Featured Research

from universities, journals, and other organizations

New high-resolution method for imaging below the skin using a liquid lens

Date:
February 20, 2011
Source:
University of Rochester
Summary:
New optical technology provides unprecedented images under the skin's surface. The aim of the technology is to detect and examine skin lesions to determine whether they are benign or cancerous without having to cut the suspected tumor out of the skin and analyze it in the lab.

This prototype device developed by University of Rochester Professor of Optical Engineering Jannick Rolland can take high-resolution images under the skin's surface without removing the skin. Researchers say that in the future it may eliminate the need for many biopsies to detect skin cancer.
Credit: J. Adam Fenster

University of Rochester optics professor Jannick Rolland has developed an optical technology that provides unprecedented images under the skin's surface. The aim of the technology is to detect and examine skin lesions to determine whether they are benign or cancerous without having to cut the suspected tumor out of the skin and analyze it in the lab. Instead, the tip of a roughly one-foot-long cylindrical probe is placed in contact with the tissue, and within seconds a clear, high-resolution, 3D image of what lies below the surface emerges.

Related Articles


Rolland presented her findings at the 2011 annual meeting of the American Association for the Advancement of Science in Washington, D.C., on Feb. 19.

"My hope is that, in the future, this technology could remove significant inconvenience and expense from the process of skin lesion diagnosis," Rolland says. "When a patient walks into a clinic with a suspicious mole, for instance, they wouldn't have to have it necessarily surgically cut out of their skin or be forced to have a costly and time-consuming MRI done. Instead, a relatively small, portable device could take an image that will assist in the classification of the lesion right in the doctor's office."

The device accomplishes this using a unique liquid lens setup developed by Rolland and her team for a process known as Optical Coherence Microscopy. In a liquid lens, a droplet of water takes the place of the glass in a standard lens. As the electrical field around the water droplet changes, the droplet changes its shape and therefore changes the focus of the lens. This allows the device to take thousands of pictures focused at different depths below the skin's surface. Combining these images creates a fully in-focus image of all of the tissue up to 1 millimeter deep in human skin, which includes important skin tissue structures. Because the device uses near infrared light instead of ultrasounds, the images have a precise, micron-scale resolution instead of a millimeter-scale resolution.

The process has been successfully tested in in-vivo human skin and several papers on it have been published in peer-reviewed journals. Rolland says that the next step is to start using it in a clinical research environment so its ability to discriminate between different types of lesions may be assessed.

Rolland joined the faculty of the Hajim School of Engineering and Applied Science's Institute of Optics in 2009. She is the Brian J. Thompson Professor of Optical Engineering and is also a professor of biomedical engineering and associate director of the R.E. Hopkins Center for Optical Design and Engineering.


Story Source:

The above story is based on materials provided by University of Rochester. Note: Materials may be edited for content and length.


Cite This Page:

University of Rochester. "New high-resolution method for imaging below the skin using a liquid lens." ScienceDaily. ScienceDaily, 20 February 2011. <www.sciencedaily.com/releases/2011/02/110219160003.htm>.
University of Rochester. (2011, February 20). New high-resolution method for imaging below the skin using a liquid lens. ScienceDaily. Retrieved November 28, 2014 from www.sciencedaily.com/releases/2011/02/110219160003.htm
University of Rochester. "New high-resolution method for imaging below the skin using a liquid lens." ScienceDaily. www.sciencedaily.com/releases/2011/02/110219160003.htm (accessed November 28, 2014).

Share This


More From ScienceDaily



More Health & Medicine News

Friday, November 28, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Rural India's Low-Cost Sanitary Pad Revolution

Rural India's Low-Cost Sanitary Pad Revolution

AFP (Nov. 28, 2014) — One man hopes his invention -– a machine that produces cheap sanitary pads –- will help empower Indian women. Duration: 01:51 Video provided by AFP
Powered by NewsLook.com
Research on Bats Could Help Develop Drugs Against Ebola

Research on Bats Could Help Develop Drugs Against Ebola

AFP (Nov. 28, 2014) — In Africa's only biosafety level 4 laboratory, scientists have been carrying out experiments on bats to understand how virus like Ebola are being transmitted, and how some of them resist to it. Duration: 01:18 Video provided by AFP
Powered by NewsLook.com
Ebola Leaves Orphans Alone in Sierra Leone

Ebola Leaves Orphans Alone in Sierra Leone

AFP (Nov. 27, 2014) — The Ebola epidemic sweeping Sierra Leone is having a profound effect on the country's children, many of whom have been left without any family members to support them. Duration: 01:02 Video provided by AFP
Powered by NewsLook.com
Experimental Ebola Vaccine Shows Promise In Human Trial

Experimental Ebola Vaccine Shows Promise In Human Trial

Newsy (Nov. 27, 2014) — A recent test of a prototype Ebola vaccine generated an immune response to the disease in subjects. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:

Strange & Offbeat Stories

 

Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins