Featured Research

from universities, journals, and other organizations

Streptococcus enzyme could compete with toothbrushes, dental floss

Date:
March 22, 2011
Source:
American Society for Microbiology
Summary:
Investigators from Japan show in vitro that the bacterium Streptococcus salivarius, a non-biofilm forming, and otherwise harmless inhabitant of the human mouth, actually inhibits the formation of dental biofilms, otherwise known as plaque. Two enzymes this bacteria produces are responsible for this inhibition.

Investigators from Japan show in vitro that the bacterium Streptococcus salivarius, a non-biofilm forming, and otherwise harmless inhabitant of the human mouth, actually inhibits the formation of dental biofilms, otherwise known as plaque. Two enzymes this bacteria produces are responsible for this inhibition.

Related Articles


The research is published in the March 2011 issue of the journal Applied and Environmental Microbiology.

"FruA may be useful for prevention of dental caries," corresponding author Hidenobu Senpuku, of the National Institute of Infectious Diseases, Tokyo says of one of the enzymes. "The activity of the inhibitors was elevated in the presence of sucrose, and the inhibitory effects were dependent on the sucrose concentration in the biofilm formation assay medium," the researchers write.

"We show that FruA produced by S. salivarius inhibited S. mutans biofilm formation completely in the in vitro assay supplemented with sucrose," the researchers write. S. salivarius is the primary species of bacteria inhabiting the mouth, according to the report.

The authors suggest that FruA may actually regulate microbial pathogenicity in the oral cavity. They found that a commercial FruA, produced by Aspergillus niger, was as effective as S. salivarius FruA at inhibiting S. mutans biofilm formation, despite the fact that its amino acid composition is somewhat different from that of S. salivarius.

FruA is produced not only by S. salivarius, but by other oral streptococci. Much of the oral microbial flora consists of many beneficial species of bacteria that help maintain oral health and control the progression of oral disease.

(A. Ogawa, S. Furukawa, S. Fujita, J. Mitobe, T. Kawarai, N. Narisawa, T. Sekizuka, M. Kuroda, K. Ochiai, H. Ogihara, S. Kosono, S. Yoneda, H. Watanabe, Y. Morinaga, H. Uematsu, and H. Senpuku, 2011. Inhibition of Streptococcus mutans biofilm formation by Streptococcus salivarius FruA. Appl. Environ. Microbiol. 77:1572-1580.)


Story Source:

The above story is based on materials provided by American Society for Microbiology. Note: Materials may be edited for content and length.


Journal Reference:

  1. A. Ogawa, S. Furukawa, S. Fujita, J. Mitobe, T. Kawarai, N. Narisawa, T. Sekizuka, M. Kuroda, K. Ochiai, H. Ogihara, S. Kosono, S. Yoneda, H. Watanabe, Y. Morinaga, H. Uematsu, H. Senpuku. Inhibition of Streptococcus mutans Biofilm Formation by Streptococcus salivarius FruA. Applied and Environmental Microbiology, 2011; 77 (5): 1572 DOI: 10.1128/AEM.02066-10

Cite This Page:

American Society for Microbiology. "Streptococcus enzyme could compete with toothbrushes, dental floss." ScienceDaily. ScienceDaily, 22 March 2011. <www.sciencedaily.com/releases/2011/03/110321203139.htm>.
American Society for Microbiology. (2011, March 22). Streptococcus enzyme could compete with toothbrushes, dental floss. ScienceDaily. Retrieved March 5, 2015 from www.sciencedaily.com/releases/2011/03/110321203139.htm
American Society for Microbiology. "Streptococcus enzyme could compete with toothbrushes, dental floss." ScienceDaily. www.sciencedaily.com/releases/2011/03/110321203139.htm (accessed March 5, 2015).

Share This


More From ScienceDaily



More Health & Medicine News

Thursday, March 5, 2015

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Bupa Eyes India Healthcare Opportunities

Bupa Eyes India Healthcare Opportunities

Reuters - Business Video Online (Mar. 5, 2015) — Bupa is hoping to expand in India&apos;s fast-growing health insurance market, once a rule change on foreign investment is implemented. The British private healthcare group&apos;s CEO tells Grace Pascoe why it&apos;s so keen on the new opportunity. Video provided by Reuters
Powered by NewsLook.com
Doctor in Your Pocket Is Getting Smarter

Doctor in Your Pocket Is Getting Smarter

Reuters - Business Video Online (Mar. 5, 2015) — Mobile apps are turning smartphones into a personal doctors, with users able to measure heart rate, blood pressure and even blood sugar. But will it change our behaviour? Ivor Bennett reports from the Mobile World Congress in Barcelona. Video provided by Reuters
Powered by NewsLook.com
AbbVie Inks $21B Deal To Buy Cancer Drugmaker Pharmacyclics

AbbVie Inks $21B Deal To Buy Cancer Drugmaker Pharmacyclics

Newsy (Mar. 5, 2015) — AbbVie announced Wednesday it will buy cancer drugmaker Pharmacyclics in a $21 billion deal. Video provided by Newsy
Powered by NewsLook.com
Adults Only Get The Flu Twice A Decade, Researchers Say

Adults Only Get The Flu Twice A Decade, Researchers Say

Newsy (Mar. 4, 2015) — Researchers found adults only get the flu about once every five years. Scientists analyzed how a person&apos;s immunity builds up over time as well. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:

Strange & Offbeat Stories

 

Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins