Featured Research

from universities, journals, and other organizations

Built-in timer for improving accuracy of cost saving paper-strip medical tests

Date:
November 4, 2010
Source:
American Chemical Society
Summary:
Scientists are reporting the development of a simple, built-in timer intended to improve the accuracy of paper tests and test strips for diagnosing diseases inexpensively at-home and elsewhere.

Paper-based diagnostic tests could become more accurate with a built-in timer that uses a color change signal (red dot at lower left) to indicate when test results are ready for analysis.
Credit: Scott T. Phillips

Scientists are reporting the development of a simple, built-in timer intended to improve the accuracy of paper tests and test strips for diagnosing diseases inexpensively at-home and elsewhere.

Related Articles


Their study appears in ACS' semi-monthly journal Analytical Chemistry.

Scott Phillips and Hyeran Noh note that so-called point-of-care tests include paper strip tests and others performed at home or bedside instead of in laboratories. They show special promise for improving medical care in developing countries and reducing health care costs elsewhere.

When fully developed, these low-cost paper tests may replace more expensive traditional tests for detecting biomarkers in urine, blood, and other body fluids, as well as for detecting pollution in water. Many types of tests that could be used on paper, however, require precise timing using a stopwatch to provide accurate results.

The authors cite as an example the CHEMCARD diagnostic test for measuring blood sugar or cholesterol in a drop of blood. It is almost 100 percent accurate when users view test results exactly 3 minutes after placing the drop of blood on the paper. Incorrect timing, however, cuts accuracy nearly in half. Patients (particularly those in the developing world), they indicate, may not have stopwatches or other timing devices, or may not use external timing devices with enough accuracy to obtain meaningful results.

The scientists describe the development of a built-in timer for paper-based diagnostic tests that eliminates the need for a stopwatch. The timer is made from a dye and the paraffin wax used in some candles. Addition of water, blood, urine or other body fluids starts the timer, and a color change signals when the time is up. The device has been modified to emit a buzz or other sound when the time is up, or even glow, the scientists note. When used with a test similar to the CHEMCARD glucose test, the timer was 97 percent accurate, slightly better than when a stopwatch was used.

The authors acknowledged funding from the Bill and Melinda Gates Foundation, the Arnold and Mabel Beckman Foundation, the Camille and Henry Dreyfus Foundation, 3M, Louis Martarano, and The Pennsylvania State University.


Story Source:

The above story is based on materials provided by American Chemical Society. Note: Materials may be edited for content and length.


Journal Reference:

  1. Hyeran Noh, Scott T. Phillips. Fluidic Timers for Time-Dependent, Point-of-Care Assays on Paper. Analytical Chemistry, 2010; 82 (19): 8071 DOI: 10.1021/ac1005537

Cite This Page:

American Chemical Society. "Built-in timer for improving accuracy of cost saving paper-strip medical tests." ScienceDaily. ScienceDaily, 4 November 2010. <www.sciencedaily.com/releases/2010/11/101103135346.htm>.
American Chemical Society. (2010, November 4). Built-in timer for improving accuracy of cost saving paper-strip medical tests. ScienceDaily. Retrieved April 1, 2015 from www.sciencedaily.com/releases/2010/11/101103135346.htm
American Chemical Society. "Built-in timer for improving accuracy of cost saving paper-strip medical tests." ScienceDaily. www.sciencedaily.com/releases/2010/11/101103135346.htm (accessed April 1, 2015).

Share This


More From ScienceDaily



More Health & Medicine News

Wednesday, April 1, 2015

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

7-Year-Old Girl Gets 3-D Printed 'robohand'

7-Year-Old Girl Gets 3-D Printed 'robohand'

AP (Mar. 31, 2015) — Although she never had much interest in prosthetic limbs before, Faith Lennox couldn&apos;t wait to slip on her new robohand. The 7-year-old, who lost part of her left arm when she was a baby, grabbed it as soon as it came off a 3-D printer. (March 31) Video provided by AP
Powered by NewsLook.com
Solitair Device Aims to Takes Guesswork out of Sun Safety

Solitair Device Aims to Takes Guesswork out of Sun Safety

Reuters - Innovations Video Online (Mar. 31, 2015) — The Solitair device aims to take the confusion out of how much sunlight we should expose our skin to. Small enough to be worn as a tie or hair clip, it monitors the user&apos;s sun exposure by taking into account their skin pigment, location and schedule. Matthew Stock reports. Video provided by Reuters
Powered by NewsLook.com
Soda, Salt and Sugar: The Next Generation of Taxes

Soda, Salt and Sugar: The Next Generation of Taxes

Washington Post (Mar. 30, 2015) — Denisa Livingston, a health advocate for the Dinι Community Advocacy Alliance, and the Post&apos;s Abby Phillip discuss efforts around the country to make unhealthy food choices hurt your wallet as much as your waistline. Video provided by Washington Post
Powered by NewsLook.com
UnitedHealth Buys Catamaran

UnitedHealth Buys Catamaran

Reuters - Business Video Online (Mar. 30, 2015) — The $12.8 billion merger will combine the U.S.&apos; third and fourth largest pharmacy benefit managers. Analysts say smaller PBMs could also merge. Fred Katayama reports. Video provided by Reuters
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:

Strange & Offbeat Stories

 

Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins