Featured Research

from universities, journals, and other organizations

Secondary infections were a major cause of death during 1918 flu pandemic, research finds

Date:
November 2, 2010
Source:
NIH/National Institute of Allergy and Infectious Diseases
Summary:
Secondary infections with bacteria such as Streptococcus pneumoniae, which causes pneumonia, were a major cause of death during the 1918 flu pandemic and may be important in modern pandemics as well, according to a new article.

Secondary infections with bacteria such as Streptococcus pneumoniae, which causes pneumonia, were a major cause of death during the 1918 flu pandemic and may be important in modern pandemics as well, according to a new article in the Journal of Infectious Diseases co-authored by David M. Morens, M.D., senior advisor to the director of the National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health.

The researchers examined 13 studies published between 1918 and 1920. During this time, many scientists erroneously believed that influenza was caused by bacteria, not a virus. As a result, researchers began performing and publishing results from clinical trials testing bacterial vaccines designed to prevent the flu.

In their new study, Dr. Morens and his colleagues used modern statistical and evaluation methods to re-analyze the vaccine effectiveness data from these old studies in an attempt to correct for any statistical biases in the original analysis.

In addition to confirming the importance of bacterial infections associated with the 1918 influenza pandemic, the new analysis suggests that the use of bacterial vaccines containing S. pneumoniae could reduce pneumonia rates and deaths in modern influenza pandemics as well. During the 2009-2010 H1N1 influenza pandemic, the authors write, autopsy results implicated bacterial infections in 29 to 55 percent of deaths.

In light of this study, the authors recommend more research into the use of bacterial vaccines to prevent illness and death associated with influenza.


Story Source:

The above story is based on materials provided by NIH/National Institute of Allergy and Infectious Diseases. Note: Materials may be edited for content and length.


Journal Reference:

  1. Yu‐Wen Chien, KeithP. Klugman, DavidM. Morens. Efficacy of Whole‐Cell Killed Bacterial Vaccines in Preventing Pneumonia and Death during the 1918 Influenza Pandemic. The Journal of Infectious Diseases, 2010; DOI: 10.1086/657144

Cite This Page:

NIH/National Institute of Allergy and Infectious Diseases. "Secondary infections were a major cause of death during 1918 flu pandemic, research finds." ScienceDaily. ScienceDaily, 2 November 2010. <www.sciencedaily.com/releases/2010/11/101102130953.htm>.
NIH/National Institute of Allergy and Infectious Diseases. (2010, November 2). Secondary infections were a major cause of death during 1918 flu pandemic, research finds. ScienceDaily. Retrieved July 23, 2014 from www.sciencedaily.com/releases/2010/11/101102130953.htm
NIH/National Institute of Allergy and Infectious Diseases. "Secondary infections were a major cause of death during 1918 flu pandemic, research finds." ScienceDaily. www.sciencedaily.com/releases/2010/11/101102130953.htm (accessed July 23, 2014).

Share This




More Health & Medicine News

Wednesday, July 23, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Idaho Boy Helps Brother With Disabilities Complete Triathlon

Idaho Boy Helps Brother With Disabilities Complete Triathlon

Newsy (July 23, 2014) An 8-year-old boy helped his younger brother, who has a rare genetic condition that's confined him to a wheelchair, finish a triathlon. Video provided by Newsy
Powered by NewsLook.com
Thousands Who Can't Afford Medical Care Flock to Free US Clinic

Thousands Who Can't Afford Medical Care Flock to Free US Clinic

AFP (July 23, 2014) America may be the world’s richest country, but in terms of healthcare, the World Health Organisation ranks it 37th. Thousands turned out for a free clinic run by "Remote Area Medical" with a visit from the Governor of Virginia. Duration: 2:40 Video provided by AFP
Powered by NewsLook.com
Stone Fruit Listeria Scare Causes Sweeping Recall

Stone Fruit Listeria Scare Causes Sweeping Recall

Newsy (July 22, 2014) The Wawona Packing Company has issued a voluntary recall on the stone fruit it distributes due to a possible Listeria outbreak. Video provided by Newsy
Powered by NewsLook.com
Huge Schizophrenia Study Finds Dozens Of New Genetic Causes

Huge Schizophrenia Study Finds Dozens Of New Genetic Causes

Newsy (July 22, 2014) The 83 new genetic markers could open dozens of new avenues for schizophrenia treatment research. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins