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Vitamin D deficiency in cirrhosis

Date:
March 16, 2011
Source:
World Journal of Gastroenterology
Summary:
A research team from Denmark examined the vitamin D status in patients with alcoholic cirrhosis compared to those with primary biliary cirrhosis. They found that vitamin D deficiency in cirrhosis relates to liver dysfunction rather than etiology, with lower levels of vitamin D in alcoholic cirrhosis than in primary biliary cirrhosis.

Vitamin D deficiency is a well reported complication in chronic cholestatic liver disease such as primary biliary cirrhosis. While the prevalence and treatment of this deficiency has been addressed in many articles over the last decades, little is known of the vitamin D status in alcoholic liver cirrhosis.

A research article published on February 21, 2011 in the World Journal of Gastroenterology addresses this question. The authors described the serum vitamin D status in a retrospective case series of patients with alcoholic liver cirrhosis compared to those with primary biliary cirrhosis.

The study showed that vitamin D deficiency is more frequent and severe in patients with alcoholic liver cirrhosis than in patients with primary biliary cirrhosis. Furthermore, it indicated that the degree of liver dysfunction, rather than the aetiology of cirrhosis, dictates the risk of vitamin D deficiency.

This study emphasizes the importance of monitoring vitamin D levels in all patients with cirrhosis. However, further studies are needed to find the most favourable form of vitamin D supplementation for these patients.


Story Source:

The above story is based on materials provided by World Journal of Gastroenterology. Note: Materials may be edited for content and length.


Journal Reference:

  1. Malham M, Jψrgensen SP, Ott P, Agnholt J, Vilstrup H, Borre M, Dahlerup JF. Vitamin D deficiency in cirrhosis relates to liver dysfunction rather than aetiology. World Journal of Gastroenterology, 2011; 17 (7): 922 DOI: 10.3748/wjg.v17.i7.922

Cite This Page:

World Journal of Gastroenterology. "Vitamin D deficiency in cirrhosis." ScienceDaily. ScienceDaily, 16 March 2011. <www.sciencedaily.com/releases/2011/03/110315103547.htm>.
World Journal of Gastroenterology. (2011, March 16). Vitamin D deficiency in cirrhosis. ScienceDaily. Retrieved September 1, 2014 from www.sciencedaily.com/releases/2011/03/110315103547.htm
World Journal of Gastroenterology. "Vitamin D deficiency in cirrhosis." ScienceDaily. www.sciencedaily.com/releases/2011/03/110315103547.htm (accessed September 1, 2014).

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