Featured Research

from universities, journals, and other organizations

Anatomic differences found after robotic-assisted radical prostatectomy

Date:
April 11, 2011
Source:
Boston University Medical Center
Summary:
Researchers have concluded that the anatomy of the pelvis following robotic-assisted radical prostatectomy (RARP) is considerably different when compared to the anatomy of the pelvis following an open prostatectomy (OP). These findings, which are the first to ever compare pelvic anatomy following RARP and OP surgery, may have implications for patients requiring post-operative radiation.

Researchers from Boston University School of Medicine (BUSM) have concluded that the anatomy of the pelvis following robotic-assisted radical prostatectomy (RARP) is considerably different when compared to the anatomy of the pelvis following an open prostatectomy (OP). These findings, which are the first to ever compare pelvic anatomy following RARP and OP surgery, may have implications for patients requiring post-operative radiation.

Related Articles


The study currently appears online in Practical Radiation Oncology.

Prostate cancer is the most common non-cutaneous cancer diagnosed in men globally. In 2009, there were 192,280 new cases diagnosed, and 27,360 deaths from prostate cancer in the U.S. The surgical approaches to prostatectomy include open (OP), laparoscopic, and robot-assisted prostatectomy. In particular, robot-assisted prostatectomy has rapidly gained acceptance in the urologic community and is now in widespread and rapidly expanding use. Currently it is estimated that nearly 60 percent of all prostatectomies in the United States are performed using the robotic technique.

The role of postoperative radiation therapy has been well established. A 1992 randomized, multicenter phase III study by the European Organization for Research and Treatment of Cancer indicated biochemical progression-free survival was statistically significantly improved in the patients treated with adjuvant radiation therapy (74 percent) versus patients treated by radical prostatectomy alone (52.6 percent).

The researchers compared post-operative pelvic MRI scans on consecutive prostatectomy patients (15 RARP and 10 OP) measuring 13 distinct anatomic distances to determine differences in each of the parameters between RARP and OP.

According to the researchers the pelvic anatomy post-RARP is considerably different from the pelvic anatomy post-OP. "The most clinically relevant differences observed in the current study were the superior mediolateral separation of the levator ani and the trend toward statistical significance in the separation of the bladder from the rectum, representing the anterior, posterior, and lateral borders of treatment volumes," explained lead author Ariel Hirsch, MD, an assistant professor of radiation oncology at BUSM "Thus, careful attention must be paid in planning the posterior and lateral margins to ensure that coverage is sufficient in men who have undergone RARP. To that end, our data support that the CTV borders as suggested by the Radiation Therapy Oncology Group guidelines be expanded five mm beyond the anterior rectal wall posteriorly and five mm beyond the levator ani muscles laterally in men who have undergone RARP," she added.

The researchers believe that as RARP continues to become a more widespread surgical option for the management of localized prostate cancer, the radiation field design may need to be further adjusted.


Story Source:

The above story is based on materials provided by Boston University Medical Center. Note: Materials may be edited for content and length.


Journal Reference:

  1. Ariel E. Hirsch, John J. Cuaron, Milos J. Janicek, Kit Mui, Richard J. Lee, David S. Wang, Richard K. Babayan, Ann C. Zumwalt, Gretchen A. Gignac, Wen Tao, Alexander Ozonoff, Anthony L. Zietman et al. Anatomic differences after robotic-assisted radical prostatectomy and open prostatectomy: implications for radiation field design. Practical Radiation Oncology, Volume 1, Issue 2 , Pages 115-125, April 2011 DOI: 10.1016/j.prro.2010.11.007

Cite This Page:

Boston University Medical Center. "Anatomic differences found after robotic-assisted radical prostatectomy." ScienceDaily. ScienceDaily, 11 April 2011. <www.sciencedaily.com/releases/2011/04/110411103753.htm>.
Boston University Medical Center. (2011, April 11). Anatomic differences found after robotic-assisted radical prostatectomy. ScienceDaily. Retrieved November 28, 2014 from www.sciencedaily.com/releases/2011/04/110411103753.htm
Boston University Medical Center. "Anatomic differences found after robotic-assisted radical prostatectomy." ScienceDaily. www.sciencedaily.com/releases/2011/04/110411103753.htm (accessed November 28, 2014).

Share This


More From ScienceDaily



More Health & Medicine News

Friday, November 28, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Ebola Leaves Orphans Alone in Sierra Leone

Ebola Leaves Orphans Alone in Sierra Leone

AFP (Nov. 27, 2014) — The Ebola epidemic sweeping Sierra Leone is having a profound effect on the country's children, many of whom have been left without any family members to support them. Duration: 01:02 Video provided by AFP
Powered by NewsLook.com
Experimental Ebola Vaccine Shows Promise In Human Trial

Experimental Ebola Vaccine Shows Promise In Human Trial

Newsy (Nov. 27, 2014) — A recent test of a prototype Ebola vaccine generated an immune response to the disease in subjects. Video provided by Newsy
Powered by NewsLook.com
Pet Dogs to Be Used in Anti-Ageing Trial

Pet Dogs to Be Used in Anti-Ageing Trial

Reuters - Innovations Video Online (Nov. 26, 2014) — Researchers in the United States are preparing to discover whether a drug commonly used in human organ transplants can extend the lifespan and health quality of pet dogs. Video provided by Reuters
Powered by NewsLook.com
Today's Prostheses Are More Capable Than Ever

Today's Prostheses Are More Capable Than Ever

Newsy (Nov. 26, 2014) — Advances in prosthetics are making replacement body parts stronger and more lifelike than they’ve ever been. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:

Strange & Offbeat Stories

 

Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins