Featured Research

from universities, journals, and other organizations

Smoking does not influence breast cancer risk among obese women, study suggests

Date:
April 3, 2011
Source:
American Association for Cancer Research
Summary:
Smoking increases the risk of breast cancer, but the risk differs by obesity status in postmenopausal women, according to new data.

Smoking increases the risk of breast cancer, but the risk differs by obesity status in postmenopausal women, according to data from an analysis of the Women's Health Initiative observational study.

A significant association between smoking and breast cancer risk was observed in non-obese women, but not in obese women. The results were similar regardless of whether obesity was defined by body mass index (BMI) or waist circumference.

Juhua Luo, Ph.D., assistant professor in the department of community medicine at West Virginia University, and colleagues examined the relationship between obesity, smoking and breast cancer risk. Luo presented these study results at the AACR 102nd Annual Meeting 2011, held in Orlando, Florida, April 2-6.

"We found an association between smoking and breast cancer risk among non-obese women, which is understandable because tobacco is a known carcinogen," Dr. Luo said. "However, we did not find the same association between smoking and breast cancer risk among obese women. This result was surprising."

The study included 76,628 women aged 50 to 79 years old who had no previous history of cancer. Participants were part of the Women's Health Initiative observational study. They were recruited between 1993 and 1998 at 40 U.S. centers and were followed until 2009.

Obesity was measured by BMI and by waist circumference, and the results were adjusted for other breast cancer risk factors.

The study results indicated that non-obese women with a BMI less than 30 who had a history of smoking had a significantly higher risk for breast cancer. Those who smoked from 10 to 29 years had a 16 percent excess risk; those with a 30- to 49-year history of smoking had a 25 percent excess risk; and those with 50 or more years of smoking had a 62 percent excess risk. However, this same association was not found among women with a BMI over 30.

The researchers then examined the data according to waist circumference to determine if the type of fat distribution -- general compared with abdominal obesity -- affected the results. When obesity status was defined by a waist circumference greater than 88 cm, similar results were found.

Despite the study's finding that smoking did not affect breast cancer risk among obese postmenopausal women, Luo emphasized that she does not want to give the public the wrong message. Previous research has established that obesity alone is a risk factor for postmenopausal breast cancer.

"Smoking and obesity are among the leading causes of morbidity and mortality, both of which have substantial consequences on health," she said. "This is only the first study to examine the interaction between smoking, obesity and breast cancer risk. The main conclusion from this research is that more studies are needed to confirm these results."


Story Source:

The above story is based on materials provided by American Association for Cancer Research. Note: Materials may be edited for content and length.


Cite This Page:

American Association for Cancer Research. "Smoking does not influence breast cancer risk among obese women, study suggests." ScienceDaily. ScienceDaily, 3 April 2011. <www.sciencedaily.com/releases/2011/04/110403205225.htm>.
American Association for Cancer Research. (2011, April 3). Smoking does not influence breast cancer risk among obese women, study suggests. ScienceDaily. Retrieved April 20, 2014 from www.sciencedaily.com/releases/2011/04/110403205225.htm
American Association for Cancer Research. "Smoking does not influence breast cancer risk among obese women, study suggests." ScienceDaily. www.sciencedaily.com/releases/2011/04/110403205225.htm (accessed April 20, 2014).

Share This



More Health & Medicine News

Sunday, April 20, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Nine-Month-Old Baby Can't Open His Mouth

Nine-Month-Old Baby Can't Open His Mouth

Newsy (Apr. 19, 2014) Nine-month-old Wyatt Scott was born with a rare disorder called congenital trismus, which prevents him from opening his mouth. Video provided by Newsy
Powered by NewsLook.com
'Holy Grail' Of Weight Loss? New Find Could Be It

'Holy Grail' Of Weight Loss? New Find Could Be It

Newsy (Apr. 18, 2014) In a potential breakthrough for future obesity treatments, scientists have used MRI scans to pinpoint brown fat in a living adult for the first time. Video provided by Newsy
Powered by NewsLook.com
Little Progress Made In Fighting Food Poisoning, CDC Says

Little Progress Made In Fighting Food Poisoning, CDC Says

Newsy (Apr. 18, 2014) A new report shows rates of two foodborne infections increased in the U.S. in recent years, while salmonella actually dropped 9 percent. Video provided by Newsy
Powered by NewsLook.com
Scientists Create Stem Cells From Adult Skin Cells

Scientists Create Stem Cells From Adult Skin Cells

Newsy (Apr. 17, 2014) The breakthrough could mean a cure for some serious diseases and even the possibility of human cloning, but it's all still a way off. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins