Featured Research

from universities, journals, and other organizations

Secondary infections were a major cause of death during 1918 flu pandemic, research finds

Date:
November 2, 2010
Source:
NIH/National Institute of Allergy and Infectious Diseases
Summary:
Secondary infections with bacteria such as Streptococcus pneumoniae, which causes pneumonia, were a major cause of death during the 1918 flu pandemic and may be important in modern pandemics as well, according to a new article.

Secondary infections with bacteria such as Streptococcus pneumoniae, which causes pneumonia, were a major cause of death during the 1918 flu pandemic and may be important in modern pandemics as well, according to a new article in the Journal of Infectious Diseases co-authored by David M. Morens, M.D., senior advisor to the director of the National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health.

The researchers examined 13 studies published between 1918 and 1920. During this time, many scientists erroneously believed that influenza was caused by bacteria, not a virus. As a result, researchers began performing and publishing results from clinical trials testing bacterial vaccines designed to prevent the flu.

In their new study, Dr. Morens and his colleagues used modern statistical and evaluation methods to re-analyze the vaccine effectiveness data from these old studies in an attempt to correct for any statistical biases in the original analysis.

In addition to confirming the importance of bacterial infections associated with the 1918 influenza pandemic, the new analysis suggests that the use of bacterial vaccines containing S. pneumoniae could reduce pneumonia rates and deaths in modern influenza pandemics as well. During the 2009-2010 H1N1 influenza pandemic, the authors write, autopsy results implicated bacterial infections in 29 to 55 percent of deaths.

In light of this study, the authors recommend more research into the use of bacterial vaccines to prevent illness and death associated with influenza.


Story Source:

The above story is based on materials provided by NIH/National Institute of Allergy and Infectious Diseases. Note: Materials may be edited for content and length.


Journal Reference:

  1. Yu‐Wen Chien, KeithP. Klugman, DavidM. Morens. Efficacy of Whole‐Cell Killed Bacterial Vaccines in Preventing Pneumonia and Death during the 1918 Influenza Pandemic. The Journal of Infectious Diseases, 2010; DOI: 10.1086/657144

Cite This Page:

NIH/National Institute of Allergy and Infectious Diseases. "Secondary infections were a major cause of death during 1918 flu pandemic, research finds." ScienceDaily. ScienceDaily, 2 November 2010. <www.sciencedaily.com/releases/2010/11/101102130953.htm>.
NIH/National Institute of Allergy and Infectious Diseases. (2010, November 2). Secondary infections were a major cause of death during 1918 flu pandemic, research finds. ScienceDaily. Retrieved October 20, 2014 from www.sciencedaily.com/releases/2010/11/101102130953.htm
NIH/National Institute of Allergy and Infectious Diseases. "Secondary infections were a major cause of death during 1918 flu pandemic, research finds." ScienceDaily. www.sciencedaily.com/releases/2010/11/101102130953.htm (accessed October 20, 2014).

Share This



More Health & Medicine News

Monday, October 20, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

How Nigeria Beat Its Ebola Outbreak

How Nigeria Beat Its Ebola Outbreak

Newsy (Oct. 20, 2014) The World Health Organization has declared Nigeria free of Ebola. Health experts credit a bit of luck and the government's initial response. Video provided by Newsy
Powered by NewsLook.com
Another Study Suggests Viagra Is Good For The Heart

Another Study Suggests Viagra Is Good For The Heart

Newsy (Oct. 20, 2014) An ingredient in erectile-dysfunction medications such as Viagra could improve heart function. Perhaps not surprising, given Viagra's history. Video provided by Newsy
Powered by NewsLook.com
Ebola Worries End for Dozens on U.S. Watch Lists

Ebola Worries End for Dozens on U.S. Watch Lists

Reuters - US Online Video (Oct. 20, 2014) Forty-three people who had contact with Thomas Eric Duncan, the first person diagnosed with Ebola in the U.S., were cleared overnight of twice-daily monitoring after 21 days of showing no symptoms. Rough Cut (no reporter narration). Video provided by Reuters
Powered by NewsLook.com
CDC Calls for New Ebola Safety Guidelines

CDC Calls for New Ebola Safety Guidelines

AP (Oct. 20, 2014) Centers for Disease Control and Prevention Director Dr. Tom Frieden laid out new guidelines for health care workers when dealing with the deadly Ebola virus including new precautions when taking off personal protective equipment. (Oct. 20) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins