Featured Research

from universities, journals, and other organizations

Probiotic identified to treat ulcers

Date:
February 24, 2011
Source:
American Society for Microbiology
Summary:
Researchers have identified a strain of probiotic bacteria that may be useful in treating ulcers caused by Helicobacter pylori.

Researchers from Spain have identified a strain of probiotic bacteria that may be useful in treating ulcers caused by Helicobacter pylori. They report their findings in the February 2011 issue of the journal Applied and Environmental Microbiology.

"H. pylori is considered one of the major risk factors underlying the development of gastritis and gastric and duodenal ulcers," write the researchers. "Currently, antibiotic-based treatment for H. pylori infection is neither sufficient nor satisfactory, with the most successful treatments reaching 75 to 90% eradication rates. The use of probiotics is a potentially promising tool to prevent H. pylori."

According to an expert consultation conducted by the Food and Agriculture Organization and the World Health Organization probiotics are "live microorganisms which when administered in adequate amounts confer a health benefit to the host." The regular intake of probiotic microoganisms has been demonstrated to prevent several disorders including diarrhea and inflammatory bowel disease.

Among probiotics Bifidobacterium is one of the favorite genera in studies focused on the prevention of gastrointestinal infection and is often used in fermented dairy products or food supplements. Some studies have been done in vitro (in test tubes or petri dishes) showing bifidobacterial activity against H. pylori.

In this study, the researchers tested numerous strains of bifidobacteria isolated from the feces of breast-fed infants for activity against H. pylori. They identified one strain (Bifidobacterium bifidum CECT 7366) that under certain conditions had an inhibition level of nearly 95% in vitro and tested its activity against infection in mice.

After 21 days, mice treated with the potentially probiotic strain developed significantly fewer ulcers than the control group. Additional tests suggest that treatment partially relieved damage to gastric tissue caused by H. pylori infection. Ingestion of the bacteria did not induce any disease or mortality in both healthy and immunocompromised mice.

"The results presented here confer to strain B. bifidum CECT 7366 the status of a probiotic bacterium with functional activity against H. pylori," write the researchers. "Human clinical trials must be performed before commercialization of this strain can be approved."


Story Source:

The above story is based on materials provided by American Society for Microbiology. Note: Materials may be edited for content and length.


Journal Reference:

  1. E. Chenoll, B. Casinos, E. Bataller, P. Astals, J. Echevarria, J. R. Iglesias, P. Balbarie, D. Ramon, S. Genoves. Novel Probiotic Bifidobacterium bifidum CECT 7366 Strain Active against the Pathogenic Bacterium Helicobacter pylori. Applied and Environmental Microbiology, 2010; 77 (4): 1335 DOI: 10.1128/AEM.01820-10

Cite This Page:

American Society for Microbiology. "Probiotic identified to treat ulcers." ScienceDaily. ScienceDaily, 24 February 2011. <www.sciencedaily.com/releases/2011/02/110224121905.htm>.
American Society for Microbiology. (2011, February 24). Probiotic identified to treat ulcers. ScienceDaily. Retrieved July 31, 2014 from www.sciencedaily.com/releases/2011/02/110224121905.htm
American Society for Microbiology. "Probiotic identified to treat ulcers." ScienceDaily. www.sciencedaily.com/releases/2011/02/110224121905.htm (accessed July 31, 2014).

Share This




More Health & Medicine News

Thursday, July 31, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Health Insurers' Profits Slide

Health Insurers' Profits Slide

Reuters - Business Video Online (July 30, 2014) Obamacare-related costs were said to be behind the profit plunge at Wellpoint and Humana, but Wellpoint sees the new exchanges boosting its earnings for the full year. Fred Katayama reports. Video provided by Reuters
Powered by NewsLook.com
Concern Grows Over Worsening Ebola Crisis

Concern Grows Over Worsening Ebola Crisis

AFP (July 30, 2014) Pan-African airline ASKY has suspended all flights to and from the capitals of Liberia and Sierra Leone amid the worsening Ebola health crisis, which has so far caused 672 deaths in Guinea, Liberia and Sierra Leone. Duration: 00:43 Video provided by AFP
Powered by NewsLook.com
At Least 20 Chikungunya Cases in New Jersey

At Least 20 Chikungunya Cases in New Jersey

AP (July 30, 2014) At least 20 New Jersey residents have tested positive for chikungunya, a mosquito-borne virus that has spread through the Caribbean. (July 30) Video provided by AP
Powered by NewsLook.com
Xtreme Eating: Your Daily Caloric Intake All On One Plate

Xtreme Eating: Your Daily Caloric Intake All On One Plate

Newsy (July 30, 2014) The Center for Science in the Public Interest released its 2014 list of single meals with whopping calorie counts. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

    Environment News

    Technology News



      Save/Print:
      Share:

      Free Subscriptions


      Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

      Get Social & Mobile


      Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

      Have Feedback?


      Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
      Mobile: iPhone Android Web
      Follow: Facebook Twitter Google+
      Subscribe: RSS Feeds Email Newsletters
      Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins