Featured Research

from universities, journals, and other organizations

Influenza vaccines of the future

Date:
November 18, 2010
Source:
NIH/National Institute of Allergy and Infectious Diseases
Summary:
New research examines the limitations of currently available influenza vaccines and offers direction for developing more efficient and reliable strategies to make vaccines to protect against seasonal as well as pandemic influenza.

In a review article appearing in the New England Journal of Medicine, scientists at the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, examine research under way to address the limitations of currently available influenza vaccines and develop more efficient and reliable strategies to make vaccines to protect against seasonal as well as pandemic influenza.

Although licensed seasonal flu vaccines safely and effectively protect most people who receive them from illness and death, the degree of protection varies depending on how well the circulating virus strains and those in the vaccine match. A vaccine recipient's age and health status also can affect the effectiveness of influenza vaccination.

The authors discuss the spectrum of ongoing influenza vaccine research that may transform the field in decades to come. Efforts to grow the vaccine virus in cells rather than eggs are currently under way and there is consideration of the addition to influenza vaccine of immune-stimulating adjuvants to be used in certain groups of individuals. Other approaches under development include influenza vaccines based on recombinant virus proteins, non-infectious virus-like particles, harmless vectors or influenza DNA. Also under intense study is the ultimate goal, a so-called universal flu vaccine that would provide protection against multiple strains of influenza, reducing the need for yearly flu shots while simultaneously protecting against novel flu viruses that may arise in the future.

To further protect vulnerable populations such as the elderly and those with underlying chronic diseases from seasonal influenza, as well as to quickly control the spread of potential pandemic influenza viruses, influenza vaccine makers of the future must employ novel production technologies, the authors note.


Story Source:

The above story is based on materials provided by NIH/National Institute of Allergy and Infectious Diseases. Note: Materials may be edited for content and length.


Journal Reference:

  1. Linda C. Lambert, Ph.D., and Anthony S. Fauci, M.D. Influenza Vaccines for the Future. N Engl J Med, 2010; 363:2036-2044; November 18, 2010 DOI: 10.1056/ NEJMra1002842

Cite This Page:

NIH/National Institute of Allergy and Infectious Diseases. "Influenza vaccines of the future." ScienceDaily. ScienceDaily, 18 November 2010. <www.sciencedaily.com/releases/2010/11/101117184403.htm>.
NIH/National Institute of Allergy and Infectious Diseases. (2010, November 18). Influenza vaccines of the future. ScienceDaily. Retrieved July 23, 2014 from www.sciencedaily.com/releases/2010/11/101117184403.htm
NIH/National Institute of Allergy and Infectious Diseases. "Influenza vaccines of the future." ScienceDaily. www.sciencedaily.com/releases/2010/11/101117184403.htm (accessed July 23, 2014).

Share This




More Health & Medicine News

Wednesday, July 23, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Courts Conflicted Over Healthcare Law

Courts Conflicted Over Healthcare Law

AP (July 22, 2014) Two federal appeals courts issued conflicting rulings Tuesday on the legality of the federally-run healthcare exchange that operates in 36 states. (July 22) Video provided by AP
Powered by NewsLook.com
Why Do People Believe We Only Use 10 Percent Of Our Brains?

Why Do People Believe We Only Use 10 Percent Of Our Brains?

Newsy (July 22, 2014) The new sci-fi thriller "Lucy" is making people question whether we really use all our brainpower. But, as scientists have insisted for years, we do. Video provided by Newsy
Powered by NewsLook.com
Scientists Find New Way To Make Human Platelets

Scientists Find New Way To Make Human Platelets

Newsy (July 22, 2014) Boston scientists have discovered a new way to create fully functioning human platelets using a bioreactor and human stem cells. Video provided by Newsy
Powered by NewsLook.com
Gilead's $1000-a-Pill Drug Could Cure Hep C in HIV-Positive People

Gilead's $1000-a-Pill Drug Could Cure Hep C in HIV-Positive People

TheStreet (July 21, 2014) New research shows Gilead Science's drug Sovaldi helps in curing hepatitis C in those who suffer from HIV. In a medical study, the combination of Gilead's Hep C drug with anti-viral drug Ribavirin cured 76% of HIV-positive patients suffering from the most common hepatitis C strain. Hepatitis C and related complications have been a top cause of death in HIV-positive patients. Typical medication used to treat the disease, including interferon proteins, tended to react badly with HIV drugs. However, Sovaldi's %1,000-a-pill price tag could limit the number of patients able to access the treatment. TheStreet's Keris Lahiff reports from New York. Video provided by TheStreet
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins