Featured Research

from universities, journals, and other organizations

Pre-injury exercise may mitigate the effects of traumatic brain injury in mice

Date:
November 28, 2010
Source:
Society for Neuroscience
Summary:
Being physically fit before a traumatic brain injury (TBI) might improve recovery, preliminary findings suggest. After TBI, mice bred for running behavior exhibited smaller brain lesions and engaged in more extensive post-injury activity than did mice that had been sedentary before the injury.

Being physically fit before a traumatic brain injury (TBI) might improve recovery, preliminary findings suggest. After TBI, mice bred for running behavior exhibited smaller brain lesions and engaged in more extensive post-injury activity than did mice that had been sedentary before the injury.

The research was presented at Neuroscience 2010, the annual meeting of the Society for Neuroscience, held in San Diego.

Engaging in physical exercise after TBI is known to improve cognitive outcome. "Our findings suggest that people who are already physically fit will have a better recovery profile than sedentary people," said senior author Jerome Badaut, PhD, at Loma Linda University.

In a preliminary study, Badaut and his colleagues compared four mice genetically selected for running behavior with five control mice. The runner mice were allowed to run on wheels for two weeks before undergoing a procedure that mimics a TBI; the sedentary mice were not.

Magnetic resonance imaging revealed that the brain lesions in the exercising mice were 34 percent smaller in volume than those in the sedentary mice. In addition, the exercising mice spent more time on a balance beam task, indicating that the smaller lesions contributed to improved behavior. They also gradually increased their activity after injury, while the sedentary mice decreased theirs.

Research supported by the Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Science Foundation, Department of Defense, and the Swiss National Science Foundation.


Story Source:

The above story is based on materials provided by Society for Neuroscience. Note: Materials may be edited for content and length.


Cite This Page:

Society for Neuroscience. "Pre-injury exercise may mitigate the effects of traumatic brain injury in mice." ScienceDaily. ScienceDaily, 28 November 2010. <www.sciencedaily.com/releases/2010/11/101116100457.htm>.
Society for Neuroscience. (2010, November 28). Pre-injury exercise may mitigate the effects of traumatic brain injury in mice. ScienceDaily. Retrieved July 29, 2014 from www.sciencedaily.com/releases/2010/11/101116100457.htm
Society for Neuroscience. "Pre-injury exercise may mitigate the effects of traumatic brain injury in mice." ScienceDaily. www.sciencedaily.com/releases/2010/11/101116100457.htm (accessed July 29, 2014).

Share This




More Plants & Animals News

Tuesday, July 29, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Deadly Ebola Virus Threatens West Africa

Deadly Ebola Virus Threatens West Africa

AP (July 28, 2014) West African nations and international health organizations are working to contain the largest Ebola outbreak in history. It's one of the deadliest diseases known to man, but the CDC says it's unlikely to spread in the U.S. (July 28) Video provided by AP
Powered by NewsLook.com
Traditional African Dishes Teach Healthy Eating

Traditional African Dishes Teach Healthy Eating

AP (July 28, 2014) Classes are being offered nationwide to encourage African Americans to learn about cooking fresh foods based on traditional African cuisine. The program is trying to combat obesity, heart disease and other ailments often linked to diet. (July 28) Video provided by AP
Powered by NewsLook.com
Asteroid's Timing Was 'Colossal Bad Luck' For The Dinosaurs

Asteroid's Timing Was 'Colossal Bad Luck' For The Dinosaurs

Newsy (July 28, 2014) The asteroid that killed the dinosaurs struck at the worst time for them. A new study says that if it hit earlier or later, they might've survived. Video provided by Newsy
Powered by NewsLook.com
Raw: Sea Turtle Hatchlings Emerge from Nest

Raw: Sea Turtle Hatchlings Emerge from Nest

AP (July 27, 2014) A live-streaming webcam catches loggerhead sea turtle hatchlings emerging from a nest in the Florida Keys. (July 27) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins