Featured Research

from universities, journals, and other organizations

Fish oil fights weight loss due to chemotherapy

Date:
February 28, 2011
Source:
Wiley-Blackwell
Summary:
A new analysis has found that supplementing the diet with fish oil may prevent muscle and weight loss that commonly occurs in cancer patients who undergo chemotherapy. The study indicates that fish oil may help combat cancer-related malnutrition.

A new analysis has found that supplementing the diet with fish oil may prevent muscle and weight loss that commonly occurs in cancer patients who undergo chemotherapy. Published early online in Cancer, a peer-reviewed journal of the American Cancer Society, the study indicates that fish oil may help combat cancer-related malnutrition.

Related Articles


Chemotherapy can cause cancer patients to lose muscle mass and become malnourished, leading to fatigue, a decreased quality of life, an inability to receive necessary treatments, and shorter survival.

Researchers suspect that supplementing the diet with fish oil -- which contains omega-3 fatty acids such as eicosapentaenoic acid -- may help patients maintain or gain muscle. To test the hypothesis, Vera Mazurak, PhD, of the University of Alberta in Edmonton, Canada, led a team that compared the effects of fish oil with that of standard care (no intervention) on weight, muscle, and fat tissue in newly referred non-small cell lung cancer patients.

The trial involved 16 patients who took fish oil (2.2 grams of eicosapentaenoic acid/day) and 24 patients who did not. The study ran until patients completed their first-line (initial) chemotherapy treatments, which lasted about 10 weeks. Muscle and fat were periodically measured using computed tomography images. Blood was collected and weight was recorded at the start of the study and throughout chemotherapy.

Patients who did not take fish oil lost an average of 2.3 kilograms whereas patients receiving fish oil maintained their weight. Patients with the greatest increase in eicosapentaenoic acid concentration in the blood following fish oil supplementation had the greatest gains in muscle. Sixty-nine percent of patients in the fish oil group gained or maintained muscle mass. Comparatively, only 29 percent of patients in the standard care group maintained muscle mass, and overall, patients in this group lost 1 kilogram of muscle. No difference in total fat tissue was observed between the two groups.

The authors concluded that nutritional intervention with two grams of fish oil per day provides a benefit over standard care, allowing patients to maintain their weight and muscle mass during chemotherapy. "Fish oil may prevent loss of weight and muscle by interfering with some of the pathways that are altered in advanced cancer," said Dr. Mazurak. "This holds great promise because currently there is no effective treatment for cancer-related malnutrition," she added. Dr. Mazurak noted that fish oil is safe and non-toxic with virtually no side effects. It may be beneficial to patients with other forms of cancer and other chronic diseases that are associated with malnutrition, as well as to elderly individuals who are at risk for muscle loss.


Story Source:

The above story is based on materials provided by Wiley-Blackwell. Note: Materials may be edited for content and length.


Cite This Page:

Wiley-Blackwell. "Fish oil fights weight loss due to chemotherapy." ScienceDaily. ScienceDaily, 28 February 2011. <www.sciencedaily.com/releases/2011/02/110228090202.htm>.
Wiley-Blackwell. (2011, February 28). Fish oil fights weight loss due to chemotherapy. ScienceDaily. Retrieved November 23, 2014 from www.sciencedaily.com/releases/2011/02/110228090202.htm
Wiley-Blackwell. "Fish oil fights weight loss due to chemotherapy." ScienceDaily. www.sciencedaily.com/releases/2011/02/110228090202.htm (accessed November 23, 2014).

Share This


More From ScienceDaily



More Health & Medicine News

Sunday, November 23, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

WFP: Ebola Risks Heightened Among Women Throughout Africa

WFP: Ebola Risks Heightened Among Women Throughout Africa

AFP (Nov. 21, 2014) Having children has always been a frightening prospect in Sierra Leone, the world's most dangerous place to give birth, but Ebola has presented an alarming new threat for expectant mothers. Duration: 00:37 Video provided by AFP
Powered by NewsLook.com
Could Your Genes Be The Reason You're Single?

Could Your Genes Be The Reason You're Single?

Newsy (Nov. 21, 2014) Researchers in Beijing discovered a gene called 5-HTA1, and carriers are reportedly 20 percent more likely to be single. Video provided by Newsy
Powered by NewsLook.com
Raw: Paralyzed Marine Walks With Robotic Braces

Raw: Paralyzed Marine Walks With Robotic Braces

AP (Nov. 21, 2014) Marine Corps officials say a special operations officer left paralyzed by a sniper's bullet in Afghanistan walked using robotic leg braces in a ceremony to award him a Bronze Star. (Nov. 21) Video provided by AP
Powered by NewsLook.com
Milestone Birthdays Can Bring Existential Crisis, Study Says

Milestone Birthdays Can Bring Existential Crisis, Study Says

Newsy (Nov. 21, 2014) Researchers find that as people approach new decades in their lives they make bigger life decisions. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins