in third world countries that do not get enough food and consequently become ill with infection.

It may also be the mechanism involved in chronic inflammation, like arthritis because if you have too much arginine it may cause the body to be in a constant state of thinking it is being attacked.

In a healthy person, macrophages are the first cells to arrive at the site of infection. They eat the infected cells and present a molecule that is recognized by the immune system on the surface of the infected cell which attracts more immune fighting cells to the area. According to Lamb it is known that arginine is essential for the function of macrophages but until now no one realized that arginine has a much bigger role.

In their most recent work, Lamb and Mieulet presented arginine to a laboratory model. These models were better able to fight infection even if they were malnourished.

"This is a major work," said Lamb. "If this holds true in humans it shows that one aspect of nutrition that is critical is the level of amino acids."

The study, which is published in the August 17 edition of journal Science Signaling, has taken the research group from the University of Alberta three years.


Story Source:

The above story is based on materials provided by University of Alberta Faculty of Medicine & Dentistry. Note: Materials may be edited for content and length.


Journal Reference:

  1. V. Mieulet, L. Yan, C. Choisy, K. Sully, J. Procter, A. Kouroumalis, S. Krywawych, M. Pende, S. C. Ley, C. Moinard, R. F. Lamb. TPL-2-Mediated Activation of MAPK Downstream of TLR4 Signaling Is Coupled to Arginine Availability. Science Signaling, 2010; 3 (135): ra61 DOI: 10.1126/scisignal.2000934

Cite This Page:

University of Alberta Faculty of Medicine & Dentistry. "Why proper nutrition is so vital in fighting infection." ScienceDaily. ScienceDaily, 8 November 2010. <www.sciencedaily.com/releases/2010/08/100830192956.htm>.
University of Alberta Faculty of Medicine & Dentistry. (2010, November 8). Why proper nutrition is so vital in fighting infection. ScienceDaily. Retrieved November 24, 2014 from www.sciencedaily.com/releases/2010/08/100830192956.htm
University of Alberta Faculty of Medicine & Dentistry. "Why proper nutrition is so vital in fighting infection." ScienceDaily. www.sciencedaily.com/releases/2010/08/100830192956.htm (accessed November 24, 2014).

Share This


More From ScienceDaily



More Health & Medicine News

Monday, November 24, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Ebola-Hit Sierra Leone's Late Cocoa Leaves Bitter Taste

Ebola-Hit Sierra Leone's Late Cocoa Leaves Bitter Taste

AFP (Nov. 23, 2014) The arable district of Kenema in Sierra Leone -- at the centre of the Ebola outbreak in May -- has been under quarantine for three months as the cocoa harvest comes in. Duration: 01:32 Video provided by AFP
Powered by NewsLook.com
Don't Fall For Flu Shot Myths

Don't Fall For Flu Shot Myths

Newsy (Nov. 23, 2014) Misconceptions abound when it comes to your annual flu shot. Medical experts say most people older than 6 months should get the shot. Video provided by Newsy
Powered by NewsLook.com
WFP: Ebola Risks Heightened Among Women Throughout Africa

WFP: Ebola Risks Heightened Among Women Throughout Africa

AFP (Nov. 21, 2014) Having children has always been a frightening prospect in Sierra Leone, the world's most dangerous place to give birth, but Ebola has presented an alarming new threat for expectant mothers. Duration: 00:37 Video provided by AFP
Powered by NewsLook.com
Could Your Genes Be The Reason You're Single?

Could Your Genes Be The Reason You're Single?

Newsy (Nov. 21, 2014) Researchers in Beijing discovered a gene called 5-HTA1, and carriers are reportedly 20 percent more likely to be single. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins