Featured Research

from universities, journals, and other organizations

New TB diagnostic proves effective, expedient, study finds

Date:
September 2, 2010
Source:
NIH/National Institute of Allergy and Infectious Diseases
Summary:
A molecular test designed to easily diagnose tuberculosis (TB) and detect a drug-resistant form of the bacterium that causes TB can provide much more specific, sensitive and rapid results than currently available TB diagnostics, according to a new study.

A molecular test designed to easily diagnose tuberculosis (TB) and detect a drug-resistant form of the bacterium that causes TB can provide much more specific, sensitive and rapid results than currently available TB diagnostics, according to a new study in the New England Journal of Medicine.

In a test involving 1,730 patients with suspected drug-sensitive or multidrug-resistant pulmonary TB, the Xpert MTB/RIF TB test successfully identified 98 percent of all confirmed TB cases and 98 percent of patients with rifampin-resistant bacteria in less than two hours.

TB remains one of the major causes of disability and death worldwide, with an estimated 1.8 million deaths in 2008 and an increasing incidence of drug-resistant disease. New, less costly tools to rapidly diagnose TB and its drug-resistant forms are urgently needed to help stem the tide of new infections.

The National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, has supported the development of this diagnostics technology since 2002. This support was critical to the public-private partnership that led to the Xpert MTB/RIF TB test. The current clinical trial findings are from a study conducted by the Foundation for Innovative New Diagnostics (FIND), a Swiss-based nonprofit organization. NIAID currently supports a partnership project to expand the diagnostic system to detect other resistance markers for extensively drug-resistant TB.


Story Source:

The above story is based on materials provided by NIH/National Institute of Allergy and Infectious Diseases. Note: Materials may be edited for content and length.


Journal Reference:

  1. CC Boehme et al. Rapid molecular detection of tuberculosis and rifampin resistance. New England Journal of Medicine, 2010; DOI: 10.1056/NEJMoa0907847

Cite This Page:

NIH/National Institute of Allergy and Infectious Diseases. "New TB diagnostic proves effective, expedient, study finds." ScienceDaily. ScienceDaily, 2 September 2010. <www.sciencedaily.com/releases/2010/09/100901171559.htm>.
NIH/National Institute of Allergy and Infectious Diseases. (2010, September 2). New TB diagnostic proves effective, expedient, study finds. ScienceDaily. Retrieved September 30, 2014 from www.sciencedaily.com/releases/2010/09/100901171559.htm
NIH/National Institute of Allergy and Infectious Diseases. "New TB diagnostic proves effective, expedient, study finds." ScienceDaily. www.sciencedaily.com/releases/2010/09/100901171559.htm (accessed September 30, 2014).

Share This



More Health & Medicine News

Tuesday, September 30, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

How 'Yes Means Yes' Defines Sexual Assault

How 'Yes Means Yes' Defines Sexual Assault

Newsy (Sep. 29, 2014) Aimed at reducing sexual assaults on college campuses, California has adopted a new law changing the standard of consent for sexual activity. Video provided by Newsy
Powered by NewsLook.com
Scientists May Have Found An Early Sign Of Pancreatic Cancer

Scientists May Have Found An Early Sign Of Pancreatic Cancer

Newsy (Sep. 29, 2014) Researchers looked at 1,500 blood samples and determined people who developed pancreatic cancer had more branched chain amino acids. Video provided by Newsy
Powered by NewsLook.com
Colo. Doctors See Cluster of Enterovirus Cases

Colo. Doctors See Cluster of Enterovirus Cases

AP (Sep. 29, 2014) Doctors at the Children's Hospital of Colorado say they have treated over 4,000 children with serious respiratory illnesses since August. Nine of the patients have shown distinct neurological symptoms, including limb weakness. (Sept. 29) Video provided by AP
Powered by NewsLook.com
Dr.'s Unsure of Cause of Fast-Spreading Virus

Dr.'s Unsure of Cause of Fast-Spreading Virus

AP (Sep. 29, 2014) Doctors at the Children's Hospital of Colorado say they have treated over 4,000 children with serious respiratory illnesses since August. Nine of the patients have shown distinct neurological symptoms, including limb weakness. (Sept. 29) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins