The new compounds have show promise against the Mycobacterium bacterium tuberculosis.
Credit: CDC/George P. Kubica
A team of researchers from Spain and Latin America have synthesized two iron compounds that inhibit the in vitro growth of Mycobacterium tuberculosis, the bacteria that causes tuberculosis. Due their low level of toxicity in mammal cells, the compounds could be used in the future as therapeutic agents and hospital disinfectants.
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- M. Belιn Tarallo, Carolina Urquiola, Antonio Monge, Beatriz Parajσn Costa, Ronny R. Ribeiro, Antonio J. Costa-Filho, Roberto C. Mercader, Fernando R. Pavan, Clarice Q.F. Leite, Marνa H. Torre. Design of novel iron compounds as potential therapeutic agents against tuberculosis☆. Journal of Inorganic Biochemistry, 2010; 104 (11): 1164 DOI: 10.1016/j.jinorgbio.2010.07.005
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Plataforma SINC. "Iron compounds synthesized to combat tuberculosis." ScienceDaily. ScienceDaily, 29 November 2010. <www.sciencedaily.com/releases/2010/11/101126094446.htm>.
Plataforma SINC. (2010, November 29). Iron compounds synthesized to combat tuberculosis. ScienceDaily. Retrieved April 17, 2014 from www.sciencedaily.com/releases/2010/11/101126094446.htm
Plataforma SINC. "Iron compounds synthesized to combat tuberculosis." ScienceDaily. www.sciencedaily.com/releases/2010/11/101126094446.htm (accessed April 17, 2014).