Featured Research

from universities, journals, and other organizations

Built-in timer for improving accuracy of cost saving paper-strip medical tests

Date:
November 4, 2010
Source:
American Chemical Society
Summary:
Scientists are reporting the development of a simple, built-in timer intended to improve the accuracy of paper tests and test strips for diagnosing diseases inexpensively at-home and elsewhere.

Paper-based diagnostic tests could become more accurate with a built-in timer that uses a color change signal (red dot at lower left) to indicate when test results are ready for analysis.
Credit: Scott T. Phillips

Scientists are reporting the development of a simple, built-in timer intended to improve the accuracy of paper tests and test strips for diagnosing diseases inexpensively at-home and elsewhere.

Their study appears in ACS' semi-monthly journal Analytical Chemistry.

Scott Phillips and Hyeran Noh note that so-called point-of-care tests include paper strip tests and others performed at home or bedside instead of in laboratories. They show special promise for improving medical care in developing countries and reducing health care costs elsewhere.

When fully developed, these low-cost paper tests may replace more expensive traditional tests for detecting biomarkers in urine, blood, and other body fluids, as well as for detecting pollution in water. Many types of tests that could be used on paper, however, require precise timing using a stopwatch to provide accurate results.

The authors cite as an example the CHEMCARD diagnostic test for measuring blood sugar or cholesterol in a drop of blood. It is almost 100 percent accurate when users view test results exactly 3 minutes after placing the drop of blood on the paper. Incorrect timing, however, cuts accuracy nearly in half. Patients (particularly those in the developing world), they indicate, may not have stopwatches or other timing devices, or may not use external timing devices with enough accuracy to obtain meaningful results.

The scientists describe the development of a built-in timer for paper-based diagnostic tests that eliminates the need for a stopwatch. The timer is made from a dye and the paraffin wax used in some candles. Addition of water, blood, urine or other body fluids starts the timer, and a color change signals when the time is up. The device has been modified to emit a buzz or other sound when the time is up, or even glow, the scientists note. When used with a test similar to the CHEMCARD glucose test, the timer was 97 percent accurate, slightly better than when a stopwatch was used.

The authors acknowledged funding from the Bill and Melinda Gates Foundation, the Arnold and Mabel Beckman Foundation, the Camille and Henry Dreyfus Foundation, 3M, Louis Martarano, and The Pennsylvania State University.


Story Source:

The above story is based on materials provided by American Chemical Society. Note: Materials may be edited for content and length.


Journal Reference:

  1. Hyeran Noh, Scott T. Phillips. Fluidic Timers for Time-Dependent, Point-of-Care Assays on Paper. Analytical Chemistry, 2010; 82 (19): 8071 DOI: 10.1021/ac1005537

Cite This Page:

American Chemical Society. "Built-in timer for improving accuracy of cost saving paper-strip medical tests." ScienceDaily. ScienceDaily, 4 November 2010. <www.sciencedaily.com/releases/2010/11/101103135346.htm>.
American Chemical Society. (2010, November 4). Built-in timer for improving accuracy of cost saving paper-strip medical tests. ScienceDaily. Retrieved July 28, 2014 from www.sciencedaily.com/releases/2010/11/101103135346.htm
American Chemical Society. "Built-in timer for improving accuracy of cost saving paper-strip medical tests." ScienceDaily. www.sciencedaily.com/releases/2010/11/101103135346.htm (accessed July 28, 2014).

Share This




More Health & Medicine News

Monday, July 28, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

$15B Deal on Vets' Health Care Reached

$15B Deal on Vets' Health Care Reached

AP (July 28, 2014) A bipartisan deal to improve veterans health care would authorize at least $15 billion in emergency spending to fix a veterans program scandalized by long patient wait times and falsified records. (July 28) Video provided by AP
Powered by NewsLook.com
Traditional African Dishes Teach Healthy Eating

Traditional African Dishes Teach Healthy Eating

AP (July 28, 2014) Classes are being offered nationwide to encourage African Americans to learn about cooking fresh foods based on traditional African cuisine. The program is trying to combat obesity, heart disease and other ailments often linked to diet. (July 28) Video provided by AP
Powered by NewsLook.com
West Africa Gripped by Deadly Ebola Outbreak

West Africa Gripped by Deadly Ebola Outbreak

AFP (July 28, 2014) The worst-ever outbreak of the deadly Ebola epidemic grips west Africa, killing hundreds. Duration: 00:48 Video provided by AFP
Powered by NewsLook.com
Trees Could Save More Than 850 Lives Each Year

Trees Could Save More Than 850 Lives Each Year

Newsy (July 27, 2014) A national study conducted by the USDA Forest Service found that trees collectively save more than 850 lives on an annual basis. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins