Featured Research

from universities, journals, and other organizations

Fish oil fights weight loss due to chemotherapy

Date:
February 28, 2011
Source:
Wiley-Blackwell
Summary:
A new analysis has found that supplementing the diet with fish oil may prevent muscle and weight loss that commonly occurs in cancer patients who undergo chemotherapy. The study indicates that fish oil may help combat cancer-related malnutrition.

A new analysis has found that supplementing the diet with fish oil may prevent muscle and weight loss that commonly occurs in cancer patients who undergo chemotherapy. Published early online in Cancer, a peer-reviewed journal of the American Cancer Society, the study indicates that fish oil may help combat cancer-related malnutrition.

Related Articles


Chemotherapy can cause cancer patients to lose muscle mass and become malnourished, leading to fatigue, a decreased quality of life, an inability to receive necessary treatments, and shorter survival.

Researchers suspect that supplementing the diet with fish oil -- which contains omega-3 fatty acids such as eicosapentaenoic acid -- may help patients maintain or gain muscle. To test the hypothesis, Vera Mazurak, PhD, of the University of Alberta in Edmonton, Canada, led a team that compared the effects of fish oil with that of standard care (no intervention) on weight, muscle, and fat tissue in newly referred non-small cell lung cancer patients.

The trial involved 16 patients who took fish oil (2.2 grams of eicosapentaenoic acid/day) and 24 patients who did not. The study ran until patients completed their first-line (initial) chemotherapy treatments, which lasted about 10 weeks. Muscle and fat were periodically measured using computed tomography images. Blood was collected and weight was recorded at the start of the study and throughout chemotherapy.

Patients who did not take fish oil lost an average of 2.3 kilograms whereas patients receiving fish oil maintained their weight. Patients with the greatest increase in eicosapentaenoic acid concentration in the blood following fish oil supplementation had the greatest gains in muscle. Sixty-nine percent of patients in the fish oil group gained or maintained muscle mass. Comparatively, only 29 percent of patients in the standard care group maintained muscle mass, and overall, patients in this group lost 1 kilogram of muscle. No difference in total fat tissue was observed between the two groups.

The authors concluded that nutritional intervention with two grams of fish oil per day provides a benefit over standard care, allowing patients to maintain their weight and muscle mass during chemotherapy. "Fish oil may prevent loss of weight and muscle by interfering with some of the pathways that are altered in advanced cancer," said Dr. Mazurak. "This holds great promise because currently there is no effective treatment for cancer-related malnutrition," she added. Dr. Mazurak noted that fish oil is safe and non-toxic with virtually no side effects. It may be beneficial to patients with other forms of cancer and other chronic diseases that are associated with malnutrition, as well as to elderly individuals who are at risk for muscle loss.


Story Source:

The above story is based on materials provided by Wiley-Blackwell. Note: Materials may be edited for content and length.


Cite This Page:

Wiley-Blackwell. "Fish oil fights weight loss due to chemotherapy." ScienceDaily. ScienceDaily, 28 February 2011. <www.sciencedaily.com/releases/2011/02/110228090202.htm>.
Wiley-Blackwell. (2011, February 28). Fish oil fights weight loss due to chemotherapy. ScienceDaily. Retrieved December 21, 2014 from www.sciencedaily.com/releases/2011/02/110228090202.htm
Wiley-Blackwell. "Fish oil fights weight loss due to chemotherapy." ScienceDaily. www.sciencedaily.com/releases/2011/02/110228090202.htm (accessed December 21, 2014).

Share This


More From ScienceDaily



More Health & Medicine News

Sunday, December 21, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

The Best Tips to Curb Holiday Carbs

The Best Tips to Curb Holiday Carbs

Buzz60 (Dec. 19, 2014) It's hard to resist those delicious but fattening carbs we all crave during the winter months, but there are some ways to stay satisfied without consuming the extra calories. Vanessa Freeman (@VanessaFreeTV) has the details. Video provided by Buzz60
Powered by NewsLook.com
Sierra Leone Bikers Spread the Message to Fight Ebola

Sierra Leone Bikers Spread the Message to Fight Ebola

AFP (Dec. 19, 2014) More than 100 motorcyclists hit the road to spread awareness messages about Ebola. Nearly 7,000 people have now died from the virus, almost all of them in west Africa, according to the World Health Organization. Video provided by AFP
Powered by NewsLook.com
Researchers Test Colombian Village With High Alzheimer's Rates

Researchers Test Colombian Village With High Alzheimer's Rates

AFP (Dec. 19, 2014) In Yarumal, a village in N. Colombia, Alzheimer's has ravaged a disproportionately large number of families. A genetic "curse" that may pave the way for research on how to treat the disease that claims a new victim every four seconds. Duration: 02:42 Video provided by AFP
Powered by NewsLook.com
The Best Protein-Filled Foods to Energize You for the New Year

The Best Protein-Filled Foods to Energize You for the New Year

Buzz60 (Dec. 19, 2014) The new year is coming and nothing will energize you more for 2015 than protein-filled foods. Fitness and nutrition expert John Basedow (@JohnBasedow) gives his favorite high protein foods that will help you build muscle, lose fat and have endless energy. Video provided by Buzz60
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins